lymphatic metastasis
gene
reagent
sample publication
sample review
total:10
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics anti-VEGF antibody (1:1000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:3
Correlation of vascular endothelial growth factor-D expression and VEGFR-3-positive vessel density with lymph node metastasis in gastric carcinoma. 2008 to the paper
R&D Systems goat polyclonal anti-VEGF-D antibody was used in immunohistochemistry to study the clinical value of VEGF-D expression and VEGFR-3 positive vessel density in gastric carcinoma with regard to lymphangiogenesis in paraffin sections from human tumor. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:9
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
R&D Systems anti-CCR7 monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:4
Altered regulation of Prox1-gene-expression in liver tumors. 2008 to the paper
Reliatech rabbit polyclonal anti-Podoplanin (1:500) antibody was used in immunohistochemistry to study Prox1-gene-expression in liver tumors more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:15
Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia. 2008 to the paper
Santa Cruz anti-VEGFR-3 (sc-321) antibody was used to perform immunohistochemistry in order to study the expression of VEGF-C and VEGFR-3 in the acute myeloid leukaemia patients' bone marrow. more
total:8
Reactivity with TdT in Merkel cell carcinoma: a potential diagnostic pitfall. 2008 to the paper
Dako anti-Cytokeratin 20(Ks20.8) antibody was used to perform immunohistochemistry in order to study the spectrum of immunoreactivity with TdT in MCC. more
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:7
Altered regulation of Prox1-gene-expression in liver tumors. 2008 to the paper
Reliatech rabbit polyclonal anti-Lyve-1 (1:500) antibody was used in immunohistochemistry to study Prox1-gene-expression in liver tumors more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:27
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 2012 to the paper
Cell Signaling anti-Ezrin antibody was used to perform immunoprecipitation in order to study NKCC1 modulation of glioma cell migration. more
total:8
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Abcam rabbit anti-nm23 antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells. more
total:12
Tumorigenic and metastatic activity of human thyroid cancer stem cells. 2010 to the paper
Dako anti-cytokeratin 19 antibody was used to perform immunohistochemistry in order to find out what activities of human thyroid cancer stem cells could be potential targets to treat thyroid carcinoma. more
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:123
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-Cyclin D1 antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:3
A novel germline PALB2 deletion in Polish breast and ovarian cancer patients. 2010 to the paper
DAKO anti-CK17 antibody was used for immunohistochemistry in order to show that PALB2 mutation can increase the possibility of familial breast cancer. more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
total:1
Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. 2006 to the paper
Abnova BRMS1 antibody was used in western blot and immunoprecipitation to study the role of BRMS1 in the metastasis of breast cancer.
total:1
MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization. 2009 to the paper
MBL International Corp. mouse anti-human RECK antibody was used in flow cytometry in order to study the role of MT1-MMP and RECK for the motility, adhesion, and mobilization of human hematopoietic progenitor cells.
total:6
Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry. 2008 to the paper
Santa Cruz Biotechnology anti-stratifin antibody was used in immunohistochemistry and western blot to discover head-and-neck cancer biomarkers. more
total:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 to the paper
Santa Cruz Biotechnology Tiam1 antibody (C-16) was used to perform co-immunoprecipitation analyse and chromatin immunoprecipitation assays in order to demonstrate the mechanism between Rac1 and the canonical Wnt signalling pathway in colorectal cancer cells. more
total:4
Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. 2008 to the paper
BD Transduction Laboratories mouse rabbit anti-Rch-1 antibody was used in immunocytochemistry in order to define a novel mechanism of synapse-to-nucleus communication via a synaptic Ca2+-sensor protein more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:11
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
BD Biosciences anti-EpCam antibody was used to perform purification of primary lung tumor cells in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:3
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
Santa Cruz Biotechnology anti-Twist monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
total:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 to the paper
Abcam rabbit polyclonal anti-GLUT1 antibody was used to perform immunoblot in order to study the roles of the glucose deprivation during the development of KRAS pathway mutation. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:4
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling. 2007 to the paper
Lab Vision S100A4 antibody was used in western blot to report an increase in S100A6 protein level in colon and lung cancer cells postexposure to ionizing radiation. more
total:9
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. 2010 to the paper
Santa Cruz Biotechnology anti-MMP7 antibody was used in immunohistochemistry to investigate the function of UPK1A in esophageal squamous cell carcinoma. more
total:4
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
Santa Cruz Biotechnology anti-Snail1 was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 to the paper
Serotec rat anti-EMMPRIN monoclonal antibody (1:200) was used in immunohistochemistry in order to examine potential association between EMMPRIN and MMP-9 expre more
total:38
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Santa Cruz PR monoclonal antibody was used in immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:8
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-Beclin 1 antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:10
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma. 2009 to the paper
Chemicon anti-CD24 antibody was used to perform immunohistochemistry in order to find out the potential therapeutic targets of the human head and neck squamous cell carcinoma. more
total:1
The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. 2005 to the paper
Dako polyclonal S100A2 (anti-S100A2) antibody was used in immunohistochemistry, immunocytochemistry, western blot, and immunoprecipitation to study the interaction between calcium-binding protein S100A2 and p53
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
total:7
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. 2010 to the paper
Invitrogen anti-ANXA1 andibody was used to perform immnunohistochemistry, western blot and ELISA in order to study the functions of Annexin A1 in the anti-inflammatory and neuroprotective role of microglia. more
total:5
Increased expression of stathmin in eutopic endometrium of patients with endometriosis. 2010 to the paper
Abcam polyclonal rabbit anti-human stathmin antibody was used to perform western blot and immunohistochemistry in order to study the overexpression of stathmin protein in eutopic endometrium of patients with endometriosis. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:11
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Santa Cruz Biotechnology anti-human SPARC antibody was used for western blot and immunohistochemistry in order to study the role of SPARC in therapeutic process for ovarian cancer. more
total:7
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 to the paper
Oncogene Research Products Topoisomerase II antibody was used to perform immunoblotting in order to demonstrate the mechanism between Rac1 and the canonical Wnt signalling pathway in colorectal cancer cells. more
total:76
Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-vimentin (C-20 and H-84, 1:1000) antibody was used to perform western blot in order to study the formation mechanism of tubulin-based microtentacles in detached breast tumor cells. more
total:1
Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism. 2010 to the paper
BD Transduction Laboratories anti-PINCH antibody was used for western blot in order to investigate the role of ILK in the regulation of human intestinal cells migration and proliferation.
total:2
Aquaporin-3 expression in human fetal airway epithelial progenitor cells. 2005 to the paper
Alomone rabbit polyclonal anti-aquaporin channel 3 (antiAQP3) antibody was used in immunohistochemistry and flow cytometry to study the progenitor potentialities of human fetal basal and suprabasal airway epithelial cells. more
total:2
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 to the paper
Santa Cruz anti-E-FABP antibody was used to perform western blot in order to study the proteomic of the keratinocytes after the treatment of low dose arsenic and ionizing radiation exposure. more
total:1
Uteroglobin suppresses SCCA gene expression associated with allergic asthma. 2005 to the paper
Santa Cruz Biotechnology mouse monoclonal antibody for human SCCA-2 was used in western blot to detect human SCCA-2 expression in human HBEC cells.
total:1
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Abcam anti-USP22 antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation.
total:19
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Becton Dickinson anti-Thy1 was used in 40 ul/mL to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:39
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Sigma Aldrich anti-fibronectin antibody was used to perform immunocytochemistry and western blot in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:3
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Abcam anti-ING4 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:3
Melanoma Inhibitory Activity (MIA) increases the invasiveness of pancreatic cancer cells. 2005 to the paper
Roche Diagnostic GmbH anti-MIA antibody (which was in ELISA kit) was used in human cells and in ELISA to study the effect of melanoma inhibitory activity (MIA) on the invasiveness of pancreatic cancer cells. more
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Chemicon MMP-11 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:4
ZEB-1, a repressor of the semaphorin 3F tumor suppressor gene in lung cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-ZEB-1 antibody was used for western blot in order to suggest that ZEB-1 can inhibit semaphorin 3F tumor suppressor gene in lung cancer cells. more
total:2
Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. 2006 to the paper
Santa Cruz Biotechnology Gli-1 antibody was used in immunocytochemistry to determine whether the synthetic microRNAs (miRNA) could effectively target tumor cells. more
total:2
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Epitomics anti-Aldh1 antibody (1:150) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:13
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Santa Cruz Biotechnology anti-EphA2 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
total:10
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-HMGB1 antibody was used to perform western blot in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:112
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-ERa antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:1
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Chemicon International anti-IDO monoclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma.
total:1
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 to the paper
Active Motif rabbit polyclonal anti-RUNX3 antibody was used in immunocytochemistry to study the interaction between E4orf6, E1B-55K, and RUNX1 and the association of the RUNX1 with centers of viral DNA and RNA synthesis.