liver neoplasms
gene
reagent
sample publication
sample review
total:6
Expression and location of alpha-fetoprotein during rat colon development. 2009 to the paper
Santa Cruz Biotechnology goat polyclonal anti-AFP antibody was used to carry out western blot analysis in order to invesitgate the expression and location of AFP protein in rat developmental colon. more
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:3
Hippo pathway effector Yap is an ovarian cancer oncogene. 2010 to the paper
Santa Cruz Biotechnology anti-Yap antibody was used in western blot and immunohistochemistry to study the effect of the hippo pathway effector Yap on the progression of ovarian cancer. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:3
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-SHP antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more
total:1
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. 2009 to the paper
BD Biosciences mouse monoclonal anti-TFCP2 antibody was used to carry out immunofluorescence assays in order to investigate the role for AEG1 in regulating Hepatocellular carcinoma pathogenesis.
total:1
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. 2010 to the paper
Abcam mouse anti-CHD1L antibody (1:50) was used in immunohistochemistry in order to study the CHD1L-ARHGEF9-Cdc42-EMT pathway involved in hepatocellular carcinoma (HCC) progression and metastasis.
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:17
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Epitomics anti-Notch1 antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:2
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-arginase 1 antibody was used in western blot and immunohistochemistry to study the role for elevated arginase expression in HCV associated HCC more
total:1
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. 2007 to the paper
Santa Cruz cyclin G1 antibody was used in western blot to identify p18 (Hamlet) as a new cell-fate regulator.
total:1
The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells. 2006 to the paper
Santa Cruz ZBP-89 antibody (1:200) was used in western blot to demonstrate taht ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells.
total:5
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
For exploring the effect of DLC1 on angiogenesis, BD Biosciences anti-DLC1 monoclonal antibody was used for performing immunohistochemistry. more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:47
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Abcam GRP78/BiP rabbit polyclonal (1:25) was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:1
Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells. 2005 to the paper
Cell Signaling anti-XIP antibody was used in western blot to study the role of CCN in ovarian carcinomas.
total:2
Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding. 2007 to the paper
Santa Cruz polyclonal FUT6 antibody against C-terminus was used in western blot and immunocytochemistry to study the interaction of glycodelin-A with fucosyltransferase on human sperm plasma membrane and the inhibition of spermatozoa-zona pellucida binding more
total:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 to the paper
Serotec rat anti-EMMPRIN monoclonal antibody (1:200) was used in immunohistochemistry in order to examine potential association between EMMPRIN and MMP-9 expre more
total:11
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
BD Biosciences anti-EpCam antibody was used to perform purification of primary lung tumor cells in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:11
Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours. 2008 to the paper
Santa Cruz Biotechnology anti-Jab-1 antibody was used to perform immunohistochemistry in order to study the role of cells cycle regulators in gastrointestinal stromal tumours. more
total:4
Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 to the paper
Santa Cruz anti-RASSF1A was used to perform western blot in order to show that aneuploidy in tumor cells is associated with STAG2 inactivation. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:1
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells. 2005 to the paper
Chemicon International anti-endothelial cell antibody P1H12 was used in human umbilical vein endothelial cells (HUVEC) and in flow cytometry to study the role for HEV-restricted sulfotransferase in rheumatoid arthritis and the interaction of it with lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:12
Tumorigenic and metastatic activity of human thyroid cancer stem cells. 2010 to the paper
Dako anti-cytokeratin 19 antibody was used to perform immunohistochemistry in order to find out what activities of human thyroid cancer stem cells could be potential targets to treat thyroid carcinoma. more
total:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 to the paper
Zymed rabbit anti-Cks1 (C-term) antibody was used in western blot to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:3
Opposing effects of interferon-alpha and interferon-gamma on the expression of major histocompatibility complex class I chain-related A in tumors. 2008 to the paper
R&D Systems anti-MICA antibody was used to perform flow cytometry in order to study the differential effects of IFN-alpha and IFN-gamma on tumor cells. more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:3
Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. 2008 to the paper
Santa Cruz Biotechnology Inc Klf6 rabbit polyclonal antibodies were used to probe nitrocellulose blots in order to study differential regulation of Kr ppel-like factor family transcription factor expression in neonatal rat cardiac myocytes. more
total:1
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. 2007 to the paper
Abgent Monoclonal anti-His antibody was used to perform immunoprecipitation in order to investigate the role of human Tim-Tipin complex during the UV-induced intra-S checkpoint.
total:100
Plasma membrane contributes to the formation of pre-autophagosomal structures. 2010 to the paper
Abcam anti-AP1-A1 antibody was used to perform western blot in order to study the role of plasma membrane in the formation of preautophagosomal structures. more
total:6
CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis. 2008 to the paper
Alexis anti-ARNT antibody was used to perform western blot in order to study the roles of the CUL2 in the activity of hypoxia-inducible factor and vasculogenesis. more
total:5
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Millipore mouse monoclonal anti-MPM-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres. more
total:1
The FUSE binding protein is a cellular factor required for efficient replication of hepatitis C virus. 2008 to the paper
Santa Cruz Biotechnology anti-FBP antibody was used in western blot in order to demonstrate that FUSE Binding Protein is a cellular factor required for efficient replication of Hepatitis C Virus
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:3
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-Pim-2 monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more