mitotic spindle apparatus
gene
reagent
sample publication
sample review
Mad2
mitotic arrest deficient 2 like 1
total:11
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
Immuquest anti-MAD2 antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
CDC20
cell division cycle 20
total:6
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-p55CDC antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
total:6
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
BD Transduction Laboratories anti-BUB1B antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
Plk1
polo like kinase 1
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
AIM-1
aurora kinase B
total:23
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Rockland anti-pT232 Aurora B was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
AURKA
aurora kinase A
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
CDC27
cell division cycle 27
total:8
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Abcam anti-CDC27 antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation. more
NUMA1
nuclear mitotic apparatus protein 1
total:4
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 to the paper
Santa Cruz Biotechnology goat anti-NuMA polyclonal antibody was used to perform western blot and immunoprecipitation assays in order to demonstrate that the interaction of NuMA with LANA plays a great role in KSHV genome maintenance and segregation. more
NDC80
NDC80 kinetochore complex component
total:4
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-Hec1 antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
TACC3
transforming acidic coiled-coil containing protein 3
total:2
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
USBiological goat anti-TACC3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
TTK
TTK protein kinase
total:1
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. 2005 to the paper
Santa Cruz anti-TTK antibody (sc-540) was used in human cells and in immunoprecipitation, western blot to study the role for the effect of TTK/hMps1 on CHK2 in the regulation of DNA damage checkpoint.
KIF2C
kinesin family member 2C
total:1
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Abnova mouse monoclonal anti-MCAK antibody was used to carry out immunoblotting assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres.
NEDD1
NEDD1 gamma-tubulin ring complex targeting factor
MAD1L1
mitotic arrest deficient 1 like 1
total:2
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1. 2008 to the paper
Santa Cruz Biotechnology anti-mad1 antibody was used for western blot in order to investigate the roles of PI3K/Akt and MAPK pathways in the regulation of Myc-mediated transcription more
CENPE
centromere protein E
total:3
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Abcam monoclonal anti-CENP-E antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
AURKAIP1
aurora kinase A interacting protein 1
BUB3
BUB3 mitotic checkpoint protein
total:2
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
BD Transduction Laboratories monoclonal anti-BUB3 antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
BUB1
BUB1 mitotic checkpoint serine/threonine kinase
total:2
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Chemicon mouse monoclonal anti-Bub1 antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
CKAP5
cytoskeleton associated protein 5
ZW10
zw10 kinetochore protein
total:2
A mammalian NudC-like protein essential for dynein stability and cell viability. 2006 to the paper
Antibodies anti-CREST antibody was used in western blot in order to demonstrate that NudC-like protein (NudCL) plays an essential role in mitosis and contributes to stabilization of the dynein complex. more
HAUS5
HAUS augmin like complex subunit 5
HAUS3
HAUS augmin like complex subunit 3
cyclin B1
total:64
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Thermo Fisher Scientific anti-cyclin B1 monoclonal antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
CLASP1
cytoplasmic linker associated protein 1
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
PRC1
protein regulator of cytokinesis 1
total:1
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. 2009 to the paper
Santa Cruz Biotechnology PRC1 antibody was used for immunocytochemistry in order to investigate the roles of RanBP2 and SENP3 in the regulation of the SUMOylation of Borealin.
Cdc2
cyclin dependent kinase 1
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
CHFR
checkpoint with forkhead and ring finger domains
TPX2
TPX2 microtubule nucleation factor
total:2
Expression of selected Aurora A kinase substrates in solely estrogen-induced ectopic uterine stem cell tumors in the Syrian hamster kidney. 2008 to the paper
Santa Cruz anti-TPX2 antibody was used to perform western blot in order to study the expression of Aurora A kinase substrates in estrogen-induced ectopic uterine stem cell tumors. more
NEK6
NIMA related kinase 6
total:2
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. 2008 to the paper
Abgent anti-human NEK6 was used to perform western blot in dilution 1:500 in order to show that differentially overexpressed genes in gastric cancer are revealed by combining large-scale gene expression profiling and network analysis. more
Ran
RAN, member RAS oncogene family
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
cyclin A
cyclin A2
total:39
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-cyclin A antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
DYNLL1
dynein light chain LC8-type 1
total:3
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. 2009 to the paper
Abcam monoclonal anti-dynein antibody (74.1ab23905) was used in blocking or activating expriments to study the roles for nudel and dynein in assembly of the lamin B spindle matrix. more
gamma-tubulin
tubulin gamma 1
total:38
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Sigma-Aldrich rabbit anti-gamma tubulin was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
UBE2C
ubiquitin conjugating enzyme E2 C
total:3
Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7. 2009 to the paper
Boston Biochem anti-UbcH10 antibody was used to perform immunohistochemistry in order to study the regulation of ubiquitin-conjugating enzyme H7 in S phase of the cell cycle. more
CDK5RAP2
CDK5 regulatory subunit associated protein 2
RCC1
regulator of chromosome condensation 1
total:3
A survivin-ran complex regulates spindle formation in tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-human RCC1 antibody was used to perform western blot in order to study the role of survivin-Ran signaling in spindle formation in tumor cells. more
SKA3
spindle and kinetochore associated complex subunit 3
INCENP
inner centromere protein
total:6
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Santa Cruz Biotechnology anti-inner centromeric protein antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
NDE1
nudE neurodevelopment protein 1
total:1
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Proteintech Group rabbit anti-Nde1 antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation.