insulin resistance
gene
reagent
sample publication
sample review
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
total:37
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. 2011 to the paper
Invitrogen anti-phospho-IRS (Y612) was used to perform western blot in order to show that Grb10 was indentified as a negative regulator of insulin signaling by phosphoproteomic analysis. more
total:22
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti subunit of insulin receptors (IR) antibody was used in western blot and immunocytochemistry to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands. more
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
total:6
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Ob antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 to the paper
Upstate Biotechnology anti-TCF-4 antibody was used in immunoprecipitation and western blotting to investigate the action mechanism of the growth inhibition induced by bis[2-(acylamino)phenyl] disulfide. more
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
total:2
Juvenile dermatomyositis calcifications selectively displayed markers of bone formation. 2009 to the paper
R&D Systems anti-OC antibody was used to carry out immunohistochemistry assays in order to determine the presence of SIBLING protein and bone components in Juvenile Dermatomyositis pathologic calcifications. more
total:13
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Upstate Irs2 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
total:1
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. 2006 to the paper
Santa Cruz Biotechnology goat affinity-purified polyclonal anti-MT2 antibody (sc-28453) were used in human placental tissue and placental choriocarcinoma cell lines, and which were used in western blot and immunocytochemistry, to study the expression and role of melatonin receptors in human placenta choriocarcinoma cell lines.
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
R&D systems anti-fetuin A antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
total:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Abcam monoclonal anti-C-reactive protein (CRP) antibody was used in immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
total:1
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-AP antibody was used to perform immunofluorescence in order to study the involvement of apelin in fibrogenesis during human liver disease.
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:9
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 to the paper
Santa Cruz Biotechnology OB-R antibodies (C-20: specific for long form of leptin receptor, H-300: for both long and short form of leptin receptor, mouse monoclonal B-3: for both long and short forms of leptin receptor) were used in immunoprecipitation (C-20 and H-300) and western blot (B-3) to study the recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 by leptin and its stimulation of breast cancer cells. more
total:7
Constitutive overexpression of pigment epithelium-derived factor inhibition of ocular melanoma growth and metastasis. 2010 to the paper
Santa Cruz anti-PEDF antibody was used in western blot to investigate the role of lentivirus-mediated gene transfer of PEDF in the regulation of the growth of ocular melanoma and its hepatic micrometastasis. more