fatty liver
gene
reagent
sample publication
sample review
PNPLA3
patatin like phospholipase domain containing 3
SREBP-1
sterol regulatory element binding transcription factor 1
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
PPAR
peroxisome proliferator activated receptor alpha
total:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 to the paper
Abcam rabbit polyclonal antibody PPAR was used for immunoprecipitation in order to study the circadian gene expression of integration of microRNA miR-122 in hepatic. more
adiponectin
adiponectin, C1Q and collagen domain containing
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
PLIN2
perilipin 2
total:2
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-ADRP antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
PPARgamma
peroxisome proliferator activated receptor gamma
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
AHSG
alpha 2-HS glycoprotein
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
R&D systems anti-fetuin A antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
PUMA
BCL2 binding component 3
total:12
Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer. 2008 to the paper
Calbiochem anti-PUMA antibody was used in western blot to study the mechanism and effect of p53 activation by a potent and specific MDM2 antagonist (MI-43) in colon cancer. more
cytokeratin 18
keratin 18
total:23
A lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays. 2013 to the paper
Abcam anti-keratin 18 antibody was used to perform western blot in order to investigate the mechanism of the pharmacological activity of PTC124. more
PPARGC1A
PPARG coactivator 1 alpha
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
visfatin
nicotinamide phosphoribosyltransferase
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
SREBF2
sterol regulatory element binding transcription factor 2
total:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 to the paper
Santa Cruz Biotechnology anti-SREBP2 antibody was used in western blot to study the effect of liver X receptor alpha on SREBP1c-mediated Abcd2 expression more
leptin receptor
total:9
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 to the paper
Santa Cruz Biotechnology OB-R antibodies (C-20: specific for long form of leptin receptor, H-300: for both long and short form of leptin receptor, mouse monoclonal B-3: for both long and short forms of leptin receptor) were used in immunoprecipitation (C-20 and H-300) and western blot (B-3) to study the recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 by leptin and its stimulation of breast cancer cells. more
KLF6
Kruppel like factor 6
total:3
Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. 2008 to the paper
Santa Cruz Biotechnology Inc Klf6 rabbit polyclonal antibodies were used to probe nitrocellulose blots in order to study differential regulation of Kr ppel-like factor family transcription factor expression in neonatal rat cardiac myocytes. more
IKK alpha
component of inhibitor of nuclear factor kappa B kinase complex
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
total:1
Quantitation and cellular localization of 11beta-HSD1 expression in murine thymus. 2006 to the paper
Dr. Zygmunt Krozowski (Baker Heart Research Institute) 11beta-HSD1 antibody was used in western blot to assess 11beta-HSD1 protein expression in whole tissues.