metabolic syndrome x
gene
reagent
sample publication
sample review
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:6
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Ob antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Abcam monoclonal anti-C-reactive protein (CRP) antibody was used in immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
total:2
Juvenile dermatomyositis calcifications selectively displayed markers of bone formation. 2009 to the paper
R&D Systems anti-OC antibody was used to carry out immunohistochemistry assays in order to determine the presence of SIBLING protein and bone components in Juvenile Dermatomyositis pathologic calcifications. more
total:1
Quantitation and cellular localization of 11beta-HSD1 expression in murine thymus. 2006 to the paper
Dr. Zygmunt Krozowski (Baker Heart Research Institute) 11beta-HSD1 antibody was used in western blot to assess 11beta-HSD1 protein expression in whole tissues.
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:9
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 to the paper
Santa Cruz Biotechnology OB-R antibodies (C-20: specific for long form of leptin receptor, H-300: for both long and short form of leptin receptor, mouse monoclonal B-3: for both long and short forms of leptin receptor) were used in immunoprecipitation (C-20 and H-300) and western blot (B-3) to study the recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 by leptin and its stimulation of breast cancer cells. more
total:2
Identification of small molecule activators of cryptochrome. 2012 to the paper
Affinity BioReagents anti-CLOCK was used to perform western blot in order to show that cryptochrome could be studied by specific small molecule activators. more
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
total:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-ACE was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:2
Host biomarkers and biological pathways that are associated with the expression of experimental cerebral malaria in mice. 2008 to the paper
Novus Biologicals anti-hemoglobin alpha1 antibody was used in western blot to identify novel host molecules in the brain that are affected in the course of the pathological manifestation of CM. more
total:7
Constitutive overexpression of pigment epithelium-derived factor inhibition of ocular melanoma growth and metastasis. 2010 to the paper
Santa Cruz anti-PEDF antibody was used in western blot to investigate the role of lentivirus-mediated gene transfer of PEDF in the regulation of the growth of ocular melanoma and its hepatic micrometastasis. more
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
total:8
Curcumin suppresses PPARdelta expression and related genes in HT-29 cells. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR5 antibody was used in western blot to investigate the role of curcumin in the regulation of the expression of PPARdelta, 14-3-3epsilon, and VEGF in HT-29 cells. more
total:12
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Santa Cruz Biotechnology anti-GP130 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway. more
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
R&D systems anti-fetuin A antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
total:4
Cannabinoid CB? receptor is downregulated in clear cell renal cell carcinoma. 2010 to the paper
ABR Affinity BioReagents anti-CB1 polyclonal antibody was used to perform western blot and immunohistochemistry in order to study the downregulation of cannabinoid receptor CB1 in clear cell renal carcinoma. more
total:13
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Upstate Irs2 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
total:1
Stimulatory cross-talk between NFAT3 and estrogen receptor in breast cancer cells. 2005 to the paper
Stratagene anti-Lac polyclonal antibody was used in western blot to identify the transcription factor NFAT3 as a new ER-interacting partner in breast cancer cells.
total:2
A 14-kDa cathepsin L-derived carboxyl IGFBP-2 fragment is sequestered by cultured rat ileal crypt cells. 2005 to the paper
Santa Cruz Biotechnology IGFBP2 antibody was used in western blot and immunohistochemistry to demonstrate that dexamethasone alters proteolytic regulation of IGFBP-2 in ileal crypt cells. more
total:5
Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. 2008 to the paper
Calbiochem anti-pan-cadherin antibody was used in western blot in order to identify NS5A-associated target molecules more
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
total:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 to the paper
Upstate Biotechnology anti-TCF-4 antibody was used in immunoprecipitation and western blotting to investigate the action mechanism of the growth inhibition induced by bis[2-(acylamino)phenyl] disulfide. more
total:10
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
Santa Cruz Biotechnology anti-gp80 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more
total:7
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-18 antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
total:12
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. 2011 to the paper
AbD serotec goat-anti-Human-C3 was used to perform ELISA in order to show that HIV glycan coat could be recognized by PGT antibody to neutralize HIV. more
total:37
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. 2011 to the paper
Invitrogen anti-phospho-IRS (Y612) was used to perform western blot in order to show that Grb10 was indentified as a negative regulator of insulin signaling by phosphoproteomic analysis. more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:13
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-CD40L antibody (1:200) was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:6
Suppression of neuroblastoma growth by dipeptidyl peptidase IV: relevance of chemokine regulation and caspase activation. 2009 to the paper
Biomol anti-DPPIV antibody was used to perform immunohistochemistry in order to study the suppression of neuroblastoma growth performed by dipeptidyl peptidase IV. more
total:7
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Santa Cruz Biotechnology anti-ADRB2 C-tail antibody was used to carry out western blot analysis in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 to the paper
Immunotech anti-VCAM-1 antibody was used in blocking or activating expriments to study the role for prostate specific membrane antigen in regulating the expression of IL-6 and CCL5 in prostate tumour cells. more
total:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 to the paper
R&D Systems sandwich ELISA kit in which mouse anti-human OPG was employed as capture antibody and a biotinylated goat anti-human OPG used for detection to determine the concentration of OPG in the conditional medium of human vascular smooth muscle cells. more
total:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz rabbit anti-AT1 was used to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 to the paper
R&D systems rat anti-human ET-1 antibody (3G10) was used in immunohistochemistry to examine the distribution of eNOS and ET-1 in relation to vascular density represented by the endothelial marker CD31-immunoreactivity in skin tissue from amputated limbs of patients with CRPS. more
total:57
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Santa Cruz lamin A/C goat polyclonal (1:1000)was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more