nucleosomes
gene
reagent
sample publication
sample review
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
total:36
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Bethyl Laboratories anti-histone H4 antibody was used to perform ChIP assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:7
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
MBL International mouse anti-CenpA antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:2
FACT facilitates chromatin transcription by RNA polymerases I and III. 2009 to the paper
Abcam anti-SSRP1 was used to perform immunoprecipitation in order to to determine whether indeed FACT associates with Pol I complexes. more
total:3
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
Santa Cruz Biotechnology anti-CAF-1 p150 was used to perform immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3. more
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:6
Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. 2011 to the paper
Abcam anti-dimethylated H3K9 antibody was used to perform ChIP in order to reveal the link between Clr4 and RNA quality control machinery. more
total:12
Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. 2010 to the paper
Santa Cruz Biotechnology anti-Crem antibody was used to perform western blot and immunoprecipitation in order to study the role of Jmjd1a-controlled epigenetic histone modifications in Crem-regulated gene expression and spermatogenesis. more
total:1
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
Santa Cruz Biotechnology anti-CAF-1 p60 was used to perform immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3.
total:2
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. 2008 to the paper
Proteintech Group anti-BAF53a antibody used to perform immunoprecipitation in order to study the association between the SWI/SNF chromatin-remodeling complexes and the hepatic lipid metabolism. more
total:17
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Millipore rabbit anti-pHH3 was used at 1:500 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:2
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-BAF180 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:4
Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. 2006 to the paper
Michael Bustin (National Institutes of Health) anti-HMGN1 antibody was used in immunohistochemistry to study the expression relationship between HMGN1 and Sox9. more
total:1
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. 2010 to the paper
Abcam mouse anti-CHD1L antibody (1:50) was used in immunohistochemistry in order to study the CHD1L-ARHGEF9-Cdc42-EMT pathway involved in hepatocellular carcinoma (HCC) progression and metastasis.
total:8
The polycomb repressive complex 2 is a potential target of SUMO modifications. 2008 to the paper
Upstate rabbit anti-RbAp48 13D10 was used to perform western blot in order to show that the polycomb repressive complex 2 could be sumoylated post-translationally. more
total:19
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-Ku70 antibody was used to perform immunoblotting in order to studythe role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:13
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB4 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:4
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Bethyl Laboratories SNF2H antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:1
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
ProteinTech Group anti-NASP was used to perform western-blot in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3.
total:4
Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones.. 2010 to the paper
Millipore anti-H4cit 3 antibody was used to perform western blot in order to study the role of PAD2 in citrullination of canine mammary epithelial cell histones. more
total:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 to the paper
Proteintech rabbit anti-RUVBL1 antibody was used for western blot in order to investigate the role of ILK in the regulation of mitotic spindle organization. more
total:6
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. 2006 to the paper
Abcam RbAp46 antibody was used in immunoprecipitation to study the molecular mechanism (s) by which CTIP2 contributes to T cell development and axonal. more
total:22
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Life Technologies anti-Ku80 antibody was used to perform immunoprecipitation and immunofluorescence in order to study IRF-3-dependent innate immunity. more
total:175
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-PARP1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:4
MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing. 2005 to the paper
Upstate Biotechnology anti-Mi2 antibody was used in western blot to study that MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing. more
total:3
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-histone H1 antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:12
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Millipore anti-DNA-PKcs antibody was used to perform western blot and immunofluorescence in order to study IRF-3-dependent innate immunity more
total:1
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. 2008 to the paper
Bethyl anti-DOT1L antibody (A300-954A or 953A) was used in ChIP assay to study the recruitment of DOT1L and the patterning of mono-, di-, and trimethylation of H3K79 under dynamic conditions in human HEK293T cells.
total:14
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
Santa Cruz Biotechnology anti-DAXX was used to perform western-blot and immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3. more
total:1
p400 is required for E1A to promote apoptosis. 2005 to the paper
Santa Cruz Biotechnology anti-E1A antibody was used in western blot and immunoprecipitation to study that p400 is required for E1A to promote apoptosis.
total:8
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB1 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:2
A phosphorylation-acetylation switch regulates STAT1 signaling. 2009 to the paper
Santa Cruz Biotechnology GCN5 antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling. more
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:5
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Millipore anti-HP1beta was used to perform immunocytochemistry in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:4
Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium. 2009 to the paper
Santa Cruz FOXA1 antibody was used in western blot and immunohistochemistry to incubate membranes in order to investigate the role of TEAD1 and its cofactors YAP65 and FOXA2 in the regulation of the dysgenesis of the pigment epithelium. more
total:84
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Santa Cruz anti-PCNA was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3a antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:1
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-DDB2 antibody was used to perform western blot in order to study the DNA damage and response by UV.
total:3
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Upstate rabbit anti-CoREST antibody was used to carry out western blot analysis in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
total:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Upstate Biotechnology anti-MLL antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis. more
total:9
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-SUZ12 antibody was used to carry out ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
total:7
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Santa Cruz anti-HP1 antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:15
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-PCAF antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:14
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. 2009 to the paper
Santa Cruz Biotechnology anti-Tip60 antibody was used in western blot in order to explain that PDCD5 can maintain the histone acetyltransferase activity of the Tip60 protein and promote DNA damage-induced apoptosis as a Tip60 coactivator. more
total:4
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-LSD1 antibody was used to carry out immunoprecipitation assay and ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3b antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:11
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK9 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:24
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. 2009 to the paper
Abcam anti-HDAC2 antibody was used to perform immunohistochemistry in order to study the association between the high class I HDAC activity and RelA/p65 activation in pancreatic cancer. more
total:11
Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. 2010 to the paper
Zymed anti-NPM antibody was used for western blot in order to investigate the role for activated Bax in the regulation of p53-dependent, transcription-independent neural precursor cell apoptosis. more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more