microtubules
gene
reagent
sample publication
sample review
tau
microtubule associated protein tau
total:45
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Proteintech Group MAPT antibody (1:1500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
MAPRE1
microtubule associated protein RP/EB family member 1
total:3
Mammalian end binding proteins control persistent microtubule growth. 2009 to the paper
BD Biosciences anti-EB1 mouse monoclonal antibody was used in immunohistochemistry and western blot in order to show that persistent microtubule growth can be regulated by end binding proteins in mammal. more
NDC80
NDC80 kinetochore complex component
total:4
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-Hec1 antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
AIM-1
aurora kinase B
total:23
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Rockland anti-pT232 Aurora B was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
HDAC6
histone deacetylase 6
total:9
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Santa Cruz rabbit anti-HDAC6 antibody (WB, 1:2000; IF, 1:500) was used to perform western blot and immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
SPAST
spastin
total:1
Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion. 2009 to the paper
Santa Cruz Biotechnology mouse anti-spastin monoclonal antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the role for spastin coupled with microtubule in regulating membrane traffic.
STMN1
stathmin 1
total:5
Increased expression of stathmin in eutopic endometrium of patients with endometriosis. 2010 to the paper
Abcam polyclonal rabbit anti-human stathmin antibody was used to perform western blot and immunohistochemistry in order to study the overexpression of stathmin protein in eutopic endometrium of patients with endometriosis. more
KIF2C
kinesin family member 2C
total:1
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Abnova mouse monoclonal anti-MCAK antibody was used to carry out immunoblotting assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres.
p150Glued
dynactin subunit 1
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
TUBB3
tubulin beta 3 class III
total:37
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Chemicon anti-B-Tubulin antibody was used to perform immunohistochemistry in order to study synaptic plasticity. more
Plk1
polo like kinase 1
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
TUBA1A
tubulin alpha 1a
total:117
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Sigma mouse anti-alpha-tubulin was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
TUBB2B
tubulin beta 2B class IIb
total:4
Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. 2009 to the paper
Santa Cruz Biotech anti tubulin antibody (1:3,000) was used to perform western blot in order to study the rescuing function of human IKBKAP in the embryonic lethality resulting from mouse Ikbkap ablation. more
beta-tubulin
tubulin beta 1 class VI
total:25
Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. 2010 to the paper
Chemicon International mouse anti-beta tubulin antibody was used to carry out western blot analysis in order to investigate elastin-like polypeptide as carrier to target cell cycle inhibitory peptide for inhibiting ovarian cancer cell proliferation. more
SKA1
spindle and kinetochore associated complex subunit 1
KIF5A
kinesin family member 5A
total:1
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. 2005 to the paper
Abcam anti-KIF5A (1007 1027) antibody was used in western blot to characterize GRIF-1 and OIP106 and to study their associaiton with kinesin
PRC1
protein regulator of cytokinesis 1
total:1
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. 2009 to the paper
Santa Cruz Biotechnology PRC1 antibody was used for immunocytochemistry in order to investigate the roles of RanBP2 and SENP3 in the regulation of the SUMOylation of Borealin.
SKA3
spindle and kinetochore associated complex subunit 3
DSN1
DSN1 component of MIS12 kinetochore complex
TBCE
tubulin folding cofactor E
total:1
Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells. 2010 to the paper
Protein-Tech Group anti-TBCE antibody(1:500) was used to perform western blot in order to study the recognition of CML Progenitor Cells expressed antigens by Efficacious Immune Therapy in Chronic Myelogenous Leukemia (CML).
MAP4
microtubule associated protein 4
total:1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 to the paper
BioLegend anti-Map4-P(Ser768) antibody was used to perform western blot and immunohistochemistry in order to study the acinar polarity defects and cystic neoplasms induced by Lkb1-deficient in pancreas.
KIF5B
kinesin family member 5B
total:5
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. 2009 to the paper
Abcam anti-KIF5B antibody ab5629 was used in western blot to study the role for kinesin 5B in cancer cells. more
MAPRE2
microtubule associated protein RP/EB family member 2
total:1
Mammalian end binding proteins control persistent microtubule growth. 2009 to the paper
Absea anti-EB2 rat monoclonal KT52 antibody was used in immunohistochemistry and western blot in order to show that persistent microtubule growth can be regulated by end binding proteins in mammal.
CENPE
centromere protein E
total:3
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Abcam monoclonal anti-CENP-E antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
SCG10
stathmin 2
total:1
Interleukin-6 and neural stem cells: more than gliogenesis. 2009 to the paper
Proteintech Group rabbit polyclonal anti-STMN2 antibody was used to detect STMN2 in western blot in order to demonstrate that the MAPK/CREB cascade and the STAT-3 signaling pathway mediate H-IL-6-activated neurogenesis and gliogenesis
PAFAH1B1
platelet activating factor acetylhydrolase 1b regulatory subunit 1
total:6
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. 2010 to the paper
Sigma anti-LIS1 antibody was uesd to perform western blot in order to study the regulation of the LIS1/dynein pathway by NudC-like protein 2 via stabilizing LIS1 with Hsp90. more
CLASP1
cytoplasmic linker associated protein 1
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
TPPP
tubulin polymerization promoting protein
total:1
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Santa Cruz anti-GSK3 antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction.
Ran
RAN, member RAS oncogene family
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
APC
APC regulator of WNT signaling pathway
total:11
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis. 2009 to the paper
Calbiochem anti-APC was used to perform immunocytochemistry in order to show that MRP protein plays an important role in adherens junction formation and tumorigenesis more
MACF1
microtubule actin crosslinking factor 1
CKAP5
cytoskeleton associated protein 5
AURKA
aurora kinase A
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
TTK
TTK protein kinase
total:1
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. 2005 to the paper
Santa Cruz anti-TTK antibody (sc-540) was used in human cells and in immunoprecipitation, western blot to study the role for the effect of TTK/hMps1 on CHK2 in the regulation of DNA damage checkpoint.
NUMA1
nuclear mitotic apparatus protein 1
total:4
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 to the paper
Santa Cruz Biotechnology goat anti-NuMA polyclonal antibody was used to perform western blot and immunoprecipitation assays in order to demonstrate that the interaction of NuMA with LANA plays a great role in KSHV genome maintenance and segregation. more
gamma-tubulin
tubulin gamma 1
total:38
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Sigma-Aldrich rabbit anti-gamma tubulin was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
DYNC1H1
dynein cytoplasmic 1 heavy chain 1
total:7
Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. 2010 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-rat Dync1h1 antibody was used to perform western blot and immunohistochemistry in order to study the multiple functions of Dynein1 in zebrafish retinal photoreceptor development. more
NUDEL
nudE neurodevelopment protein 1 like 1
total:1
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Sigma-Aldrich anit-VSVG antibody was used to perform immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex.
SKA2
spindle and kinetochore associated complex subunit 2
MAPRE3
microtubule associated protein RP/EB family member 3
total:2
Mammalian end binding proteins control persistent microtubule growth. 2009 to the paper
BD Biosciences anti-EB3 mouse monoclonal antibody was used in immunohistochemistry and western blot in order to show that persistent microtubule growth can be regulated by end binding proteins in mammal. more