jurkat cells
gene
reagent
sample publication
sample review
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-SLP-76 (BLNK)(pY128) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:11
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology LAT antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:19
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Upstate ZAP-70 antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo. more
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-Btk/Itk (pY551/pY511) was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:2
The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association. 2008 to the paper
Prosci anti-CARD11 antibody was used in western blot in order to demonstrate that CARD11 can recruit signaling cofactors independently of one another in a signal-inducible manner. more
total:5
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Cell signaling rabbit anti-NFAT1 antibody was used to perform immunocytochemistry in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:17
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-2 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology FAS antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
total:4
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-NIK monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:11
Itk derived signals regulate the expression of Th-POK and controls the development of CD4 T cells. 2010 to the paper
BD Pharmingen anti-V alpha2 antibody was used in flow cytometery to to investigate the role of Itk regulation in CD4/CD8 commitment. more
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
total:6
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-Bcl10 monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:12
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. 2006 to the paper
Santa Cruz Biotechnology anti-Fas-L antibody was used in western blot to study the role of HYAL1-v1 in regulating in bladder cancer growth, infiltration, and angiogenesis in transfected human HT1376 bladder cancer cells. more
total:20
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
eBioscience anti-CD3 monoclonal antibody OKT3 was used to stimulate CD4+ T cell in order to study novel HIV-1 capture mechanism. more
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:6
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-TRAIL antibody was used in western blot to investigate the role of human BVR in sodium arsenite (As) mediated induction of HO-1 and in cytoprotection against apoptosis by small interference RNA-mediated gene silencing. more
total:75
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-caspase-9 antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
total:3
LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy. 2007 to the paper
Santa Cruz Biotechnology anti Cbl-b G-1 antibody was used in western blot and immunoprecipitation to identify LRIG1 as a novel negative regulator of the Met receptor and its role on opposing Met and Her2 synergy more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:2
Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP. 2011 to the paper
Abnova anti-SAP mAb was used to perform intracellular flow cytometric analysis in order to identify SAP expression in the lymphocytes obtained from XLP patients. more
total:2
Tal1/SCL binding to pericentromeric DNA represses transcription. 2005 to the paper
Geneka Biotechnology Tal1/SCL-specific antibody was used in immunoprecipitation to isolate DNA-Tal1-SCL complexes formed in vitro by incubating genomic DNA with human K562 nuclear extract, in CHIP assay to investigate the association between Tal1/SCL and EEGS in human K562 cells, and in western blot to detect Tal1/SCL in K562 more
total:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-RIP antibody was used in western blot to study the effect of repression of NF-kB and activation of AP-1 on apoptosis in prostate cancer cells. more
total:15
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys. 2008 to the paper
BD Biosciences anti-CD69 antibody was used to perform flow cytometric analysis in order to study the determinants of the level of viremia in naturally SIV-infected SMs. more
total:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Abcam Caspase-3 antibody was used to perform immunohistochemistry in order to study theeffect of thiabendazole on proliferation and apoptosis of human cells. more
total:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 to the paper
Sigma CnB1 antibody was used in western blot to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. more
total:6
Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1. 2008 to the paper
Sigma FLAG antibody (1:1000) was used to perform western blot in order to study the funtion of phosphorylation of gamma-binding domain of IkB kinase beta. more
total:10
Fas death receptor enhances endocytic membrane traffic converging into the Golgi region. 2009 to the paper
Santa Cruz Biotechnology CD43 was used in immunocytochemistry in order to study the mechanism of endocytic membrane traffic converging into the golgi region more
total:3
Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins. 2005 to the paper
Santa Cruz Biotechnology anti-CREM-1 antibody was used in western blot to study the role of cAMP-response element binding (CREB) and modulator (CREM and CREM 2) proteins in the expression of target genes of the cAMP pathway. more
total:19
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 to the paper
Cell Signaling Technology anti-FADD antibody was used to perform western blot in order to assess the effect of Rk1 on cell viability and telomerase activity. more
total:4
Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. 2007 to the paper
BD Biosciences NFATc1 antibody was used in immunohistochemistry to study the role of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:123
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Invitrogen biotin-labeled anti-CD45 mAb was used for cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:1
A novel activity for substance P: stimulation of peroxisome proliferator-activated receptor-gamma protein expression in human monocytes and macrophages. 2008 to the paper
Abcam rabbit polyclonal anti-NK1 receptor antibody (ab466) was used in western blot to evaluate the effects of SP on PPAR-gamma protein expression in monocytes and macrophages (MDMs: monocyte-derived macrophages) from healthy smokers and non-smokers.
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:15
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 to the paper
eBioscience rabbit polyclonal anti-DR5 antibody was used in flow cytometry in order to investigate the roles of Fas ligand and TRAIL in the regulation of murine thymic graft-versus-host disease. more
total:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 to the paper
Sigma-Aldrich anti-calcineurin A antibody was used in western blot in order to deduce that calcineurin activity and apoptosis of leukemic lymphocytes can be modulated by GC-mediated upregulation of RCAN1-1. more
total:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-JNK1 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz mouse anti-Tak1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
total:3
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 to the paper
Sigma rabbit polyclonal anti-RUNX1 antibody was used in immunocytochemistry to study the interaction between E4orf6, E1B-55K, and RUNX1 and the association of the RUNX1 with centers of viral DNA and RNA synthesis. more
total:23
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 to the paper
Santa Cruz Caspase-7 antibody was used in western blot in order to analyze changes in a subproteome of ~800 proteins in the promyelocytic leukemia cell line HL-60 upon treatment with the proteasome inhibitor PSI more
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:100
Plasma membrane contributes to the formation of pre-autophagosomal structures. 2010 to the paper
Abcam anti-AP1-A1 antibody was used to perform western blot in order to study the role of plasma membrane in the formation of preautophagosomal structures. more
total:12
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6. 2010 to the paper
Abcam monoclonal anti-caspase-6 antibody was used for western blot in order to investigate the role of DJ-1 mutations in the regulation of Parkinson disease pathology. more
total:27
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
Upstate Biotech anti-Bak NT antibody was used to perform immunoprecipitation and western blot in order to study the interactions between Bak and F1L or Mcl1. more
total:5
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKC-eta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:14
Altered gene expression in early atherosclerosis is blocked by low level apolipoprotein E. 2008 to the paper
eBioscience CD11a antibody was used in immunohistochemistry in order to study the linkage between changes of adhesion molecules/cofactors and atherosclerosis more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more
total:1
Regulation by P2X7: epithelial migration and stromal organization in the cornea. 2008 to the paper
Santa Cruz Biotechnology pannexin-1 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds
total:3
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpS3 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay. more
total:6
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 to the paper
Epitomics anti-hnRNP K antibody was used to perform western blot in order to find out the PITX2 interacting and regulating networks. more
total:35
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 to the paper
Santa Cruz anti-Bid was used to perform western blot in order to show that chemotherapy is efficient for patients with high mitochondrial priming more
total:1
Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. 2007 to the paper
Abgent anti-TRPM7 was used to perform immunohistochemistry in order to study TRPM7-like's roles in cell proliferation in human head and neck turmor cells.
total:5
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Santa Cruz anti-cyclin T1 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Millipore anti-IKK2 antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
total:8
Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals. 2008 to the paper
Santa Cruz USF (C20) antibody was used in ChIP assays in order to demonstrate that a specific gene loop conformation is imposed on integrated HIV-1 provirus after transcriptional activation more
total:175
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-PARP1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:34
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Santa Cruz Biotechnology anti-Mcl-1 antibody was used to perform western blot in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:11
Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours. 2008 to the paper
Santa Cruz Biotechnology anti-Jab-1 antibody was used to perform immunohistochemistry in order to study the role of cells cycle regulators in gastrointestinal stromal tumours. more
total:10
Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane. 2009 to the paper
NeoMarkers moesin antibody was used in western blot in order to study the role of phospholipase C in rapid cytoskeletal remodeling and the role of PIP2 in hydrolysis-mediated ERM inactivation. more