mRNA Splicing - Major Pathway
gene
reagent
sample publication
sample review
total:2
THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo. 2010 to the paper
Santa Cruz monoclonal antibodies against Aly/THOC4 were used in western blot to investigate the role of THOC5/Fms in the maintenance of hematopoiesis and the regulation of THOC1. more
total:3
Combinatorial control of signal-induced exon repression by hnRNP L and PSF. 2007 to the paper
BioLegend anti-hnRNPD polyclonal antibody was used in western blot in order to investigate the mechanisms of hnRNP L and PSF combinatorial control over the exon repression through signal-induced alternative splicing. more
total:1
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 to the paper
Bethyl Laboratories rabbit anti-CCAR1 antibody (1:10,000) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to prove that the association of AKAP350A and CCAR1 with RNA stress granules is microtubule dependent.
total:1
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. 2005 to the paper
Christine Milcarek (University of Pittsburgh) anti-CstF-77 antibody was used in western blot to demonstrate that CstF-64 influence gene expression and induce alternative poly (A) site selection..
total:6
A yeast model of FUS/TLS-dependent cytotoxicity. 2011 to the paper
Abcam anti-FUS antibody (1:1000) was used to perform western blot in order to study the FUS/TLS-dependent cytotoxicity in yeast. more
total:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIF antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
total:10
NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. 2013 to the paper
Abcam anti-hnRNP-C1/C2 antibody was used to perform western blot to investigate the role of nonsense mediated decay exons in the control of synaptic protein levels after seizure. more
total:6
Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. 2008 to the paper
Sigma monoclonal anti-hnRNP-A1 antibody was used to perform immunoprecipitation in order to study the relevant role of RNA binding proteins(RBPs) in posttranscriptional regulation of CML development and progression. more
total:3
The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA. 2013 to the paper
Santa Cruz anti-hnRNP A2/B1 antibody was used to perform western blot and immunoprecipitation in order to investigate the regulatory effect of HILDA complex on VEGF-A expression. more
total:2
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 to the paper
Abcam anti-hnRNP H antibody was used to perform western blot in order to study the interaction between TDP-43 and proteins that regulate RNA metabolism. more
total:6
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 to the paper
Epitomics anti-hnRNP K antibody was used to perform western blot in order to find out the PITX2 interacting and regulating networks. more
total:4
The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA. 2013 to the paper
Novus mouse monoclonal anti-hnRNP L antibody was used to perform immunoprecipitation in order to investigate the regulatory effect of HILDA complex on VEGF-A expression. more
total:2
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 to the paper
Bethyl Laboratories anti-hnRNP U antibody was used to perform western blot in order to study the interaction between TDP-43 and proteins that regulate RNA metabolism. more
total:1
Influenza virus targets the mRNA export machinery and the nuclear pore complex. 2007 to the paper
Proteintech Group anti-E1B-AP5 antibody was used in western blot in order to study the mechanisms used by influenza A virus to disrupt the mRNA nuclear export machinery.
total:3
The exon junction complex component Magoh controls brain size by regulating neural stem cell division. 2010 to the paper
Proteintech anti-Magoh antibody was used to perform immunohistochemical assays in order to study the genetic mechanisms of Magoh in controlling brain size. more
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
total:1
Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. 2007 to the paper
Santa Cruz Biotechnology anti-Prp8 was used in immunoprecipitation to isolate Prp8 and in western blot to detect Prp8 in HeLa cells
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Sigma Y14 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
total:17
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Sigma mouse anti-SC35 antibody (1:5000) was used to perform immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
total:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 to the paper
Proteintech Group rabbit polyclonal anti-SF3b 145 was used to carry out western blot analysis in order to investigate the mechanism for CUGBP2 activating cardiac troponin T exon 5 inclusion
total:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 to the paper
Proteintech Group rabbit polyclonal anti-SF3b49 was used to carry out western blot analysis in order to investigate the mechanism for CUGBP2 activating cardiac troponin T exon 5 inclusion
total:14
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-SMC1 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Abcam rabbit anti-U1A antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.
total:4
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-SmB/B' antibody (sc-271094) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Santa Cruz Biotechnology mouse monoclonal B-Raf antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines more
total:4
SRp20 and CUG-BP1 modulate insulin receptor exon 11 alternative splicing. 2009 to the paper
Zymed Laboratory mouse monoclonal anti-SRp20 antibody was used in western blot to study the roles for SRp20 and CUG-BP1 in modulating insulin receptor exon 11 alternative splicing. more
total:1
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal anti-SRm160 antibody K15 was used in western blot to study the association of SRm160-containing complexes with cohesin.
total:4
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Zymed mouse anti-SF2/ASF antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
total:4
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology HRS rabbit polyclonal antibody (M-79) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
BD Bioscience mouse anti-9G8 antibody was used to perform immunoprecipitation in order to study the elongation of RNA Polymerase II during co-transcriptional splicing.
total:2
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Abcam rabbit anti-U2AF65 antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
total:6
Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. 2013 to the paper
Abcam anti-YB-1 antibody was used to perform western blotting in order to determine the subcellular distribution of the hnRNP-Q. more