cystic fibrosis
gene
reagent
sample publication
sample review
CFTR
CF transmembrane conductance regulator
total:17
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Upstate Biotechnology mouse anti-CFTR antibody (clone M3A7) was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
CLCA1
chloride channel accessory 1
total:1
Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1. 2007 to the paper
Takeda Pharmaceutical polyclonal rabbit anti-CLCA1 antibody was used in western blot to study the effect of niflumic acid and AG-1478 on cigarette smoke-induced mucin synthesis
SCNN1G
sodium channel epithelial 1 subunit gamma
total:1
Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction. 2006 to the paper
Affinity Bioreagents anti-gammaENaC polyclonal antibody was used in western blot to detect gammaENaC in human H441 cells
ELANE
elastase, neutrophil expressed
total:11
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
Abcam anti-elastase antibody was used to perform western blot and immunocytochemistry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
IL-8
C-X-C motif chemokine ligand 8
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
SLC9A3R1
SLC9A3 regulator 1
total:10
NHERF-1: modulator of glioblastoma cell migration and invasion. 2009 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-NHERF-1 antibody (1:1000) was used for western blot in order to investigate the role of Neuroglian in the regulation of Lis1 localization in circulating immunosurveillance cells.. more
TLR5
toll like receptor 5
total:4
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal TLR5 antibody (2 ug/ml) was used in western blot in order to study the role of toll-Like receptors in the pathogenesis of lyme neuroborreliosis more
EDNRA
endothelin receptor type A
total:6
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz goat anti-ETA was used in 1:50 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
DEFB1
defensin beta 1
total:2
Nuclear hBD-1 accumulation in malignant salivary gland tumours. 2008 to the paper
Biologo hBD-1 antibody was used in immunohistochemistry in order to characterize proteins involved in cell cycle control more
MBL2
mannose binding lectin 2
total:4
High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates. 2006 to the paper
Sanquin biotinylated mouse-anti-MBL IgG 5E12 (10 ug/ml) was used in ELISA assay as the detection antibody to measure MBL in plasma to study the high prevalence of mannose-binding lectin (MBL) deficiency in premature neonates more
TLR2
toll like receptor 2
total:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 to the paper
Hycult Biotechnologies monoclonal anti-TLR2 was used to perform ELISA in order to show that Toll-like receptors in human and murine adipose tissue participate omental adipose tissue-related inflammation. more
TGM2
transglutaminase 2
total:7
RhoE Is required for keratinocyte differentiation and stratification. 2009 to the paper
Abcam rabbit polyclonal anti-transglutaminase antibody was used in western blot to study the role for RhoE in keratinocyte differentiation and stratification more
IL-17
interleukin 17A
total:19
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
eBioscience anti-IL-17A mAb was used to perform flow cytometry and cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
TLR4
toll like receptor 4
total:37
Role of Toll-like receptor 4 and human defensin 5 in primary endocervical epithelial cells. 2010 to the paper
R&D mouse monoclonal anti-TLR4 antibody was used to perform western blot in order to study the immune defence role of TLR4 and HD5 in primary endocervical epithelial cells. more
PPARgamma
peroxisome proliferator activated receptor gamma
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
TGF-beta1
transforming growth factor beta 1
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
ADRB2
adrenoceptor beta 2
total:7
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Santa Cruz Biotechnology anti-ADRB2 C-tail antibody was used to carry out western blot analysis in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
IL-1beta
interleukin 1 beta
total:30
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-1-beta mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
TCF7L2
transcription factor 7 like 2
total:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 to the paper
Upstate Biotechnology anti-TCF-4 antibody was used in immunoprecipitation and western blotting to investigate the action mechanism of the growth inhibition induced by bis[2-(acylamino)phenyl] disulfide. more
IGF-1
insulin like growth factor 1
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
PTGS2
prostaglandin-endoperoxide synthase 2
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
TNF-alpha
tumor necrosis factor
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
GSTP1
glutathione S-transferase pi 1
total:9
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. 2009 to the paper
Sigma mouse GG-7 Fc-specific anti-human IgG antibody was used to confirm the presence of the Fc fragment of human IgG in order to illustrate that Toll-like receptor 4 (TLR4) plays a fundamental role in the sensing of LPS from Gram-negative bacteria. more
GSTM1
glutathione S-transferase mu 1
total:2
Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients. 2008 to the paper
Lab Vision Corporation anti-GSTM antibody was used to perform immunocytochemistry in order to show that the expression of glutathione S-transferase pi is at a higher level in the brains of medically intractable epileptic patients. more
IL-10
interleukin 10
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
IL-6
interleukin 6
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more