mitochondrial membranes
gene
reagent
sample publication
sample review
Bax
BCL2 associated X, apoptosis regulator
total:102
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 to the paper
Santa Cruz anti-BAX was used to perform western blot in order to show that chemotherapy is efficient for patients with high mitochondrial priming more
MCU
mitochondrial calcium uniporter
total:1
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
Covance polyclonal chicken anti-human MCU antibody was used to perform western blot in order to investigate the functional property of the MCU gene.
TIMM23
translocase of inner mitochondrial membrane 23
total:1
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
BD Biosciences anti-TIMM23 antibody was used to perform western blot in order to investigate the functional property of the MCU gene.
VDAC1
voltage dependent anion channel 1
total:20
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. 2011 to the paper
Abcam anti-porin antibody was used to perform immunoprecipitation in order to reveal how viperin facilitates the infectious process. more
Bid
BH3 interacting domain death agonist
total:35
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 to the paper
Santa Cruz anti-Bid was used to perform western blot in order to show that chemotherapy is efficient for patients with high mitochondrial priming more
DNM1L
dynamin 1 like
total:4
ER tubules mark sites of mitochondrial division. 2011 to the paper
Abcam anti-Dnm1L was used to perform western blot in order to show that mitochondrial fission could be mediated by ER tubules. more
MIA40
coiled-coil-helix-coiled-coil-helix domain containing 4
Bak
BCL2 antagonist/killer 1
total:27
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
Upstate Biotech anti-Bak NT antibody was used to perform immunoprecipitation and western blot in order to study the interactions between Bak and F1L or Mcl1. more
LETM1
leucine zipper and EF-hand containing transmembrane protein 1
TOMM70
translocase of outer mitochondrial membrane 70
Smac
diablo IAP-binding mitochondrial protein
total:16
Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. 2010 to the paper
Calbiochem anti-Smac/DIABLO antibody (1/3000) was used to perform ELISA in order to study the function of cancer cell lines mitochondria in exploring the mechanisms of mitochondrial membrane permeabilization induced by BH3 peptides and ABT-737. more
CYCS
cytochrome c, somatic
total:48
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
BD PharMingen anti-cytochrome c antibody was used to perform western blot in order to study the interaction between F1L and endogenous Bak. more
Bcl 2
BCL2 apoptosis regulator
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
Bcl-xL
BCL2 like 1
total:85
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Santa Cruz Biotechnology mouse anti-Bcl-XL monoclonal antibody was used to perform western blot in order to study the function of the natural product honokiol. more
FIS1
fission, mitochondrial 1
total:1
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
ALEXIS Biochemicals polyclonal anti-Fis1 antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury.
PINK1
PTEN induced kinase 1
total:4
Inhibition of mitochondrial fusion by ?-synuclein is rescued by PINK1, Parkin and DJ-1. 2010 to the paper
Novus Biologicals polyclonal anti-PINK1 antibody was used to perform immunoblotting in order to study the influence of PINK1, parkin and DJ-1 on alpha-synuclein-mediated inhibition of mitochondrial fusion. more
caspase-8
caspase 8
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
MAVS
mitochondrial antiviral signaling protein
total:1
Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria. 2009 to the paper
Cell Signaling Technology rabbit polyclonal anti-VISA antibody was used in western blot to study the effect of gC1qR on RIG-I and MDA5-dependent antiviral response at mitochondria.
PUMA
BCL2 binding component 3
total:12
Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer. 2008 to the paper
Calbiochem anti-PUMA antibody was used in western blot to study the mechanism and effect of p53 activation by a potent and specific MDM2 antagonist (MI-43) in colon cancer. more
Caspase-9
caspase 9
total:75
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-caspase-9 antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
XIAP
X-linked inhibitor of apoptosis
total:28
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. 2009 to the paper
R&D systems anti-XIAP antibody was used in western blot to investigate the role of PARP-1 in the NF-kB signalling cascade induced by ionizing radiation more
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
total:11
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. 2006 to the paper
Santa Cruz Biotechology anti-p110 gamma antibody was used in western blot in order to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation. more
Bip
heat shock protein family A (Hsp70) member 5
total:47
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Abcam GRP78/BiP rabbit polyclonal (1:25) was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
alpha synuclein
synuclein alpha
total:33
Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. 2008 to the paper
Santa Cruz Biotechnology anti-alpha-syn mAb211 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration. more
p53
tumor protein p53
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more