keratinocytes
gene
reagent
sample publication
sample review
p63
tumor protein p63
total:26
Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation. 2014 to the paper
Santa Cruz Biotechnology anti-p63 antibody was used to perform immunohistochemistry in order to study TNFa/TNFR2 axis protective role for skin against DUOX1-mediated oxidative stress. more
involucrin
total:13
Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice. 2010 to the paper
Babco anti-involucrin antibody was used for western blot in order to investigate the role of N-WASP in the regulation of Wnt signaling and hair follicle cycling in mice. more
dsg3
desmoglein 3
total:3
Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. 2008 to the paper
Zymed Laboratories anti-desmoglein 3 antibody was used to perform immunohistochemistry in order to study the distribution of cell membrane proteins and extracellular matrix proteins in human corneoscleral limbus rims. more
FLG
filaggrin
total:5
Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice. 2010 to the paper
Babco anti-filaggrin antibody was used for western blot in order to investigate the role of N-WASP in the regulation of Wnt signaling and hair follicle cycling in mice. more
Dsg1
desmoglein 1
total:5
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. 2006 to the paper
Research Diagnostics monoclonal anti-Dsg1 antibody (clone P124, which recognizes N-terminal extracellular domain of Dsg1) was used in parental A431 human vulvar epidermoid carcinoma cells and in western blot to study the function for Dsg1 in facilitating apoptotic elimination of damaged cells. more
cytokeratin 14
keratin 14
total:16
The intercellular adhesion molecule, cadherin-10, is a marker for human prostate luminal epithelial cells that is not expressed in prostate cancer. 2008 to the paper
Chemicon 1 mg/ml anti-human CK14 antibody was used in immunohistochemistry to stduy the relationship between the expression of differentiation markers and cadherin-10 expression in human prostate epithelium. more
AQP3
aquaporin 3 (Gill blood group)
total:2
Aquaporin-3 expression in human fetal airway epithelial progenitor cells. 2005 to the paper
Alomone rabbit polyclonal anti-aquaporin channel 3 (antiAQP3) antibody was used in immunohistochemistry and flow cytometry to study the progenitor potentialities of human fetal basal and suprabasal airway epithelial cells. more
KRT17
keratin 17
total:3
A novel germline PALB2 deletion in Polish breast and ovarian cancer patients. 2010 to the paper
DAKO anti-CK17 antibody was used for immunohistochemistry in order to show that PALB2 mutation can increase the possibility of familial breast cancer. more
NFX1
nuclear transcription factor, X-box binding 1
hBD-2
defensin beta 4A
total:11
Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis. 2010 to the paper
Biologo polyclonal rabbit anti-human HBD-2 was used to perform immunohistochemistry in dilution 1:100 and ELISA in dilution 1:1000 in order to show that the levels of human neutrophil peptides 1-3 secretion is inhibited by tumor necrosis factor and norepinephrine in mixed synovial tissue cultures from osteoarthritis and rheumatoid arthritis patients. more
KRT5
keratin 5
total:20
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Abcam anit-keratin 5 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
DEFB103B
defensin beta 103B
total:2
Nuclear hBD-1 accumulation in malignant salivary gland tumours. 2008 to the paper
Gentaur hBD-3 antibody was used in immunohistochemistry in order to characterize proteins involved in cell cycle control more
caspase 14
total:1
Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B. 2005 to the paper
BD Biosciences anti-caspase-14 antibody was used in human Jurkat cell free extract and in western blot and blocking expriments to study the hierarchy of granzyme B-initiated caspase activation events.
ABCA12
ATP binding cassette subfamily A member 12
LAMA3
laminin subunit alpha 3
total:3
Nephrotic syndrome and aberrant expression of laminin isoforms in glomerular basement membranes for an infant with Herlitz junctional epidermolysis bullosa. 2005 to the paper
Chemicon monoclonal anti-laminin alpha3 chain antibody P3H9 was used in immunohistochemistry to study the association of laminin isoforms with herlitz junctional epidermolysis bullosa in a case complicated by nephrotic syndrome. more
LL-37
cathelicidin antimicrobial peptide
total:8
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
HyCult Technologies anti-cathelicidin (3D11, 1:200) monoclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder. more
IL 22
interleukin 22
total:6
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems APC-labeled anti-IL-22mAb was used to perform flow cytometry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
IRF6
interferon regulatory factor 6
total:3
Human ?-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. 2012 to the paper
Difco anti-LPS was used to perform immunocytochemistry in order to show that mucosal innate immunity could be promoted by HD6 self-assembly. more
MMP-9
matrix metallopeptidase 9
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
KLK5
kallikrein related peptidase 5
total:1
Premature terminal differentiation and a reduction in specific proteases associated with loss of ABCA12 in Harlequin ichthyosis. 2009 to the paper
Santa Cruz anti-KLK5 antibody was used to perform immunohistochemistry in order to study the morphological and biochemical alterations associated with the loss of ABCA12 in harlequin ichthyosis.
S100A7
S100 calcium binding protein A7
total:5
Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry. 2008 to the paper
Santa Cruz Biotechnology anti-S100-A7 antibody was used in immunohistochemistry and western blot to discover head-and-neck cancer biomarkers. more
TNF-alpha
tumor necrosis factor
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
EGFR
epidermal growth factor receptor
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
KAZN
kazrin, periplakin interacting protein
OSMR
oncostatin M receptor
total:3
Breast cancer cells stimulate neutrophils to produce oncostatin M: potential implications for tumor progression. 2005 to the paper
R&D Systems anti-oncostatin M antibody was used in ELISA to study the role of oncostatin M producing by neutrophils stimulated by breast cancer cells. more
S100A9
S100 calcium binding protein A9
total:6
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 to the paper
Santa Cruz anti-S100A9 antibody was used to perform western blot in order to study the proteomic of the keratinocytes after the treatment of low dose arsenic and ionizing radiation exposure. more
CCL20
C-C motif chemokine ligand 20
total:1
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells. 2008 to the paper
R&D Systems CCL20 antibdoy (1:100) was used in immunohistochemistry in order to study roles of EBNA1 in the escape of EBV-infected HL cells from the virus-specific CTL response
HB-EGF
heparin binding EGF like growth factor
total:6
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
R&D Systems goat anti-HB-EGF polyclonal antibody was used in immunoprecipitation and immunohistochemistry (1:50) in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
ITGB4
integrin subunit beta 4
total:12
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-ITGB4 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
TLR2
toll like receptor 2
total:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 to the paper
Hycult Biotechnologies monoclonal anti-TLR2 was used to perform ELISA in order to show that Toll-like receptors in human and murine adipose tissue participate omental adipose tissue-related inflammation. more
S100A8
S100 calcium binding protein A8
total:5
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 to the paper
BMA Biomedicals monoclonal anti-myeloid related protein (MRP) 8 antibody (8-5c2) was used in immunohistochemistry to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. more
TGF-beta1
transforming growth factor beta 1
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
CKAP4
cytoskeleton associated protein 4
total:2
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 to the paper
Sigma anti-CLIMP63 (polyclonal) antibody was used to perform immunoblotting in order to study the effect of p180 on the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. more
IL1A
interleukin 1 alpha
total:5
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. 2006 to the paper
R & D Systems monoclonal anti-human IL-1alpha antibody was used in human SSc fibroblasts and in immunocytochemistry, immunoprecipitation to study the effect of intracellular IL-1alpha-binding proteins on biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. more
Notch1
notch receptor 1
total:17
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Epitomics anti-Notch1 antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
LAMC2
laminin subunit gamma 2
total:6
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Millipore anti-laminin gamma 2 chain antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
KLK7
kallikrein related peptidase 7
total:1
Premature terminal differentiation and a reduction in specific proteases associated with loss of ABCA12 in Harlequin ichthyosis. 2009 to the paper
Santa Cruz anti-KLK7 antibody was used to perform immunohistochemistry in order to study the morphological and biochemical alterations associated with the loss of ABCA12 in harlequin ichthyosis.