pancreatic neoplasms
gene
reagent
sample publication
sample review
total:5
The clinicopathological and prognostic significance of MUC-1 expression in Japanese gastric carcinomas: an immunohistochemical study of tissue microarrays. 2008 to the paper
NovoCastra anti-human MUC-4 antibody was used to perform immunohistochemistry in order to study the clinicopathological significance of MUC-1 expression in gastric carcinomas. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Bethyl Laboratories anti-menin antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis. more
total:3
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity. 2009 to the paper
Abgent rabbit anti-DCK was used to perform western blot in order to show that resistance to cytarabine arabinoside is associated with population-specific genetic variants. more
total:8
Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activity. 2013 to the paper
R&D systems monoclonal anti-mouse SHH N-term peptide antibody and biotinylated anti-mouse SHH antibody were used to perform ELISA in order to investigate the role of CDON in regulating tumor cell survival. more
total:1
Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance. 2009 to the paper
Abgent anti-ENT1 polyclonal antibody was used to perform western blot in order to understand the ribavirin uptake and cell-based mechanisms of ribavirin resistance.
total:4
Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression. 2009 to the paper
Santa Cruz Biotechnology anti-Pim-3 antibody was used to perform western blot in order to study the levels of Pim-3 expression under hypoxia compared with normoxia in different solid tumors, such as 293, Hela, and PCI-43. more
total:8
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Santa Cruz Pdx1 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
total:3
Immunocytochemical study of the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma. 2007 to the paper
Novocastra Laboratory Vision BioSystems mesothelin antibody was used in immunohistochemistry to study the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma. more
total:2
Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. 2006 to the paper
Santa Cruz Biotechnology Gli-1 antibody was used in immunocytochemistry to determine whether the synthetic microRNAs (miRNA) could effectively target tumor cells. more
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:2
An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients. 2007 to the paper
Chemicon International mouse monoclonal anti-RRM1 (1:500) antibody was used in western blot to study the association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients more
total:3
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
Santa Cruz Biotechnology anti-ATRX was used to perform western-blot and immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3. more
total:4
TDP-43-mediated neuron loss in vivo requires RNA-binding activity. 2010 to the paper
Invitrogen anti-V5 antibody(1:500)was used to perform immunohistochemistry in order to study the function of ribonucleoprotein TDP-43. more
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:14
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
Santa Cruz Biotechnology anti-DAXX was used to perform western-blot and immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3. more
total:2
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). 2007 to the paper
Abcam GLP-1R antibody was used in western blot to study protein expression of GLP-1R to reveal tissue-specific strain differences in pancreas (congenic>B6) and stomach (B6>congenic). more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:10
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma. 2009 to the paper
Chemicon anti-CD24 antibody was used to perform immunohistochemistry in order to find out the potential therapeutic targets of the human head and neck squamous cell carcinoma. more
total:10
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Neomarkers anti-MUC5AC antibody was used to perform western blot and immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
total:2
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter by nuclear receptors liver receptor homologue-1 and small heterodimer partner: a mechanism for differential regulation of cholesterol synthesis and uptake. 2006 to the paper
Santa Cruz Biotechnology anti-LRH-1 antibody (catalog number SC-25389x) was used in human 293T cells and in ChIP assay to study the effect of nuclear receptors liver receptor homologue-1 and small heterodimer partner on 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:1
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Biomol NTS rabbit antibody was used in immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression.
total:23
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
Zymed Laboratories chromogranin A antibody was used in immunohistochemistry in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:6
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Santa Cruz anti-NeuroD1 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:5
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Cell signaling rabbit anti-NFAT1 antibody was used to perform immunocytochemistry in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:10
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
EMD anti-BRCA2 antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more
total:4
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. 2005 to the paper
Santa Cruz anti-GDNF antibody was used in immunohistochemistry to compare GDNF, BDNF, or both, for their capabilities to correct behavioral deficits and protect nigrostriatal dopaminergic neurons in a rat model of PD.. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:4
The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells. 2009 to the paper
Santa Cruz anti-RON antibody was used to perform western blot in order to study the oncogenic behavior of the RON receptor tyrosine kinase in breast epithelial cells. more
total:1
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6. 2007 to the paper
Biogen Idec monoclonal antibody 6.2E5 was used for western blotting, immunofluorescence, and immunohistochemistry (1 ug/ml) and 6.3G9 (a function-blocking antibody) was used for the migration and soft-agar assays (30 ug/ml) and for flow cytometry to study the induction of tumorigenesis and enhancement of cell motility of prostate epithelial cells by constitutively activated Stat3 through integrin beta 6.
total:4
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling. 2007 to the paper
Lab Vision S100A4 antibody was used in western blot to report an increase in S100A6 protein level in colon and lung cancer cells postexposure to ionizing radiation. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:3
HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells. 2009 to the paper
Santa Cruz anti-HMGA1 antibody was used to perform western blot in order to study the role of HMGA2 in maintaining the oncogenic RAS-induced epithelial-mesenchymal transition. more
total:2
Differential expression of runx2 and Indian hedgehog in cartilaginous tumors. 2007 to the paper
Santa Cruz goat polyclonal antibody C-15 against Ihh was used in immunohistochemistry to study the differential expression of runx2 and Indian hedgehog in cartilaginous tumors more
total:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-HDAC1 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:6
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Zymed mouse anti-transferrin receptor antibody was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
total:2
Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. 2009 to the paper
Abnova anti-NDRG1 (H00010397M03) antibody was used to perform western blot, flow cytometry, and immunohistochemistry/immunocytochemistry in order to study the altered expression levels of metastasis-related plasma membrane proteins of human breast cancer cells. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:2
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Novus Biologicals anti-Abcc4 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate. more
total:6
Identification and characterization of ovarian cancer-initiating cells from primary human tumors. 2008 to the paper
Santa Cruz Biotechnology monoclonal anti-cancer antigen-125 (CA-125) antibody was used in immunocytochemistry to identify and characterize a self-renewing subpopulation of human ovarian tumor cells. more
total:11
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
BD Biosciences anti-EpCam antibody was used to perform purification of primary lung tumor cells in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:16
Genes associated with the tumour microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphoma. 2008 to the paper
Novocastra anti-Galectin-3 antibody was used to perform immunohistochemistry in order to study the diversity of gene expression profiles in tumours. more
total:1
Premature terminal differentiation and a reduction in specific proteases associated with loss of ABCA12 in Harlequin ichthyosis. 2009 to the paper
Santa Cruz anti-KLK7 antibody was used to perform immunohistochemistry in order to study the morphological and biochemical alterations associated with the loss of ABCA12 in harlequin ichthyosis.
total:15
Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton. 2005 to the paper
Santa Cruz Biotechnology protein kinase C mu (C-20) antibody was used in western blot to study amino acid-stimulated Ca2+ oscillations through a phospholipase c/inositol 1, 4, 5-trisphosphate-independent pathway. more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:40
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Santa Cruz Biotechnology PE-conjugated anti-IGF-1R antibody was used in flow cytometry to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 to the paper
Zymed anti-somatostatin antibody was used to perform western blot and immunohistochemistry in order to study the acinar polarity defects and cystic neoplasms induced by Lkb1-deficient in pancreas.