prostatic neoplasms
gene
reagent
sample publication
sample review
total:52
Overcoming mutation-based resistance to antiandrogens with rational drug design. 2013 to the paper
Upstate anti-AR (PG-21) antibody was used to perform ChIP in order to study the rational drug design for castration-resistant prostate cancer without mutation-based resistance to antiandrogens. more
total:18
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. 2008 to the paper
DAKO polyclonal anti-PSA antibody was used in immunohistochemistry in order to investigate mechanisms by which advanced prostate cancers maintain AR-mediated gene expression following castration more
total:1
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. 2007 to the paper
Abgent anti-PRPS1/2/3 antibody was used to perform western blot in order to study the dependency on oxidative phosphorylation during transformation of human mesenchymal stem cells.
total:1
Epigenetic silencing of novel tumor suppressors in malignant melanoma. 2006 to the paper
Santa Cruz Biotechnology HOXB13 (F-9) antibody was used in western blot to study epigenetic silencing of novel tumor suppressors in malignant melanoma
total:1
Mechanisms directing the nuclear localization of the CtBP family proteins. 2006 to the paper
BD Transduction Laboratories mouse monoclonal anti-mCtBP2 antibody was used in human HeLa cells and in western blot, immunocytochemistry to study the nuclear import of the various CtBP proteins and splice isoforms is differentially regulated.
total:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 to the paper
Santa Cruz Biotechnology anti-HNF1B antibody was used for western blot in order to investigate the role of HNF-1beta in the regulation of PKD Modifier Gene Kif12. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:1
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Abnova anti-ETV1 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway.
total:6
KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA. 2009 to the paper
Santa Cruz anti-Pim-1 antibody was used to perform western blot and immunoprecipitation in order to study Pim-1 and Pim-3 kinases were required to KSHV reactivation. more
total:2
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
Dako prostatic acid phosphatase antibody was used in immunohistochemistry at 1:50 dilution in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:4
Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium. 2009 to the paper
Santa Cruz FOXA1 antibody was used in western blot and immunohistochemistry to incubate membranes in order to investigate the role of TEAD1 and its cofactors YAP65 and FOXA2 in the regulation of the dysgenesis of the pigment epithelium. more
total:1
Endogenous coactivator ARA70 interacts with estrogen receptor alpha (ERalpha) and modulates the functional ERalpha/androgen receptor interplay in MCF-7 cells. 2005 to the paper
Santa Cruz Biotechnology ARA70 antibody was used in western blot, immunoprecipitation, immunocytochemistry, and ChIP assay to study the interaction of ARA70 with estrogen receptor alpha (ER alpha) in MCF-7 cells
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:3
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Dako anti-AMACR(13H4) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
total:17
IGFBP3 colocalizes with and regulates hypocretin (orexin). 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-human IGFBP3 antibody was used in western blot to study the association of IGFBP3 with hypocretin. more
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
ProteinTech anti-ELAC2 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
total:1
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
IGBMC monoclonal anti-ELK4 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability.
total:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 to the paper
Upstate Biotechnology anti Vav3 antibody was used in western blot and immunohistochemistry to study the activation of estrogen receptor by Vav3 oncogene and Vav3 overexpression in human breast cancer more
total:1
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. 2006 to the paper
Cayman Chemical rabbit polyclonal anti-hepsin antibody was used in immunohistochemistry to detect hepsin in normal human prostate, benign prostatic hyperplasia (BPH), grades 2 to 5 prostate cancer tissues, and bone metastases
total:13
Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. 2009 to the paper
Santa Cruz anti-Ets-1 antibody was used in western blot in order to identify factors for reactivating latent HIV-1 without inducing global T cell activation more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:28
Monocyte 15-lipoxygenase gene expression requires ERK1/2 MAPK activity. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-human Egr-1 antibody was used to perform immunoblotting in order to study the important role of ERK1/2 in mediating IL-13-induced monocyte 15-LO expression. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:3
Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. 2005 to the paper
Santa Cruz Biotechnology anti-human PEA3 mouse monoclonal antibody was used in immunohistochemistry to study the association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis more
total:8
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p107 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:9
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
Assay Designs anti-manganese superoxide dismutase antibody was used to perform western blot in order to study the interaction between F1L and endogenous Bak. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:2
Increased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancer. 2009 to the paper
Abcam rabbit anti-delta-catenin antibody (1:100) was used to perform western blot and immunohistochemistry in order to show the mechanism of increased expression of delta-catenin in prostate cancer. more
total:3
Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. 2008 to the paper
Santa Cruz Biotechnology Inc Klf6 rabbit polyclonal antibodies were used to probe nitrocellulose blots in order to study differential regulation of Kr ppel-like factor family transcription factor expression in neonatal rat cardiac myocytes. more
total:24
Estrogen receptor beta-mediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma. 2009 to the paper
GeneTex mouse monoclonal anti-ER antibody (C14C8) was used in immunohistochemistry, immunocytochemistry, and immunoprecipitation to study the effect of estrogen receptormediated nuclear interaction between IRS-1 and Rad51 on homologous recombination directed DNA repair in medulloblastoma. more
total:4
The focal adhesion protein Hic-5 is highly expressed in the rat myometrium during late pregnancy and labour and co-localizes with FAK. 2007 to the paper
BD Biosciences mouse monoclonal Hic-5 specific antibody was used in western blot (1:2000) and immunohistochemistry (1:50) to characterize Hic-5 mRNA and protein expression in the rat myometrium during pregnancy and labour. more
total:5
Activation of p53 by MEG3 non-coding RNA. 2007 to the paper
Upstate Biotechnology anti-NAG-1 antibody was used in western blot to study the role of MEG3 in tumor suppression. more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP24A1 (1:150) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more