dna damage
gene
reagent
sample publication
sample review
total:59
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
Santa Cruz anti-Chk1 monoclonal antibody was used to perform western blot in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1 infection. more
total:50
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore anti-phospho-ATM-S1981 antibody was used to perform immunofluorescence assay in order to detect the requirment of RSF1 for the recruitment of CENPS/MHF1, CENPX/MHF2, FANCD2, and FANCI to IRIF. more
total:24
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Santa Cruz human ATR antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:84
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Santa Cruz anti-PCNA was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:1
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. 2009 to the paper
Abcam POLH polyclonal antibody was used in western blot to study the role of TLS DNA polymerases eta and kappa in the regulation of naturally occurring DNA structures in human cancer cells.
total:7
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. 2011 to the paper
Abcam anti-MDC1 was used to perform immunocytochemistry in order to show that chromosomal structural aberrations could be caused by chromosome segregation errors. more
total:1
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-Rad18 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses.
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:1
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-DDB2 antibody was used to perform western blot in order to study the DNA damage and response by UV.
total:19
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Novus Biologicals polyclonal anti-53BP1 was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:175
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-PARP1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:9
RAS transformation requires CUX1-dependent repair of oxidative DNA damage. 2014 to the paper
Pierce anti-OGG1 antibody was used to perform Western Blotting in order to study CUX1-dependent repair of RAS-induced senescence. more
total:48
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. 2011 to the paper
Santa Cruz anti-chk2 was used to perform western blot and immunocytochemistry in order to show that chromosomal structural aberrations could be caused by chromosome segregation errors. more
total:14
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. 2009 to the paper
Santa Cruz Biotechnology anti-Tip60 antibody was used in western blot in order to explain that PDCD5 can maintain the histone acetyltransferase activity of the Tip60 protein and promote DNA damage-induced apoptosis as a Tip60 coactivator. more
total:12
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Millipore anti-DNA-PKcs antibody was used to perform western blot and immunofluorescence in order to study IRF-3-dependent innate immunity more
total:7
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-Rad9 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:5
HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system. 2007 to the paper
Abcam DDB1 antibody was used in western blot in order to study the potential role of the ubiquitin/proteasome system (UPS) in the ability of HIV-1 Vpr to induce G2 arrest. more
total:9
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
Novus Biological anti-FANCD2 polyclonal antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more
total:37
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Santa Cruz E2F1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:6
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Bethyl Laboratories rabbit anti-Claspin antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:28
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Novus NBS1 antibody was used to perform immunofluorescence assay in order to study the requirement of RSFI in DSB repair. more
total:12
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
GeneTex anti-RPA32 monoclonal antibody was used to perform immunofluorescence in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1 infection. more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:1
NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. 2009 to the paper
Bethyl anti-Rap80 antibody (BL2839) was used in western blot and immunoprecipitation to study the role for NBA1 in IR resistance, cell cycle regulation, and the recruitment of BRCA1 to sites of DNA damage.
total:19
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.. 2009 to the paper
Calbiochem rabbit polyclonal Mre11 antibody was used to perform western blot in order to investigate the relations between E1B-55K/E4orf6 and eIF2. more
total:1
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
R&D anti-ATRIP monoclonal antibody was used to perform immunofluorescence and western blot in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1. infection.
total:4
Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-?-TAK1-dependent mechanism. 2013 to the paper
Abcam HIPK2 antibody was used to perform ChIP in order to investigate the mechanism of the control of angiogenesis by transcriptional corepressors HIPK1 and HIPK2. more
total:20
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Calbiochem anti-Rad51 was used to perform immunocytochemistry in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:2
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-XPC antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:3
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Proteintech Group Cdt1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:6
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-TopBp1 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:4
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Santa Cruz anti-XPA antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:3
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Abcam anti-CUL4A antibody was used to perform western blot in order to study the DNA damage and response by UV. more
total:3
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Invitrogen anti-Ubc13 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.