golgi apparatus
gene
reagent
sample publication
sample review
GORASP1
golgi reassembly stacking protein 1
total:2
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Santa Cruz Biotechnology anti-GRASP65 antibody was used to perform immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
GORASP2
golgi reassembly stacking protein 2
total:1
GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking. 2010 to the paper
Proteintech Group Inc rabbit polyclonal anti-GRASP55 antibody(Catalog No.: 10598-1-AP, 37ug/150 ul)was used to perform western blot and immunocytochemistry assays in order to demonstrate the molecular mechanisms of GRASP55 and GRASP65 in Golgi cisternal stacking.
GM130
golgin A2
total:61
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Abcam rabbit anti-Gm130 antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
ARF1
ADP ribosylation factor 1
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
LMAN1
lectin, mannose binding 1
total:4
Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. 2010 to the paper
Sigma rabbit polyclonal anti-ERGIC-53 antibody (1:1000) was used in western blot in order to study the regulation of autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. more
oxysterol binding protein
total:1
Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis. 2007 to the paper
Drs. Ignacio Rodriguez (NIH) rabbit polyclonal antibody against OSBP was used in western blot to study the role of OSBP in regulating of hepatic TG metabolism and insulin signaling pathways.
TRAPPC11
trafficking protein particle complex 11
SLC35C1
solute carrier family 35 member C1
p115
USO1 vesicle transport factor
total:5
SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development. 2006 to the paper
BD Biosciences Pharmingen mouse monoclonal p115 (clone 15, IgG1) antibody was used in immunocytochemistry to study the enrichment of SPG3A protein atlastin-1 in growth cones and its promotion of axon elongation during neuronal development. more
GOLGA5
golgin A5
total:1
Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells. 2005 to the paper
BD Biosciences anti-GS15 antibody was used in western blot to study the Subunit organization and function of the conserved oligomeric golgi (COG) complex.
PAQR3
progestin and adipoQ receptor family member 3
GCC2
GRIP and coiled-coil domain containing 2
TMED2
transmembrane p24 trafficking protein 2
syntaxin 6
total:7
The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005 to the paper
BD Transduction Laboratories mouse monoclonal antibody against syntaxin 6 was used in immunocytochemistry to study the function of a DnaJ domain-containing protein RME-8 in endosomal trafficking. more
NAPA
NSF attachment protein alpha
total:2
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-alphaSNAP antibody was used in immunocytochemistry to study the effects of interaction between G 12 and SNAP on VE-cadherin localization at endothelial junctions and barrier function. more
ARFGAP2
ADP ribosylation factor GTPase activating protein 2
ATP6V0A2
ATPase H+ transporting V0 subunit a2
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Molecular Probes mouse anti-Vph1 antibody (1:2000 dilution) was used to perform western blot in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
TRAPPC9
trafficking protein particle complex 9
total:2
Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. 2007 to the paper
Santa Cruz Biotechnology IKK beta antibody was used in immunoprecipitation to study the K13-induced NF-B and JNK activation and re-examine the role of TRAFs in these processes. more
VPS29
VPS29 retromer complex component
total:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 to the paper
Dr. Juan S. Bonifacino (National Institute of Child Health and Human Development) Vps29 antibody was used in western blot and immunoprecipitation to study the functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors
ARL1
ADP ribosylation factor like GTPase 1
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules
TGN46
trans-golgi network protein 2
total:22
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
AbD Serotec anti-TGN46 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
VPS35
VPS35 retromer complex component
total:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 to the paper
Dr. Juan S. Bonifacino (National Institute of Child Health and Human Development) Vps35 antibody was used in western blot and immunoprecipitation to study the functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors
SEC16A
SEC16 homolog A, endoplasmic reticulum export factor
PRKD1
protein kinase D1
total:15
Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton. 2005 to the paper
Santa Cruz Biotechnology protein kinase C mu (C-20) antibody was used in western blot to study amino acid-stimulated Ca2+ oscillations through a phospholipase c/inositol 1, 4, 5-trisphosphate-independent pathway. more
MYO6
myosin VI
total:2
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma mouse anti-myosin VI antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis. more
optineurin
total:3
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. 2011 to the paper
immunGlobe anti-OPTN was used to perform western blot and immunocytochemistry in order to show that Salmonella enterica growth was restricted by phosphorylation of autophagy receptor optineurin. more
SORT1
sortilin 1
total:3
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. 2005 to the paper
BD Biosciences anti-sortilin antibody was used in western blot and immunocytochemistry to study the role of sortilin in brain-derived neurotrophic factor secretory pathway more
PI4KA
phosphatidylinositol 4-kinase alpha
total:1
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Proteintech group Inc anti-PI4KCA antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation.
PLA2G4A
phospholipase A2 group IVA
total:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Santa Cruz Biotechnology anit-cPLA2a antibody was used to perform western blot and immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex. more
ATP7A
ATPase copper transporting alpha
total:5
Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells. 2008 to the paper
Santa Cruz Biotechnology goat anti-ATP7A antibody was used in immunocytochemistry in order to assess the relevance of sub cellular localization of the copper efflux transporters ATP7A and ATP7B for acquired cisplatin resistance in vitro. more
HCK
HCK proto-oncogene, Src family tyrosine kinase
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
MEK1
mitogen-activated protein kinase kinase 1
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
Clathrin Heavy Chain
clathrin heavy chain
total:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Millipore rabbit anti-Clathrin antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
furin
furin, paired basic amino acid cleaving enzyme
total:7
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
Thermo Fisher Scientific anti-furin antibody was used in immunocytochemistry in order to investigate the mechanism of the autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
CSF1R
colony stimulating factor 1 receptor
total:7
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. 2006 to the paper
Upstate (Millipore) rabbit anti-human CSF-1 R polyclonal antibody(06-457)was used to perform mmunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. more
BACE
beta-secretase 1
total:9
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-BACE1 was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
cdc42
cell division cycle 42
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
PCSK9
proprotein convertase subtilisin/kexin type 9
total:2
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 to the paper
Abcam goat anti-human PCSK9 polyclonal antibody (catalog #:Ab28770) was used to perform antibody-blocking experiments in order to demonstrate that PCSK9 specific antibodies can reverse the PCSK9-mediated down-regulation of cell-surface LDLRs. more
H-Ras
HRas proto-oncogene, GTPase
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
CLU
clusterin
total:6
Endothelin A receptor blockade influences apoptosis and cellular proliferation in the developing rat kidney. 2009 to the paper
Oncogene antibodies against clusterin were used in western blot to investigate the role of endothelin systems in the regulation of physiologic renal growth and development. more
Rab11
RAB11A, member RAS oncogene family
total:9
Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells. 2009 to the paper
Invitrogen rabbit polyclonal Rab11a antibody was used in western blot at 1:500 in order to investigate the function of Rab11 isoforms in regulating CFTR trafficking in T84 cells more
CD63
CD63 molecule
total:18
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Santa Cruz Goat polyclonal anti-CD63/LAMP3 Ab (clone M-13, 1:50) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more