endoplasmic reticulum
gene
reagent
sample publication
sample review
Bip
heat shock protein family A (Hsp70) member 5
total:47
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Abcam GRP78/BiP rabbit polyclonal (1:25) was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
SYVN1
synoviolin 1
total:2
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Santa Cruz biotechnology anti-synoviolin mAb was used to perform immunocytochemistry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
VCP
valosin containing protein
total:14
The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97. 2008 to the paper
Progen Biotechnik GmbH anti-VCP/p97 monoclonal antibody was used to perform Western Blot in order to study the possible role of VCP/p97 in myelomonocytic differentiation and retrodifferentiation. more
STIM1
stromal interaction molecule 1
total:4
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Abnova anti-STIM1 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
total:1
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 to the paper
Axxora anti-SEL1L was used to perform western blot in order to demonstrate that OS-9 and XTP3-B/erlectin are ER-resident glycoproteins that bind to ERAD substrates and, via the SEL1L adaptor, to the ER membrane-embedded ubiquitin ligase Hrd1.
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10
XBP1
X-box binding protein 1
total:3
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
BioLegend anti-XBP1s antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
ERN1
endoplasmic reticulum to nucleus signaling 1
total:2
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. 2006 to the paper
Santa Cruz Biotechnology anti-IRE1alpha antibody was used in western blot to study the mechanism by which ER stress activates NF-kappaB and its role in regulation of ER stress-induced cell death in human cells. more
EDEM
ER degradation enhancing alpha-mannosidase like protein 1
OS9
OS9 endoplasmic reticulum lectin
total:1
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 to the paper
Abcam anti-OS-9 was used to perform western blot in order to demonstrate that OS-9 and XTP3-B/erlectin are ER-resident glycoproteins that bind to ERAD substrates and, via the SEL1L adaptor, to the ER membrane-embedded ubiquitin ligase Hrd1.
calnexin
total:75
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRF. 2013 to the paper
Santa Cruz Biotechnology rabbit anti-calnexin and goat anti-calnexin antibodies were used to perform western blot and immunocytochemistry in order to investigate the mechanism of self-cleavage of MYRF. more
PERK
eukaryotic translation initiation factor 2 alpha kinase 3
total:14
The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-PERK antibody was used in immunoprecipitation in order to demonstrate that UVB-induced eIF2 phosphorylation is regulated by NOS. more
DDIT3
DNA damage inducible transcript 3
total:17
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
ABR Affinity BioReagents anti-CHOP was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
ERO1A
endoplasmic reticulum oxidoreductase 1 alpha
SERPINA1
serpin family A member 1
total:5
Quantitative proteomic analysis by iTRAQ(R) for the identification of candidate biomarkers in ovarian cancer serum. 2010 to the paper
Abcam anti-alpha-1 antitrypsin antibody was used to perform western blot in order to study the identification of candidate biomarkers by iTRAQ® analysis in ovarian cancer serum. more
ETEA
Fas associated factor family member 2
total:1
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. 2008 to the paper
Imgenex anti-UBXD8 antibody was used to carry out western blot analysis in order to investigate the role for UBXD7-assembled p97 in the regulation of HIF1alpha degradation.
ATF4
activating transcription factor 4
total:11
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
Santa Cruz Biotechnologies anti-CREB-2 antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
UFD1
ubiquitin recognition factor in ER associated degradation 1
total:1
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. 2008 to the paper
BD Transduction Laboratories anti-UFD1 antibody was used to carry out western blot analysis in order to investigate the role for UBXD7-assembled p97 in the regulation of HIF1alpha degradation.
CASP4
caspase 4
total:4
The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. 2009 to the paper
MBL monoclonal anti-caspase-4 antibody (4B9) was used in western blot to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cells more
SEC62
SEC62 homolog, preprotein translocation factor
DERL2
derlin 2
total:2
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
MBL International anti-derlin-2 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
PRDX4
peroxiredoxin 4
total:1
Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells. 2006 to the paper
ACRIS PDX4 antibody was used in western blot to study its expression regulation in human myelomonocytic THP-1 cell lysate in response to NOD2 receptor activation by muramyl dipeptide
TMBIM6
transmembrane BAX inhibitor motif containing 6
CFTR
CF transmembrane conductance regulator
total:17
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Upstate Biotechnology mouse anti-CFTR antibody (clone M3A7) was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
PDI
protein disulfide isomerase family A member 2
total:18
Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism. 2008 to the paper
Stressgen Biotechnologies anti-PDI antibody was used in immunocytochemistry in order to study the roles of RhoBTB-dependent Cul3 ubiquitin ligase complexes more
TAP1
transporter 1, ATP binding cassette subfamily B member
DNAJB9
DnaJ heat shock protein family (Hsp40) member B9
Grp94
heat shock protein 90 beta family member 1
total:10
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Stressgen anti-GRP94 was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
SEC23A
Sec23 homolog A, COPII coat complex component
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
SEC24C
SEC24 homolog C, COPII coat complex component
DNAJB11
DnaJ heat shock protein family (Hsp40) member B11
LMAN1
lectin, mannose binding 1
total:4
Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. 2010 to the paper
Sigma rabbit polyclonal anti-ERGIC-53 antibody (1:1000) was used in western blot in order to study the regulation of autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. more
PSMD2
proteasome 26S subunit, non-ATPase 2
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
UBE2G2
ubiquitin conjugating enzyme E2 G2
total:1
Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation. 2008 to the paper
Abgent anti-UBE2G2 was used to perform western blot in order to show that autophagy is one of the mechanisms responsible for allozyme thiopurine S-methyltransferase (TPMT) *3A degradation.
GET3
guided entry of tail-anchored proteins factor 3, ATPase
calreticulin
total:39
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Stressgen anti-calreticulin antibody was used in western blot and immunocytochemistry to study the formation requirement of efficient hepatitis C virus particle. more
NPL4
NPL4 homolog, ubiquitin recognition factor
total:1
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. 2008 to the paper
Abnova anti-NPL4 antibody was used to carry out western blot analysis in order to investigate the role for UBXD7-assembled p97 in the regulation of HIF1alpha degradation.
SEC63
SEC63 homolog, protein translocation regulator
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
SERCA2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
total:10
Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. 2007 to the paper
Affinity BioReagents mouse anti-SERCA-2a antibody was used in western blot (1:1,000) to study the role of polycystin-2 in regulating ryanodine receptor-dependent calcium signaling. more
STT3B
STT3 oligosaccharyltransferase complex catalytic subunit B