pseudopodia
gene
reagent
sample publication
sample review
WASF2
WASP family member 2
total:2
Increased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 correlated with poor prognosis of hepatocellular carcinoma. 2006 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human WAVE2 antibody (c-14) was used in protein and paraffin sections from human tumor, and which were used in western blot and immunohistochemistry, to study the relationship between Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 and poor prognosis of hepatocellular carcinoma. more
fascin
fascin actin-bundling protein 1
total:6
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys. 2008 to the paper
Neomarkers anti-Fascin antibody was used to perform immunohistochemistry in order to study the determinants of the level of viremia in naturally SIV-infected SMs. more
cortactin
total:17
Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp. 2010 to the paper
Upstate anti-cortactin antibody was used for performing immunohistochemistry in order to study the role and contribution of CIP4 in human cancer cell motility and invasion. more
Rac1
Rac family small GTPase 1
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
VASP
vasodilator stimulated phosphoprotein
total:10
Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function. 2009 to the paper
Chemicon International rabbit polyclonal anti-VASP antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the roles of ADMA and DDAH in the regulation of pulmonary endothelial barrier function. more
CFL1
cofilin 1
total:8
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Sigma-Aldrich polyclonal anti-cofilin and anti-phospho-cofilin antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
cdc42
cell division cycle 42
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
ACTN4
actinin alpha 4
total:3
The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3. 2008 to the paper
Sigma mouse monoclonal anti-alpha-actinin clone BM-75.2 was used to perform western blot and immunoprecipitation in order to study the interaction function between parafibromin and muscle alpha-actinins. more
RhoA
ras homolog family member A
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
paxillin
total:51
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. 2008 to the paper
Upstate mouse monoclonal anti-paxillin was used to perform immunocytochemistry in order to show that Rho/ROCK/MLC pathway could be inhibited by DCL1 in hepatocellular carcinoma. more
WAS
WASP actin nucleation promoting factor
total:1
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-WASP antibody was used in western blot to study the role for EspF in pedestal maturation and the disruption of paracellular permeability.
ITGB4
integrin subunit beta 4
total:12
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-ITGB4 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
actin
actin alpha 1, skeletal muscle
total:77
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Invitrogen anti-Phalloidin antibody was used to perform immunohistochemistry in order to study synaptic plasticity. more
beta1 integrin
integrin subunit beta 1
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
PAK1
p21 (RAC1) activated kinase 1
total:29
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics rabbit monoclonal anti-Pak1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
MT1-MMP
matrix metallopeptidase 14
total:15
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Acris anti-MMP14(113-5B7) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
FAK
protein tyrosine kinase 2
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
ERK2
mitogen-activated protein kinase 1
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
ERK1
mitogen-activated protein kinase 3
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
VEGF
vascular endothelial growth factor A
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
EGFR
epidermal growth factor receptor
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more