neuroblastoma
gene
reagent
sample publication
sample review
total:7
Lysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomas. 2009 to the paper
Santa Cruz Biotechnology MYCN antibody was used to perform western blot in order to investigate the relations between LAPTM5 and spontaneous regression of neuroblastomas more
total:7
The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL. 2009 to the paper
Zymed Laboratories mouse anti-ALK (1:4000, 4C5B8) antibody was used to study the role of ALK in the pathogenesis and the treatment of anaplastic large cell lymphoma. more
total:27
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Upstate anti-TrkA antibody (06-574, 1:100) was used to perform immunostaining in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:7
Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. 2008 to the paper
BD Biosciences mouse anti-TrkB antibody was used in western blot in order to study the pathogenesis of Joubert syndrome and the role of the Ahi1-Hap1 complex in early brain development more
total:2
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Bethyl Laboratories anti-BARD1 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:3
M(1) and M(2) muscarinic acetylcholine receptor subtypes mediate Ca(2+) channel current inhibition in rat sympathetic stellate ganglion neurons. 2006 to the paper
Chemicon International rabbit anti-M1 antibody (1:200) was used in immunocytochemistry to study the role of M (1) and M (2) muscarinic acetylcholine receptor subtypes in mediating Ca (2+) channel current inhibition in rat sympathetic stellate ganglion neurons. more
total:4
Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7. 2009 to the paper
BD Biosciences anti-UbcH7 antibody was used to perform immunohistochemistry in order to study the regulation of ubiquitin-conjugating enzyme H7 in S phase of the cell cycle. more
total:4
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-DJ-1 antibody was used to perform western blot in order to show that Nrf2 can be stabilized by DJ-1. more
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:1
Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. 2005 to the paper
Dr. Robert T. Jensen anti-GRP-R antibody was used in immunohistochemistry to study the role of neuromedin B and its receptor in both normal and malignant epithelial cells lining the colon.
total:25
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Abcam anti-Tyrosine Hydroxylase antibody (ab6211) was used to perform immunohistochemistry in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:12
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Chemicon rabbit anti-APP C-terminal antibody and mouse anti-APP (6E10) antibody were used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:1
Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons. 2008 to the paper
J-F. Brunet rabbit Phox2b antibody (1:1000) was used in immunohistochemistry in order to demonstrate that Hand2 is a multifunctional DNA binding protein affecting differentiation and cell type-specific gene expression in neural crest-derived noradrenergic sympathetic ganglion neurons
total:1
The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters. 2008 to the paper
BD Biosciences protein tyrosine phosphatase antibody kit was used in western blot in order to study the function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
total:4
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-LSD1 antibody was used to carry out immunoprecipitation assay and ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:33
Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. 2008 to the paper
Santa Cruz Biotechnology anti-alpha-syn mAb211 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:18
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.. 2013 to the paper
Cell Signaling rabbit anti-mFOXO3(phospho-S252)/hFOXO3(phospho-S253) antibody was used to perform western blot in order to investigate the regulatory effect of calcineurin and CAMKII on the lifespan of Caenorhabditis elegans. more
total:45
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Proteintech Group MAPT antibody (1:1500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:17
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Chemicon anti-Prion Protein was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
total:2
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Bethyl rabbit anti-REST antibody was used to carry out western blot analysis in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
total:8
Hepatoblast and mesenchymal cell-specific gene-expression in fetal rat liver and in cultured fetal rat liver cells. 2009 to the paper
Reliatech rabbit polyclonal anti-Prox1 antibody was used to carry out immunofluorescence assays in order to determine whether passaged rat fetal liver cells are functional hepatoblasts. more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:13
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-SIRT1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:4
Inhibition of mitochondrial fusion by ?-synuclein is rescued by PINK1, Parkin and DJ-1. 2010 to the paper
Novus Biologicals polyclonal anti-PINK1 antibody was used to perform immunoblotting in order to study the influence of PINK1, parkin and DJ-1 on alpha-synuclein-mediated inhibition of mitochondrial fusion. more
total:102
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 to the paper
Santa Cruz anti-BAX was used to perform western blot in order to show that chemotherapy is efficient for patients with high mitochondrial priming more
total:8
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Abcam rabbit anti-nm23 antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells. more
total:3
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 to the paper
Abcam goat anti-human Dkk-3 anti-body was used to perform immunohistochemistry in order to investigate the expression alteration of dickkopfs (Dkks) and kremen2 (Krm2) in gastrointestinal cancer. more
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
total:19
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-Ku70 antibody was used to perform immunoblotting in order to studythe role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
total:9
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-BACE1 was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:2
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. 2005 to the paper
Incstar rabbit anti-OPRM1 antibody was used in western blot to detect OPRM1 in CHO cells transfected with wild type and variant OPRM1. more
total:55
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-cyclin E antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Abcam Caspase-3 antibody was used to perform immunohistochemistry in order to study theeffect of thiabendazole on proliferation and apoptosis of human cells. more
total:21
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-OCT4 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:15
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Acris anti-MMP14(113-5B7) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
total:2
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. 2008 to the paper
Abcam rabbit anti-KLF4 antibody 1:15,000 was used for western blot in order to investigate the role of eIF4GI in the regulation of cell proliferation and autophagy. more
total:16
An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans. 2009 to the paper
Stressgen anti-SOD1 antibody was used in western blot in order to demonstrate that locomotor defect associated with aggregation can be found in an ALS-linked mutant SOD1. more
total:44
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Millipore anti-CDK4 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:1
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. 2006 to the paper
Clonegene Dicer antibody was used in immunohistochemistry to detect Dicer expression in benign human prostate epithelium and neoplastic prostate tissue, in western blot to examine Dicer expression in RWPE-1 and DU145 human prostate cancer cell lines, and in immunocytochemistry to detect Dicer expression in DU145 cell line.
total:8
Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activity. 2013 to the paper
R&D systems monoclonal anti-mouse SHH N-term peptide antibody and biotinylated anti-mouse SHH antibody were used to perform ELISA in order to investigate the role of CDON in regulating tumor cell survival. more
total:28
Monocyte 15-lipoxygenase gene expression requires ERK1/2 MAPK activity. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-human Egr-1 antibody was used to perform immunoblotting in order to study the important role of ERK1/2 in mediating IL-13-induced monocyte 15-LO expression. more
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:7
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
Upstate Biotechnology anti-Bmi-1 antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more
total:9
Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha. 2010 to the paper
Novus Biologicals HIF2alpha antibody was used for ChIP assays in order to study HIF-binding and Ets-binding motifs on the PTPRZ1 promoter and show that PTPRZ1 can be activated by HIF-2. more
total:11
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. 2006 to the paper
Santa Cruz Biotechology anti-p110 gamma antibody was used in western blot in order to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation. more
total:10
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
Stressgen anti-HO-1 antibody (1:500) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:37
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Santa Cruz E2F1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:4
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism. 2007 to the paper
Novus anti-FIH was used in western blot to investigate the interaction between ASB4 and FIH in human HEK-293T cells. more
total:8
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. 2006 to the paper
Santa Cruz Biotechnology goat anti-Ret51 antibody was used in western blot and immunoprecipitation to demonstrate that lipid rafts sequester Ret away from the degradation machinery to sustain Ret signaling. more
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:6
Endothelin A receptor blockade influences apoptosis and cellular proliferation in the developing rat kidney. 2009 to the paper
Oncogene antibodies against clusterin were used in western blot to investigate the role of endothelin systems in the regulation of physiologic renal growth and development. more
total:21
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Bethyl Laboratories anti-p73 was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more