pathologic neovascularization
gene
reagent
sample publication
sample review
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 to the paper
Santa Cruz anti-Flk-1 antibody was used to perform immunoprecipitation in order to reveal the critical role of prorenin receptor and vacuolar H+-ATPase-mediated acidification in Wnt signaling. more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:1
Alternative splicing of vasohibin-1 generates an inhibitor of endothelial cell proliferation, migration, and capillary tube formation. 2008 to the paper
R&D systems vasohibin antibody was used in western blot to compare the alternative splicing product of vasohibin 1 to major isoform (VASH1A) for antiangiogenic effects on endothelial colony forming cells.
total:16
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 to the paper
R&D Systems goat anti-human VEGFR-1 polyclonal antibody (catalog number: AF321) was used to perform immunochemistry assays in order to demonstrate that VEGFR-1 expression is not related to the risk of cancer progression following radical prostatectomy. more
total:20
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 to the paper
Acbam mouse monoclonal antibody against human and mouse thrombospondin-1 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth. more
total:4
Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration. 2008 to the paper
R&D Systems anti-endostatin antibody was used to perform immunohistochemistry in order to study the level of angiogenesis inhibitors in eyes with age-related macular degeneration. more
total:3
A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit. 2008 to the paper
Upstate mouse monoclonal anti-FGF/anti-FGF-2 antibody (clone bFM-2) was used in immunohistochemistry to determine the effects of the vascular endothelial growth factor (VEGF) A165 delivered using a high capacity adenoviral vector (HC Ad.VEGF-A) on vascular growth and pathological changes in the rabbit eye. more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:13
Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies. 2008 to the paper
R&D Systems anti-105 antibody was used to perform flow cytometry in order to study the new characterization about the dissection of normal bone marrow progenitor cells more
total:6
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 to the paper
R&D Systems anti-PTN antibody was used in immunocytochemistry in order to demonstrate that vasculogenesis in human MM may develop from tumoral production of pleiotrophin, which induces the transdifferentiation of monocytes into VECs. more
total:1
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. 2007 to the paper
I. B. Lobov (Regeneron Pharmaceuticals) Dll4 antibody was used in immunohistochemistry to study the role of Dll4 during vascular growth and differentiation.
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
total:9
The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. 2008 to the paper
R&D Systems CXCR2 IgG2a antbody was used to inhibit cell adhesion in order to study the role of the chemokines MCP-1, GRO-alpha, IL-8, and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques more
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:3
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP3 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:10
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics anti-VEGF antibody (1:1000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
total:7
Constitutive overexpression of pigment epithelium-derived factor inhibition of ocular melanoma growth and metastasis. 2010 to the paper
Santa Cruz anti-PEDF antibody was used in western blot to investigate the role of lentivirus-mediated gene transfer of PEDF in the regulation of the growth of ocular melanoma and its hepatic micrometastasis. more
total:19
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 to the paper
eBioscience anti-CD144 antibody was used in immunohistochemistry in order to demonstrate that vasculogenesis in human MM may develop from tumoral production of pleiotrophin, which induces the transdifferentiation of monocytes into VECs. more
total:9
Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha. 2010 to the paper
Novus Biologicals HIF2alpha antibody was used for ChIP assays in order to study HIF-binding and Ets-binding motifs on the PTPRZ1 promoter and show that PTPRZ1 can be activated by HIF-2. more
total:5
Expression of angiopoietin-2 is correlated with vascularization and tumor size in human colorectal adenocarcinoma. 2007 to the paper
Santa Cruz Biotechnology rabbit-derived polyclonal Ang-1 antibody was used in immunohistochemistry to study angiopoietin-2 expression in human colorectal adenocarcinoma more
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
total:9
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
R&D Systems monoclonal anti-human HGF antibody (MoAb) was used in blocking or activating expriments to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
total:125
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Millipore anti-mouse CD31 antibody was used to perform immunohistochemistry in order to study the inhibition of antifungal drug thiabendazole to tumor growth in a mouse xenograft model. more
total:13
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Santa Cruz Biotechnology anti-EphA2 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:8
Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. 2008 to the paper
Oncogene Research Products rabbit polyclonal anti-human maspin antibody was used in immunocytochemistry to determine whether DNA methylation of the maspin promoter and histone H3 dimethylation are involved in the mechanism of down regulation of maspin synthesis in human corneal stromal fibroblasts and myofibroblasts. more
total:60
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Cell Signaling anti-S6K1 and phospho-T389 S6K1 was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation. more
total:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 to the paper
Santa Cruz Biotechnology NRP-1 antibody was used in western blot and immunohistochemistry to study the role of placenta growth factor in malignancy. more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 to the paper
BD Biosciences tissue factor antibody (CD142, clone number HTF-1) was used in western blot to detect its expression in culture medium and cell lysate from versican G3- or vector-transfected astrocytoma cell line U87 more
total:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoC antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:4
The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells. 2009 to the paper
Santa Cruz anti-RON antibody was used to perform western blot in order to study the oncogenic behavior of the RON receptor tyrosine kinase in breast epithelial cells. more
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:3
Correlation of vascular endothelial growth factor-D expression and VEGFR-3-positive vessel density with lymph node metastasis in gastric carcinoma. 2008 to the paper
R&D Systems goat polyclonal anti-VEGF-D antibody was used in immunohistochemistry to study the clinical value of VEGF-D expression and VEGFR-3 positive vessel density in gastric carcinoma with regard to lymphangiogenesis in paraffin sections from human tumor. more
total:8
Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains. 2008 to the paper
Santa Cruz Biotechnology anti-AQP1 antibody (H-55) was used in immunocytochemistry and western blot to detect AQP1 expression in human astrocytes, and in immunohistochemistry to investigate AQP1 expression in cerebral cortex from AD patients. more
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
total:1
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-AP antibody was used to perform immunofluorescence in order to study the involvement of apelin in fibrogenesis during human liver disease.
total:4
Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells. 2005 to the paper
Santa Cruz Biotechnology anti-CCN1 antibody was used in western blot and immunohistochemistry to study the role of CCN in ovarian carcinomas. more
total:8
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
Santa Cruz polyclonal anti-Id1 was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more