mRNA Splicing - Minor Pathway
gene
reagent
sample publication
sample review
EFTUD2
elongation factor Tu GTP binding domain containing 2
GTF2F1
general transcription factor IIF subunit 1
total:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIF antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
GTF2F2
general transcription factor IIF subunit 2
LSM2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
NCBP1
nuclear cap binding protein subunit 1
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
NCBP2
nuclear cap binding protein subunit 2
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
POLR2B
RNA polymerase II subunit B
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
PRPF8
pre-mRNA processing factor 8
total:1
Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. 2007 to the paper
Santa Cruz Biotechnology anti-Prp8 was used in immunoprecipitation to isolate Prp8 and in western blot to detect Prp8 in HeLa cells
RNA polymerase II
RNA polymerase II subunit A
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
SC35
serine and arginine rich splicing factor 2
total:17
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Sigma mouse anti-SC35 antibody (1:5000) was used to perform immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
SF3B2
splicing factor 3b subunit 2
total:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 to the paper
Proteintech Group rabbit polyclonal anti-SF3b 145 was used to carry out western blot analysis in order to investigate the mechanism for CUGBP2 activating cardiac troponin T exon 5 inclusion
SF3B4
splicing factor 3b subunit 4
total:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 to the paper
Proteintech Group rabbit polyclonal anti-SF3b49 was used to carry out western blot analysis in order to investigate the mechanism for CUGBP2 activating cardiac troponin T exon 5 inclusion
SNRNP200
small nuclear ribonucleoprotein U5 subunit 200
SNRNP40
small nuclear ribonucleoprotein U5 subunit 40
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
total:4
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-SmB/B' antibody (sc-271094) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
SNRPD2
small nuclear ribonucleoprotein D2 polypeptide
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide
SNRPE
small nuclear ribonucleoprotein polypeptide E
total:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Santa Cruz Biotechnology mouse monoclonal B-Raf antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines more
SNRPF
small nuclear ribonucleoprotein polypeptide F
SNRPG
small nuclear ribonucleoprotein polypeptide G
SRSF1
serine and arginine rich splicing factor 1
total:4
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Zymed mouse anti-SF2/ASF antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
SRSF7
serine and arginine rich splicing factor 7
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
BD Bioscience mouse anti-9G8 antibody was used to perform immunoprecipitation in order to study the elongation of RNA Polymerase II during co-transcriptional splicing.