hiv infections
gene
reagent
sample publication
sample review
total:2
Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome. 2008 to the paper
Abgent rabbit polyclonal anti-C2orf37 antibody was used to perform immunohistochemistry in order to study the C2orf37 Mutations mediated Woodhouse-Sakati syndrome. more
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
total:2
BST-2 diminishes HIV-1 infectivity. 2010 to the paper
NIH AIDS Research and Reference Reagent Program antiserum anti-human BST-2 antibody was used to perform western blot in order to study the infectivity of HIV-1 reduced by BST-2. more
total:1
APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication. 2008 to the paper
Abnova mouse polyclonal anti-human A3F antibody was used in western blot to study the roles for the interaction between APOBEC3G and APOBEC3F with an endogenous cofactor in inhibition of HIV-1 replication.
total:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
PharMingen anti-HLA-B antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes
total:8
Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins. 2010 to the paper
R&D Systems anti-LEDGF/ p75 antibody was used to perform immunoprecipitation, immunocytochemistry, and western blot in order to study the regulation of HIV-1 DNA integration by viral Rev and cellular LEDGF/p75s interplay. more
total:5
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Santa Cruz anti-cyclin T1 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:1
PPAR? controls Dectin-1 expression required for host antifungal defense against Candida albicans. 2010 to the paper
eBioscience anti-SIGNR1 antibody was used in flow cytometry in order to investigate the role of PPARgamma in the regulation dectin-1 expression and host antifungal defense.
total:11
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK9 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:3
Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R. 2010 to the paper
Abcam anti-vprbr was used to perform western blot in order to study the chromosome copy-number alterations in cell cycle G2. more
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 to the paper
Invitrogen Purified goat IgG was used as the isotypic controls in order to identify the MHC I molecule (HLA-C) as an attachment factor in facilitating HCoV-HKU1 spike (S) mediated infection. more
total:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 to the paper
Santa Cruz Biotechnology anti-HLA-A(A-18) antibody was used to perform immunohistochemistry in order to study tumor and tumor-stromal cell interactions. more
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:9
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
R&D systems anti-CCR2 antibody (1:100) was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:1
Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle. 2008 to the paper
Sigma mouse monoclonal MHCf antibody was used in immunohistochemistry in order to study the role of talin 1 in the development and function of skeletal muscle
total:15
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-Tsg101 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-NUP was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:6
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
total:9
Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection. 2010 to the paper
Proteintech anti-CypA monoclonal antibody was used to perform western blot in order to study the role of HBV small surface protein(SHBs) in promoting the pathogenesis of HBV infection. more
total:4
Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. 2008 to the paper
Santa Cruz anti-Elongin B antibody was used in immunoprecipitation in order to demonstrate that SAP130 may link CRL mediated ubiquitination to gene expression. more
total:18
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Santa Cruz Goat polyclonal anti-CD63/LAMP3 Ab (clone M-13, 1:50) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
total:3
Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. 2009 to the paper
R&D Systems anti-CCL4 antibody was used for immunocytochemistry in order to show the placental transcriptome of VUE and identify VUE combines maternal allograft rejection and maternal antifetal graft-vs-host disease. more
total:22
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
AbD Serotec anti-TGN46 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:20
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
eBioscience anti-CD3 monoclonal antibody OKT3 was used to stimulate CD4+ T cell in order to study novel HIV-1 capture mechanism. more
total:5
HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system. 2007 to the paper
Abcam DDB1 antibody was used in western blot in order to study the potential role of the ubiquitin/proteasome system (UPS) in the ability of HIV-1 Vpr to induce G2 arrest. more
total:77
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Invitrogen anti-Phalloidin antibody was used to perform immunohistochemistry in order to study synaptic plasticity. more
total:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Santa Cruz Biotechnology CRM-1 antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport. more
total:7
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. 2009 to the paper
eBioscience antibodies against alpha4beta1 were used in immunohistochemistry to investigate MuPAR and plasmin in the regulation of the proliferation, marrow pool size, homing, engraftment, and mobilization of HSPCs and HSCs. more
total:2
BPAG1e maintains keratinocyte polarity through beta4 integrin-mediated modulation of Rac1 and cofilin activities. 2009 to the paper
Novus Biologicals anti-cofilin antibody was used for western blot in order to investigate the role of BPAG1e in the regulation the activities of Rac 1 and Cofilin more
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
total:43
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
eBioscience anti-CD3 antibody was used to perform cell culture in order to study how gut microbiota regulate immunesystem. more
total:11
The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide.. 2010 to the paper
PBL Laboratories anti-IFNalpha antibody was used in flow cytometry in order to investigate the role of VP35 Protein of Ebola Virus in the regulation of dendritic cell maturation induced by virus and lipopolysaccharide. more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more
total:2
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 to the paper
Cell Signaling ALIX antibody was used to perform western blot in order to indicate an important role for the ubiquitin ligase activity of HOIP in CD40 signaling. more
total:2
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Upstate CD85j antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo. more
total:48
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD3 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:12
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Serotec FITC-conjugated anti-MHC-I was used to perform flow cytometry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:3
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-CUL4A antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:1
Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. 2005 to the paper
Dr. Stephen Leeder (Mercy Children's Hospital) CYP3A5-specific polyclonal antibody was used in western blot to study the inhibition of CYP3A4 and CYP3A5 by verapamil
total:62
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IFN-gamma was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:3
Identification of small molecule activators of cryptochrome. 2012 to the paper
Millipore anti-actin was used to perform western blot in order to show that cryptochrome could be studied by specific small molecule activators. more