kidney neoplasms
gene
reagent
sample publication
sample review
total:14
The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA. 2013 to the paper
GeneTex anti-VHL antibody was used to perform western blot and immunoprecipitation in order to investigate the regulatory effect of HILDA complex on VEGF-A expression. more
total:1
Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature. 2009 to the paper
Santa Cruz Biotechnology anti-TFE3 antibody was used for immunohistochemistry in order to show that a novel translocation involving chromosome 19 causes Xp11.2 translocation renal cell carcinoma.
total:2
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-BAF180 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel monoclonal anti-FH antibody was used in ELISA to study the association of the extracellular matrix and inflammation
total:4
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. 2007 to the paper
Santa Cruz anti-CAIX antibody was used to perform western blot in order to study the dependency on oxidative phosphorylation during transformation of human mesenchymal stem cells. more
total:8
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Abcam polyclonal PAX 2 antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
total:9
Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha. 2010 to the paper
Novus Biologicals HIF2alpha antibody was used for ChIP assays in order to study HIF-binding and Ets-binding motifs on the PTPRZ1 promoter and show that PTPRZ1 can be activated by HIF-2. more
total:1
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Abcam polyclonal PAX 8 antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer.
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:17
The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/Omi. 2010 to the paper
NeoMarkers anti-WT1 antibody was used to carry out western blot analysis in order to investigate the regulation of apoptosis and the oncogenic activities of WT1 by HtrA2. more
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:1
Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys. 2007 to the paper
Novus Biologicals rabbit polyclonal PHD1 antibody was used in immunohistochemistry to demonstrate the expressions of three isoforms of PHD and their distributions in different kidney regions.
total:1
Cell-cell contact globally activates microRNA biogenesis. 2009 to the paper
Abcam anti-TRBP antibody was used to perform western blot in order to study the association between the cell-cell contact and microRNA biogenesis.
total:8
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB1 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:1
Nicotinamide N-methyltransferase upregulation inversely correlates with lymph node metastasis in oral squamous cell carcinoma. 2007 to the paper
Richard Weinshilboum rabbit polyclonal NNMT antibody was used in western blot at 1:1000 dilution and immunohistochemistry at 1:500 dilution to study the relationship between tumor characteristics and NNMT levels in OSCC.
total:2
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. 2008 to the paper
Chemicon polyclonal rabbit anti-BLBP antibody (AB9558) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis. more
total:26
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 to the paper
Epitomics anti-TSC2 antibody was used to perform western blot and immunoprecipitation in order to study the mechanism by which carboxy terminal tail of polycystin-1 repress mTOR signaling via membrane retention of TSC2. more
total:2
Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. 2007 to the paper
Rockland rabbit anti-SFRP1 polyclonal antibody (600-401-475) antibody was used in western blot (1:100) and in immunohistochemistry (1:300) to study the role of SFRP1 down-regulation in human hepatocellular carcinoma more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:3
Loss of FGF-dependent mesoderm identity and rise of endogenous retinoid signalling determine cessation of body axis elongation. 2012 to the paper
Santa Cruz rabbit anti-Brachyury antibody was used to perform immunocytochemistry in order to study the mechanism that underlied termination of body axis elongation in embryos. more
total:27
Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon. 2009 to the paper
Dako Cytomation anti-pan-Cytokeratin antibody was used in immunohistochemistry to define the importance and role of cortactin in HNSCC tumor progression more
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 to the paper
Santa Cruz anti-Flk-1 antibody was used to perform immunoprecipitation in order to reveal the critical role of prorenin receptor and vacuolar H+-ATPase-mediated acidification in Wnt signaling. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:2
Mutational analysis reveals distinct features of the Nox4-p22 phox complex. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-Nox4 (7843) polyclonal antibody was used to perform western blot and immunocytochemistry in order to study the interaction of the key regulatory p22phox subunit with Nox4. more
total:125
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Millipore anti-mouse CD31 antibody was used to perform immunohistochemistry in order to study the inhibition of antifungal drug thiabendazole to tumor growth in a mouse xenograft model. more
total:2
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 to the paper
Affinity BioReagents anti-thyroid hormone receptor anti-sera was used in immunoprecipitation in order to investigate the cooperation between thyroid hormone receptor beta2 and p160 coactivator PAS-B through multiple contact surfaces. more
total:3
Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites. 2008 to the paper
Santa Cruz Biotechnology anti-Ndrg2 goat polyclonal antibody was used in western blot in order to study the role of N-Myc downstream-regulated gene 2 in carcinogenesis of the thyroid more
total:1
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. 2006 to the paper
Clonegene Dicer antibody was used in immunohistochemistry to detect Dicer expression in benign human prostate epithelium and neoplastic prostate tissue, in western blot to examine Dicer expression in RWPE-1 and DU145 human prostate cancer cell lines, and in immunocytochemistry to detect Dicer expression in DU145 cell line.
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:3
Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. 2008 to the paper
Brigham and Women's Hospital and Harvard Medical School mouse monoclonal antibody against Kim-1 was used in immunohistochemistry to compare kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney. more
total:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 to the paper
Santa Cruz Biotechnology anti-HNF1B antibody was used for western blot in order to investigate the role of HNF-1beta in the regulation of PKD Modifier Gene Kif12. more
total:4
Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 to the paper
Santa Cruz anti-RASSF1A was used to perform western blot in order to show that aneuploidy in tumor cells is associated with STAG2 inactivation. more
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
total:2
Expression of components of the renin-angiotensin system in autosomal recessive polycystic kidney disease. 2005 to the paper
Dr. Tadashi Inagami renin antibody was used in immunohistochemistry to study the expression of components of the renin-angiotensin system in autosomal recessive polycystic kidney disease. more
total:22
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD10 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:19
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-Ku70 antibody was used to perform immunoblotting in order to studythe role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:84
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Santa Cruz Biotechnology anti-STAT1 polyclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma. more
total:18
Valproic acid resensitizes cisplatin-resistant ovarian cancer cells. 2008 to the paper
Transduction Laboratories anti-hMSH2 antibody was used in immunocytochemistry to show the effect of VPA and cisplatin on ovarian cancer cells. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:3
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-SDH antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA. more
total:11
A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. 2008 to the paper
R&D Systems monoclonal anti-CXCR3 was used to perform blocking or activating experiments in order to show that a computational-based peptidomics can be used to identify peptides inhibiting the proliferation and migration of endothelial cells systematically. more
total:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:14
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-HuR antibody(3A2, 1:1000) was used to perform immunoblotting in order to characterize the TAR DNA-binding Protein-43's alternative isoforms inclusion body. more
total:7
Lysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomas. 2009 to the paper
Santa Cruz Biotechnology MYCN antibody was used to perform western blot in order to investigate the relations between LAPTM5 and spontaneous regression of neuroblastomas more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:7
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Chemicon UCH-L1 antibody was used in western blot at dilution of 1/2000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:7
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
R&D Systems anti-Epo antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:9
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
R&D Systems monoclonal anti-human HGF antibody (MoAb) was used in blocking or activating expriments to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-JNK1 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:4
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling. 2007 to the paper
Lab Vision S100A4 antibody was used in western blot to report an increase in S100A6 protein level in colon and lung cancer cells postexposure to ionizing radiation. more
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
total:129
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
AbCam anti-Ki67 was used to perform immunohistochemistry in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:4
Cannabinoid CB? receptor is downregulated in clear cell renal cell carcinoma. 2010 to the paper
ABR Affinity BioReagents anti-CB1 polyclonal antibody was used to perform western blot and immunohistochemistry in order to study the downregulation of cannabinoid receptor CB1 in clear cell renal carcinoma. more
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:1
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 to the paper
Active Motif rabbit polyclonal anti-RUNX3 antibody was used in immunocytochemistry to study the interaction between E4orf6, E1B-55K, and RUNX1 and the association of the RUNX1 with centers of viral DNA and RNA synthesis.
total:40
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Santa Cruz Biotechnology PE-conjugated anti-IGF-1R antibody was used in flow cytometry to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more