neoplasm metastasis
gene
reagent
sample publication
sample review
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:3
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
Santa Cruz Biotechnology anti-Twist monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
total:8
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Abcam rabbit anti-nm23 antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells. more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:27
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 2012 to the paper
Cell Signaling anti-Ezrin antibody was used to perform immunoprecipitation in order to study NKCC1 modulation of glioma cell migration. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:4
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
Santa Cruz Biotechnology anti-Snail1 was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:4
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling. 2007 to the paper
Lab Vision S100A4 antibody was used in western blot to report an increase in S100A6 protein level in colon and lung cancer cells postexposure to ionizing radiation. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:1
Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. 2006 to the paper
Abnova BRMS1 antibody was used in western blot and immunoprecipitation to study the role of BRMS1 in the metastasis of breast cancer.
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:2
Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. 2009 to the paper
Abnova anti-NDRG1 (H00010397M03) antibody was used to perform western blot, flow cytometry, and immunohistochemistry/immunocytochemistry in order to study the altered expression levels of metastasis-related plasma membrane proteins of human breast cancer cells. more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:19
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 to the paper
Spring Bioscience anti SMA antibody (1:100) was used to perform immunohistochemistry in order to study the function of pAkt on posterior capsule. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
total:3
Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer. 2008 to the paper
Abcam anti-KiSS1 antibody was used in western blot to study the effect of the large isoform of MRJ (DNAJB6) on malignant activity of breast cancer. more
total:23
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-p120-catenin antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:60
Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature. 2009 to the paper
Epitomics anti-calveolin-1 antibody was used for immunohistochemistry in order to show that a novel translocation involving chromosome 19 causes Xp11.2 translocation renal cell carcinoma. more
total:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoC antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:8
Clues to CD2-associated protein involvement in cytokinesis. 2005 to the paper
Santa Cruz Biotechnology monoclonal antibody against anti-Rho GDI (A20) was used in western blot to present several clues for the involvement of CD2AP in cytokinesis. more
total:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Santa Curz anit-ROCK1 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
total:51
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 to the paper
Zymed Smad3 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer. more
total:1
MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization. 2009 to the paper
MBL International Corp. mouse anti-human RECK antibody was used in flow cytometry in order to study the role of MT1-MMP and RECK for the motility, adhesion, and mobilization of human hematopoietic progenitor cells.
total:4
ZEB-1, a repressor of the semaphorin 3F tumor suppressor gene in lung cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-ZEB-1 antibody was used for western blot in order to suggest that ZEB-1 can inhibit semaphorin 3F tumor suppressor gene in lung cancer cells. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:4
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
R&D Wnt5A antibody was used to perform western blot in order to investigate the effection of Wnt5A to ROR2 more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:2
Btbd7 regulates epithelial cell dynamics and branching morphogenesis. 2010 to the paper
Santa Cruz Biotechnology anti-Snail2 antibody was used to carry out immunofluorescence assays in order to investigate the role for Btbd7 in promoting epithelial tissue remodeling and branching morphogenesis. more
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:1
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells. 2005 to the paper
Abcam anti-gravin antibody was used in western blot to detect gravin in HEK cells subject to knockdown of either PDE4D or PDE4B.
total:9
Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. 2010 to the paper
Santa Cruz Biotechnology Inc anti-p130CAS antibody was used for immunoblotting in order to illustrate the mechanism of silencing SCARA5 in HCC tumorigenesis and metastasis. more
total:3
GAS6/AXL axis regulates prostate cancer invasion, proliferation, and survival in the bone marrow niche. 2010 to the paper
R&D System anti-AXL antibody was used to perform flow cytometry in order to study the regulatory function of GAS6/AXL axis in bone marrow niche. more
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
total:13
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Santa Cruz Biotechnology anti-EphA2 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:3
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Spring Bioscience anti-D4-GDI polyclonal antibody (1:1,000) was used to perform immunoblot in order to study the Rho GDP dissociation inhibitor 2 (RhoGDI2) suppressed metastasis through Rho GTPases. more
total:1
Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice. 2010 to the paper
R&D Systems biotinylated anti-human Plexin D1 antibody was used to perform western blot and immunohistochemistry in order to study the function of sema3E-plexin D1.
total:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 to the paper
Santa Cruz Biotechnology Tiam1 antibody (C-16) was used to perform co-immunoprecipitation analyse and chromatin immunoprecipitation assays in order to demonstrate the mechanism between Rac1 and the canonical Wnt signalling pathway in colorectal cancer cells. more
total:13
Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. 2009 to the paper
Santa Cruz anti-Ets-1 antibody was used in western blot in order to identify factors for reactivating latent HIV-1 without inducing global T cell activation more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:5
Increased expression of stathmin in eutopic endometrium of patients with endometriosis. 2010 to the paper
Abcam polyclonal rabbit anti-human stathmin antibody was used to perform western blot and immunohistochemistry in order to study the overexpression of stathmin protein in eutopic endometrium of patients with endometriosis. more
total:1
N-acetylglucosaminyltransferase V and beta1-6 branching N-linked oligosaccharides are associated with good prognosis of patients with bladder cancer. 2006 to the paper
Monoclonal antibody against human GnT-V SKNTDFFIGKPTILRELTS (Chikara Ohyama, Department of Urology, Hirosaki University School of Medicine) was used in immunohistochemistry to examine the relationship between GnT-V expression and clinicopathologic features of the patients with bladder cancer.
total:2
Human galectin-2: nuclear presence in vitro and its modulation by quiescence/stress factors. 2008 to the paper
Vector Laboratories monoclonal anti-galectins-1 antibody was used to perform immunocytochemistry in order to study the in vitro nuclear presence and modulation of human galectin-2. more
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:15
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Acris anti-MMP14(113-5B7) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
total:6
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys. 2008 to the paper
Neomarkers anti-Fascin antibody was used to perform immunohistochemistry in order to study the determinants of the level of viremia in naturally SIV-infected SMs. more
total:1
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz goat Abi antibody (1:2000) was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation.
total:5
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
For exploring the effect of DLC1 on angiogenesis, BD Biosciences anti-DLC1 monoclonal antibody was used for performing immunohistochemistry. more
total:19
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
BD anti-Rab5 antibody was used in immunocytochemistry in order to investigate the mechanism of the autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
total:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 to the paper
Serotec rat anti-EMMPRIN monoclonal antibody (1:200) was used in immunohistochemistry in order to examine potential association between EMMPRIN and MMP-9 expre more
total:76
Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-vimentin (C-20 and H-84, 1:1000) antibody was used to perform western blot in order to study the formation mechanism of tubulin-based microtentacles in detached breast tumor cells. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more