multiple myeloma
gene
reagent
sample publication
sample review
total:1
Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray. 2005 to the paper
LICR antibody against CT7 (CT7-33) was used in immunohistochemistry to investigate the distribution of CT7 (MAGE-C1) among different types and grades of human endometrial carcinomas.
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:2
Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. 2005 to the paper
R&D Systems anti BCMA antibody was used in western blot and flow cytometry to study graft-versus-tumor response in patients with multiple myeloma more
total:6
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. 2008 to the paper
Alexis monoclonal anti-BAFF antibody (804-131-C100, Buffy-2 clone) was used in immunohistochemistry to study the expression of BAFF and APRIL in breast cancer in paraffin sections from human tumor. more
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
total:31
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Calbiochem anti-Bim antibody was used to perform immunoprecipitation in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 to the paper
Zymed rabbit anti-Cks1 (C-term) antibody was used in western blot to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:3
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
BioLegend anti-XBP1s antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
total:2
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. 2008 to the paper
Alexis mouse monoclonal anti-APRIL (hAprily-8) antibody (ALX-804-149) was used in immunohistochemistry to study the expression of BAFF and APRIL in breast cancer in paraffin sections from human tumor. more
total:7
Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils. 2007 to the paper
R&D Systems monoclonal anti-human OPG antibody was used in elisa to study differential expression of RANK, RANK-L, and osteoprotegerin from patients with rheumatoid arthritis. more
total:11
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
New England Biolabs anti-p52/p100 (18D10) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:3
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. 2009 to the paper
Peprotech EC biotinylated polyclonal goat anti-human TACI antibody was used to carry out flow cytometry analysis in order to evaluate the genetic, immunologic, and clinical condition of patients with different TNFRSF13B variants. more
total:6
Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma. 2009 to the paper
Dako anti-MUM-1/IRF4 antibody (clone:MUM1P) was used in immunohistochemistry to analyze the expression pattern of MUM1, bcl-6, and CD138 along with the association of EBV in 222 well-characterized cases of BL. more
total:2
SUMO conjugation contributes to immune deviation in nonobese diabetic mice by suppressing c-Maf transactivation of IL-4. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-c-Maf (M-153) antibody was used to perform immunoprecipitation and western blotting in order to demonstrate that sumoylation of c-Maf by SUMO-1 reduces its transactivational capacity of IL-4. more
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
total:5
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 to the paper
Abcam goat anti-human Dkk-1 anti-body was used to perform immunohistochemistry in order to investigate the expression alteration of dickkopfs (Dkks) and kremen2 (Krm2) in gastrointestinal cancer. more
total:1
Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray. 2005 to the paper
LICR antibody against MAGE-A3 (M3H67) was used in immunohistochemistry to investigate the distribution of MAGE-A3 among different types and grades of human endometrial carcinomas.
total:1
Targeted degradation of the AML1/MDS1/EVI1 oncoprotein by arsenic trioxide. 2006 to the paper
Santa Cruz Biotechnology anti-Blimp-1 antibody was used in western blot to determine whether ATO could target AME and related oncoproteins.
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:9
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
R&D Systems monoclonal anti-human HGF antibody (MoAb) was used in blocking or activating expriments to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
total:123
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-Cyclin D1 antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:10
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
Santa Cruz Biotechnology anti-gp80 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more
total:7
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. 2009 to the paper
eBioscience antibodies against alpha4beta1 were used in immunohistochemistry to investigate MuPAR and plasmin in the regulation of the proliferation, marrow pool size, homing, engraftment, and mobilization of HSPCs and HSCs. more
total:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:34
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Santa Cruz Biotechnology anti-Mcl-1 antibody was used to perform western blot in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:9
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. 2006 to the paper
R & D Systems anti-caspase-10 antibody was used in human THP-1 cells and in western blot to study the roles for the interaction of the B30.2 domain of pyrin, the familial mediterranean fever protein with caspase-1 in IL-1 production. more
total:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-cytochrome c antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:117
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
Santa Cruz anti-I-kappa B alpha antibody was used to perform western blot in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:5
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
BD Pharmingen monoclonal anti-NKG2D-allophycocyanin antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions can be impaired simultaneously by pathological NKG2D ligand expression. more
total:10
Proteomic analysis of purified coronavirus infectious bronchitis virus particles. 2010 to the paper
Abcam rabbit polyclonal annexin A2 antibody (ab40943) was used to perform western blot in order to investigate proteomic profile of infectious bronchitis virus. more
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more
total:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 to the paper
R&D Systems sandwich ELISA kit in which mouse anti-human OPG was employed as capture antibody and a biotinylated goat anti-human OPG used for detection to determine the concentration of OPG in the conditional medium of human vascular smooth muscle cells. more
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:6
Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. 2013 to the paper
Abcam anti-YB-1 antibody was used to perform western blotting in order to determine the subcellular distribution of the hnRNP-Q. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:5
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression. 2008 to the paper
Dako anti-B2m was used to perform immunohistochemistry in order to study the presence of specific populations of tumor infiltrating lymphocytes in diagnostic primary melanoma biopsies are associated with outcome in clinically stage II melanoma patients. more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:19
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
eBioscience anti-IL-17A mAb was used to perform flow cytometry and cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:17
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Epitomics anti-Notch1 antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 to the paper
Immunotech anti-VCAM-1 antibody was used in blocking or activating expriments to study the role for prostate specific membrane antigen in regulating the expression of IL-6 and CCL5 in prostate tumour cells. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:85
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Santa Cruz Biotechnology mouse anti-Bcl-XL monoclonal antibody was used to perform western blot in order to study the function of the natural product honokiol. more
total:6
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-TRAIL antibody was used in western blot to investigate the role of human BVR in sodium arsenite (As) mediated induction of HO-1 and in cytoprotection against apoptosis by small interference RNA-mediated gene silencing. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:21
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Abcam anti-collagen I antibody was used to perform immunohistochemistry and immunocytochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:11
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum. 2009 to the paper
Chemicon International antibodies against BDNF was used in immunohistochemistry in order to confirm the differential expression of neurotrophins in postnatal C57BL/6 mice striatum. more
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:40
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Santa Cruz Biotechnology PE-conjugated anti-IGF-1R antibody was used in flow cytometry to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:34
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
Upstate anti-JAK2 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:30
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-1-beta mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
total:9
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. 2009 to the paper
Sigma mouse GG-7 Fc-specific anti-human IgG antibody was used to confirm the presence of the Fc fragment of human IgG in order to illustrate that Toll-like receptor 4 (TLR4) plays a fundamental role in the sensing of LPS from Gram-negative bacteria. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more