lysosomes
gene
reagent
sample publication
sample review
total:2
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-NPC1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:5
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-Rab7 antibody was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
total:13
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Santa Cruz Biotechnology primary anti-cathepsin D (H-75) was used to detect endogenous lysosomal and ER proteins by immunohistochemistry method in order to study the preferentially expressed characterization of the arylsulfatase I (ARSI) gene. more
total:24
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Abcam rabbit anti-LAMP2 was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
total:2
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Cell Signaling anti-RagC was used to perform western blot and immunocytochemistry in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation. more
total:1
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Sigma Prestige anti-RagB antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins.
total:2
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GLA polyclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease. more
total:3
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. 2005 to the paper
BD Biosciences anti-sortilin antibody was used in western blot and immunocytochemistry to study the role of sortilin in brain-derived neurotrophic factor secretory pathway more
total:14
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Chemicon rabbit polyclonal anti-Cathepsin B Ab (1:200) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
total:47
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
BD Biosciences anti-Lamp-1 antibody was used to perform western blot in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
total:3
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Upstate anti-Nedd4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown. more
total:1
Functional dissection of human and mouse POT1 proteins. 2009 to the paper
Sigma rabbit anti-humanTPP1 (1151) antibody was used in western blot in order to investigate the function of single-stranded telomeric DNA associated protein-POT1 in human and mice.
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-mu 3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 to the paper
Bethyl Laboratory Inc. rabbit anti-SKD1 antibody was used in western blot to study the interaction of the mammalian endosomal sorting complex required for rransport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1
total:19
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
BD anti-Rab5 antibody was used in immunocytochemistry in order to investigate the mechanism of the autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
total:70
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-CD71-APC antibody was used to perform flow cytometry in order to study the different trafficking mechanisms of endosomal Toll-like receptors mediated by UNC93B1. more
total:7
The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005 to the paper
BD Transduction Laboratories mouse monoclonal antibody against syntaxin 6 was used in immunocytochemistry to study the function of a DnaJ domain-containing protein RME-8 in endosomal trafficking. more
total:3
Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation. 2009 to the paper
BD Biosciences Itch monoclonal antibody was used to perform western blot and immunoprecipitation in order to demonstrate the key mechanisms that regulate p63 protein stability in vivo. more
total:14
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Santa Cruz anti-p62 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
total:10
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Cell Signaling Technology rabbit anti-LC3B antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:7
Vaccinia virus p37 interacts with host proteins associated with LE-derived transport vesicle biogenesis.. 2009 to the paper
Affinity BioReagents CI-MPR was used as primary antibody in immunofluorecent staining in order to study the interaction between the vaccinia virus p37 and host proteins associated with LE-derived transport vesicle biogenesis. more