melanoma
gene
reagent
sample publication
sample review
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:1
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. 2005 to the paper
Santa Cruz Biotechnology MC1R antibody (N-19) antibody was used in western blot and immunohistochemistry to study its expression in skin cancer abd red hair persons
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
total:6
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
Lab Vision MART1 antibody was used to perform western blot in order to further explore the relationship between Wnt5A and ROR2 more
total:10
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D mouse anti-pTyr antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 to the paper
Santa Cruz rabbit anti-Galphaq antibody was used in immunocytochemistry to study the effect of the interaction between caveolin-1 and the Galphaq family of G proteins on Ca2+ signal duration. more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:3
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome. 2008 to the paper
Lab Vision mouse monoclonal HMB45 antibody (1:100) was used in immunocytochemistry in order to study the role of Switch I region in the recruitment of Rab effector proteins. more
total:1
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
ProSci ABCB5 antibody (1:2000) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells.
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:1
Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons. 2008 to the paper
Santa Cruz goat Sox10 antibody (1:50) was used in immunohistochemistry in order to demonstrate that Hand2 is a multifunctional DNA binding protein affecting differentiation and cell type-specific gene expression in neural crest-derived noradrenergic sympathetic ganglion neurons
total:2
Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL. 2005 to the paper
Upstate Biotechnology anti-Tyr (P) antibody 4G10 was used in western blot to study the binding of the intracellular Fas Ligand (FasL) domain to the adaptor protein PSTPIP which results in the cytoplasmic localization of FasL. more
total:3
Melanoma Inhibitory Activity (MIA) increases the invasiveness of pancreatic cancer cells. 2005 to the paper
Roche Diagnostic GmbH anti-MIA antibody (which was in ELISA kit) was used in human cells and in ELISA to study the effect of melanoma inhibitory activity (MIA) on the invasiveness of pancreatic cancer cells. more
total:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Santa Cruz Biotechnology mouse monoclonal B-Raf antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines more
total:1
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Developmental Studies Hybridoma Bank mouse monoclonal anti-Pax3 antibody was used in flow cytometry at 1:50 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells
total:2
Selective cancer-germline gene expression in pediatric brain tumors. 2008 to the paper
Zymed mouse monoclonal anti-NY-ESO-1 antibody was used in immunohistochemistry in order to study the expression of 12 CGGs in pediatric brain tumors and to identify targets for therapeutic cancer vaccines more
total:23
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
BD anti-mouse S100B antibody (1:1000) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:12
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Chemicon anti-NG2 antibody (1:1500) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:44
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Millipore anti-CDK4 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:4
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
R&D Wnt5A antibody was used to perform western blot in order to investigate the effection of Wnt5A to ROR2 more
total:2
The core binding factor CBF negatively regulates skeletal muscle terminal differentiation. 2010 to the paper
Abcam anti-trimethyl H3K4 antibody was used to perform chromatin immunoprecipitation in order to study the regulatory effect of core binding factor in skeletal muscle terminal differentiation. more
total:20
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB2 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:7
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
BD Biosciences mGluR1 antibody was used in western blot to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:6
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Upstate rabbit anti-Yes1 (06.514) polyclonal antibody was used to perform western blot and immunocytochemistry in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:31
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Calbiochem anti-Bim antibody was used to perform immunoprecipitation in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:24
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 2012 to the paper
Millipore anti-human nestin antibody was used to perform immunohistochemistry in order to study NKCC1 modulation of glioma cell migration. more
total:17
Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. 2008 to the paper
Novus Biologicals anti-p75NTR antibody was used to perform immunocytochemistry in order to show that cellular phenotype can be changed after exposure to acid and bile salt in Barrett's epithelial cell line. more
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-WEE1 antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:3
RhoE Is required for keratinocyte differentiation and stratification. 2009 to the paper
Millipore mouse monoclonal anti-RhoE antibody (4) was used in western blot to study the role for RhoE in keratinocyte differentiation and stratification more
total:1
Identification and subclassification of new Atoh1 derived cell populations during mouse spinal cord development. 2009 to the paper
M. Goulding rabbit anti-FOXD3 antibody was used to incubate the embryos slides in order to reveal the existence of Atoh1 dependent cell types in the spinal cord.
total:1
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-Nodal antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization.
total:1
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. 2005 to the paper
Santa Cruz anti-TTK antibody (sc-540) was used in human cells and in immunoprecipitation, western blot to study the role for the effect of TTK/hMps1 on CHK2 in the regulation of DNA damage checkpoint.
total:9
Identification of a filamin docking site on PTP-PEST. 2006 to the paper
Chemicon International monoclonal antibody against filamin-A was used in immunocytochemistry to detect filamin-A expression in HeLa cells more
total:13
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB4 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:1
Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray. 2005 to the paper
LICR antibody against MAGE-A3 (M3H67) was used in immunohistochemistry to investigate the distribution of MAGE-A3 among different types and grades of human endometrial carcinomas.
- platelet activating factor receptor antibody
- platelet activating factor receptor gene knockdown
- platelet activating factor receptor cDNA
- platelet activating factor receptor protein
- platelet activating factor receptor inhibitor/activator/substrate/reporter
- platelet activating factor receptor ELISA/assay
- platelet activating factor receptor other
total:1
Relative levels of semen platelet activating factor-receptor (PAFr) and ubiquitin in yearling bulls with high content of semen white blood cells: implications for breeding soundness evaluation. 2007 to the paper
Cayman Chemicals PAF receptor antibody was used in western blot and immunohistochemistry to study the role of PAF receptor in fertility.
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:4
Combinatorial synergy induced by adenoviral-mediated mda-7 and Herceptin in Her-2+ breast cancer cells. 2006 to the paper
S Chada (Introgen Therapeutics) MDA-7 antibody was used in western blot to demonstrate that combination of Ad-mda7 with Herceptin may be a novel therapy for breast cancer. more
total:6
Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma. 2009 to the paper
Dako anti-MUM-1/IRF4 antibody (clone:MUM1P) was used in immunohistochemistry to analyze the expression pattern of MUM1, bcl-6, and CD138 along with the association of EBV in 222 well-characterized cases of BL. more
total:34
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Santa Cruz Biotechnology anti-Mcl-1 antibody was used to perform western blot in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:4
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability. 2009 to the paper
Chemicon International ADAM-15 was used to recognize the C-terminus amino acid sequence RPAPPPPAASSLYL in order to study the mechanism of activin receptor signaling regulating prostatic epithelial cell adhesion and viability more
total:4
Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-MelCAM antibody and mouse monoclonal anti-MelCAM antibody were used in human MCF-7 cells and paraffin sections from human tumor, and which were used in western blot and immunohistochemistry, to study the role for the effect of hypoxia on cross-talk between Syk and Lck in breast cancer progression and angiogenesis. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:3
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Abcam anti-ING4 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:10
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
IBL rabbit anti-ETB was used in 1:400 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR1 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:3
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. 2007 to the paper
Santa Cruz Biotechnology anti-EPAC antibody was used in western blot to determine whether the PDE4 sequestered by DISC1 is released after cAMP elevation. more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:17
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 to the paper
Zymed anti-Skp2 was used in 1:1000 dilution to perform western blot in order to show that CSN plays an important role for cell autophagy in K562 cells. more
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more
total:4
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. 2007 to the paper
Oncogene Research Products NOXA antibody was used in western blot to identify p18 (Hamlet) as a new cell-fate regulator. more
total:20
Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. 2009 to the paper
DakoCytomation S100 antibody was used in immunohistochemistry in order to demonstrate that the brain tuberous sclerosis complex (TSC) can be caused by the loss of function of Tsc2 in radial glia. more
total:1
Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma. 2009 to the paper
Abcam anti-Gli2 antibody was used to perform immunohistochemistry in order to study the roles of Atoh1 in sonic hedgehog signaling during the development of cerebellum.
total:15
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Affinity BioReagents anti-VDR (MA1-7101, 1:400) monoclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder. more
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
total:60
Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature. 2009 to the paper
Epitomics anti-calveolin-1 antibody was used for immunohistochemistry in order to show that a novel translocation involving chromosome 19 causes Xp11.2 translocation renal cell carcinoma. more
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more