ovarian neoplasms
gene
reagent
sample publication
sample review
total:42
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Calbiochem anti-BRCA1 monoclonal antibody was used to perform immunoprecipitation in order to study the function of apicobasal polarity and regulation of stem cell in breast cancer more
total:10
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
EMD anti-BRCA2 antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more
total:6
Identification and characterization of ovarian cancer-initiating cells from primary human tumors. 2008 to the paper
Santa Cruz Biotechnology monoclonal anti-cancer antigen-125 (CA-125) antibody was used in immunocytochemistry to identify and characterize a self-renewing subpopulation of human ovarian tumor cells. more
total:3
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
ABCAM anti-FOXL2 antibody was used in immunocytochemistry in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more
total:3
Role of RAD51C and XRCC3 in genetic recombination and DNA repair. 2007 to the paper
Dr. Stephen C. West (London Research Institute) monoclonal (2H11) and polyclonal (SWE31 and SWE68) RAD51C antibodies (raised against purified denatured full-length RAD51C protein) and polyclonal RAD51C antibody (SWE72) (raised against a synthetic peptide corresponding to residues 41-80 of RAD51C) were used in western blot (2H110), immunohistochemistry (2H110, SWE72, SWE31, and SWE68), and ChIP assay (SWE72 and SWE68) on mouse testicular cells to study the role of RAD51C and XRCC3 in genetic recombination and DNA repair more
total:1
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Santa Cruz Biotechnology anti-ARID1a antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation.
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:3
Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination. 2006 to the paper
Novus Biologicals anti-RAD51D antibody was used in western blot and immunoprecipitation to study Athe role of RAD51D ATPase motifs during homologous recombinatio more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:1
Alteration in the activation state of new inflammation-associated targets by phospholipase A2-activating protein (PLAA). 2008 to the paper
Santa Cruz Biotechnology anti-annexin A4 antibody was used for western blot in order to investigate the role of PLAA in the regulation of the activity of inflammation associate targets.
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:1
Premature terminal differentiation and a reduction in specific proteases associated with loss of ABCA12 in Harlequin ichthyosis. 2009 to the paper
Santa Cruz anti-KLK5 antibody was used to perform immunohistochemistry in order to study the morphological and biochemical alterations associated with the loss of ABCA12 in harlequin ichthyosis.
total:55
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-cyclin E antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:4
The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. 2008 to the paper
Santa Cruz vitronectin antibody was used in western blot in order to study the effect of RGD peptides on osseointegration of hydroxyapatite biomaterials more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:7
Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection. 2010 to the paper
Labvision rabbit anti-Claudin-3 (clone WN1 222-5) polyclonal antibody was used to perform immunohistochemistry in order to shown that in the absence of SIV infection, PTM have damage to their gastrointestinal tract and increased basal levels of microbial translocation and immune activation. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:37
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Chemicon anti-B-Tubulin antibody was used to perform immunohistochemistry in order to study synaptic plasticity. more
total:6
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
Abcam anti-Nanog antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:3
Immunocytochemical study of the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma. 2007 to the paper
Novocastra Laboratory Vision BioSystems mesothelin antibody was used in immunohistochemistry to study the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma. more
total:18
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.. 2013 to the paper
Cell Signaling rabbit anti-mFOXO3(phospho-S252)/hFOXO3(phospho-S253) antibody was used to perform western blot in order to investigate the regulatory effect of calcineurin and CAMKII on the lifespan of Caenorhabditis elegans. more
total:5
Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. 2013 to the paper
Santa Cruz anti-SnoN antibody was used to perform western blot to study the role of BMP-Smad signaling during motor axon extension. more
total:24
Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men. 2008 to the paper
Calbiochem anti-MLH1 antibody (1:75) was used to perform western blot and immunoprecipitation in order to study the function of small ubiquitin-related modifier (SUMO) 1, SUMO-2/3 and SUMOylation. more
total:2
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Bethyl Laboratories anti-FANCJ was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
total:1
Expression, localisation and hormone regulation of the human copper transporter hCTR1 in placenta and choriocarcinoma Jeg-3 cells. 2006 to the paper
Dr J.F. Monty anti-hCTR1 antibody was used in western blot and immnohistochemistry to study the expression, localization, and hormone regulation of the human copper transporter hCTR1 in placenta and choriocarcinoma Jeg-3 cells.
total:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 to the paper
Proteintech rabbit anti-RUVBL1 antibody was used for western blot in order to investigate the role of ILK in the regulation of mitotic spindle organization. more
total:4
Endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly. 2007 to the paper
Stressgen anti-ERp57 Ab (1:2000 dilution) was used western blot to study the role of endoplasmic reticulum chaperones on nicotinic receptor subunits and assembly more
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
total:1
NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. 2009 to the paper
Genway anti-NBA1 antibody (hspc142, catalog no. 15-288-22374A) was used in western blot and immunocytochemistry to study the role for NBA1 in IR resistance, cell cycle regulation, and the recruitment of BRCA1 to sites of DNA damage.
total:11
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smad5 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:4
Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. 2008 to the paper
BD Transduction Laboratories mouse rabbit anti-Rch-1 antibody was used in immunocytochemistry in order to define a novel mechanism of synapse-to-nucleus communication via a synaptic Ca2+-sensor protein more
total:1
Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo). 2008 to the paper
ATCC mouse anti-human LHR antibody was used in immunohistochemistry at 1:100 dilution in order to demonstrate that that cyt b5 is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:21
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-OCT4 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:28
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. 2009 to the paper
R&D systems anti-XIAP antibody was used in western blot to investigate the role of PARP-1 in the NF-kB signalling cascade induced by ionizing radiation more
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
total:2
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Bethyl Laboratories anti-BARD1 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:24
Estrogen receptor beta-mediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma. 2009 to the paper
GeneTex mouse monoclonal anti-ER antibody (C14C8) was used in immunohistochemistry, immunocytochemistry, and immunoprecipitation to study the effect of estrogen receptormediated nuclear interaction between IRS-1 and Rad51 on homologous recombination directed DNA repair in medulloblastoma. more
total:2
miR-183 inhibits TGF-beta1-induced apoptosis by downregulation of PDCD4 expression in human hepatocellular carcinoma cells. 2010 to the paper
Proteintech Group anti-PDCD4 antibody (12587-1-AP) was used to perform western blot in order to clarify that miR-183 could inhibit TGF-beta1-induced apoptosis by repressing the PDCD4 expression in human HCC cells. more
total:15
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Cell Signaling Technologies anti-PRKAA1 antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:1
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. 2006 to the paper
Clonegene Dicer antibody was used in immunohistochemistry to detect Dicer expression in benign human prostate epithelium and neoplastic prostate tissue, in western blot to examine Dicer expression in RWPE-1 and DU145 human prostate cancer cell lines, and in immunocytochemistry to detect Dicer expression in DU145 cell line.
total:3
PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15. 2009 to the paper
Santa Cruz Biotechnology anti-PEA-15 antibody (H-80) was used in western blot to investigate whether the PI3K/PTEN pathway may be important in regulating Fas-induced apoptosis in type I and type II cells. more
total:3
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SAE2 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:9
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-EGF antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more