natural killer cells
gene
reagent
sample publication
sample review
KIR3DL1
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
KIR3DS1
killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
KIR2DS4
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
KIR2DS3
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3
KIR2DS5
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5
NKG2D
killer cell lectin like receptor K1
total:5
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
BD Pharmingen monoclonal anti-NKG2D-allophycocyanin antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions can be impaired simultaneously by pathological NKG2D ligand expression. more
KIR2DL5A
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
KIR2DS2
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
KIR2DL1
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
KIR2DS1
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
KIR2DL2
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
KIR2DL4
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
KIR3DL3
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
KIR3DL2
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
NKG2A
killer cell lectin like receptor C1
total:1
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-NKG2A antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses.
MICA
MHC class I polypeptide-related sequence A
total:3
Opposing effects of interferon-alpha and interferon-gamma on the expression of major histocompatibility complex class I chain-related A in tumors. 2008 to the paper
R&D Systems anti-MICA antibody was used to perform flow cytometry in order to study the differential effects of IFN-alpha and IFN-gamma on tumor cells. more
IL-15
interleukin 15
total:7
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. 2009 to the paper
R&D Systems anti-human IL-15R antibody was used to perform enzyme-linked immunosorbent assays in order to investigate the relationship between IL-15R and specific immune response. more
HLA-C
major histocompatibility complex, class I, C
total:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 to the paper
Invitrogen Purified goat IgG was used as the isotypic controls in order to identify the MHC I molecule (HLA-C) as an attachment factor in facilitating HCoV-HKU1 spike (S) mediated infection. more
NCR1
natural cytotoxicity triggering receptor 1
total:3
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
Beckman Coulter monoclonal anti-NKp46-PE antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions were impaired simultaneously by pathological NKG2D ligand expression. more
NCR3
natural cytotoxicity triggering receptor 3
total:2
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
Beckman Coulter monoclonal anti-NKp30-PE antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions were impaired simultaneously by pathological NKG2D ligand expression. more
MICB
MHC class I polypeptide-related sequence B
total:1
Opposing effects of interferon-alpha and interferon-gamma on the expression of major histocompatibility complex class I chain-related A in tumors. 2008 to the paper
R&D Systems anti-MICB antibody was used to perform flow cytometry in order to study the differential effects of IFN-alpha and IFN-gamma on tumor cells.
KIR2DL5B
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B
CD1D
CD1d molecule
total:5
A novel IL-17-dependent mechanism of cross protection: respiratory infection with mycoplasma protects against a secondary listeria infection. 2009 to the paper
BD PharMingen anti-NK1.1 antibody was used in flow cytometry in order to investigate the role of IL-17 in the regulation of Listeria infection. more
RAET1G
retinoic acid early transcript 1G
total:1
Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G. 2009 to the paper
BD Transduction Labs rabbit polyclonal anti-RAET1G antibody was used in western blot in order to characterize the two isoforms of ULBP5/RAET1G and study their cellular expression and trafficking.
NCR2
natural cytotoxicity triggering receptor 2
CD16
Fc fragment of IgG receptor IIIa
total:42
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD16 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
HLA B
major histocompatibility complex, class I, B
total:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
PharMingen anti-HLA-B antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes
LILRB1
leukocyte immunoglobulin like receptor B1
total:2
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Upstate CD85j antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo. more
CD244
CD244 molecule
total:2
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. 2009 to the paper
eBioscience, CD244 antibody was used for flow cytometry in order to clarify that ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. more
ULBP3
UL16 binding protein 3
total:1
Opposing effects of interferon-alpha and interferon-gamma on the expression of major histocompatibility complex class I chain-related A in tumors. 2008 to the paper
R&D Systems anti-ULBP3 antibody was used to perform flow cytometry in order to study the differential effects of IFN-alpha and IFN-gamma on tumor cells.
granzyme B
total:4
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
Santa Cruz Biotechnology mouse anti-granzyme B monoclonal antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for IL-33 in promoting allergic inflammation. more
HLA-A
major histocompatibility complex, class I, A
total:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 to the paper
Santa Cruz Biotechnology anti-HLA-A(A-18) antibody was used to perform immunohistochemistry in order to study tumor and tumor-stromal cell interactions. more
CD56
neural cell adhesion molecule 1
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
perforin
perforin 1
total:9
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. 2011 to the paper
Biolegend anti-perforin antibody was used to perform immunocytochemistry in order to study the secretion of natural killer cell lytic granule at the immune synapse. more
interleukin 2
total:17
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-2 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
HLA E
major histocompatibility complex, class I, E
total:12
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Serotec FITC-conjugated anti-MHC-I was used to perform flow cytometry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
KLRB1
killer cell lectin like receptor B1
total:6
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD161 was used in 5ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
IL-18
interleukin 18
total:7
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-18 antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
IFN-gamma
interferon gamma
total:62
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IFN-gamma was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
IL12B
interleukin 12B
total:2
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-12 (p40) antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
CD1a
CD1a molecule
total:15
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
BD Pharmingen anti-CD1a-FITC was used to perform flow cytometry in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more