diabetic nephropathies
gene
reagent
sample publication
sample review
total:3
The monocyte chemoattractant protein-1/cognate CC chemokine receptor 2 system affects cell motility in cultured human podocytes. 2007 to the paper
Progen Biotechnik polyclonal guinea pig anti-nephrin antibody was used in western blot in order to demonstrate cultured human podocytes express the CCR2 receptor and the MCP-1/CCR2 system can induce a migratory response in this cell type. more
total:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-ACE was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
total:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz rabbit anti-AT1 was used to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:5
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein. 2007 to the paper
Molecular Probes anti-pyruvate dehydrogenase antibody was used to perform western blot in order to study the interaction between SARS-CoV with Bcl-XL to result in cell apoptosis. more
total:5
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Alomone Labs anti-TRPC1 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:1
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 to the paper
R&D Systems goat anti-human L-FABP polyclonal antibody was used to perform western blot in order to study the prognostic ability of urinary liver-type fatty acid-binding protein (L-FABP) in Acute kidney injury (AKI).
total:3
The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3. 2008 to the paper
Sigma mouse monoclonal anti-alpha-actinin clone BM-75.2 was used to perform western blot and immunoprecipitation in order to study the interaction function between parafibromin and muscle alpha-actinins. more
total:5
Lipocalin 2 promotes breast cancer progression. 2009 to the paper
R&D Systems anti-human Lcn2 antibody was used in immunohistochemistry to study the effect of Lipocalin 2 on breast cancer progression. more
total:2
Host biomarkers and biological pathways that are associated with the expression of experimental cerebral malaria in mice. 2008 to the paper
Novus Biologicals anti-hemoglobin alpha1 antibody was used in western blot to identify novel host molecules in the brain that are affected in the course of the pathological manifestation of CM. more
total:4
Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. 2007 to the paper
Cedarlane Laboratories anti-human Tamm-Horsfall protein (THP) antibody was used in immunohistochemistry to localize broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney more
total:1
An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms. 2009 to the paper
Sigma rabbit anti-Podocin antibody was used to perform immunohistochemistry in order to study the role of the universal polarity protein, aPKC Lambda.
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 to the paper
Santa Cruz Biotechnology anti-HNF1B antibody was used for western blot in order to investigate the role of HNF-1beta in the regulation of PKD Modifier Gene Kif12. more
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
total:3
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Sigma anti-NMHC-IIA antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
total:7
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Sigma-Aldrich polyclonal rabbit anti-haptoglobin antibody (1:20,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:7
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-18 antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
total:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 to the paper
Abcam rabbit polyclonal anti-GLUT1 antibody was used to perform immunoblot in order to study the roles of the glucose deprivation during the development of KRAS pathway mutation. more
total:7
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
R&D Systems anti-Epo antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:9
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
Assay Designs anti-manganese superoxide dismutase antibody was used to perform western blot in order to study the interaction between F1L and endogenous Bak. more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:13
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-SIRT1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 to the paper
R&D Systems sandwich ELISA kit in which mouse anti-human OPG was employed as capture antibody and a biotinylated goat anti-human OPG used for detection to determine the concentration of OPG in the conditional medium of human vascular smooth muscle cells. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:4
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
Santa Cruz Biotechnology anti-Snail1 was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:16
An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans. 2009 to the paper
Stressgen anti-SOD1 antibody was used in western blot in order to demonstrate that locomotor defect associated with aggregation can be found in an ALS-linked mutant SOD1. more
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 to the paper
Novocastra Laboratories anti-HLA Class II (DR) was used to perform immunohistochemistry in order to show CD80 and CD86 may be potential nasopharyngeal carcinoma markers for clinical outcome.
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
total:30
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-ICAM-1 antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses. more