cultured cells
gene
reagent
sample publication
sample review
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:62
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IFN-gamma was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:30
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-1-beta mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
total:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 to the paper
Hycult Biotechnologies monoclonal anti-TLR2 was used to perform ELISA in order to show that Toll-like receptors in human and murine adipose tissue participate omental adipose tissue-related inflammation. more
total:19
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
eBioscience anti-IL-17A mAb was used to perform flow cytometry and cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:30
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-ICAM-1 antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses. more
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:37
Role of Toll-like receptor 4 and human defensin 5 in primary endocervical epithelial cells. 2010 to the paper
R&D mouse monoclonal anti-TLR4 antibody was used to perform western blot in order to study the immune defence role of TLR4 and HD5 in primary endocervical epithelial cells. more
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:2
Mutational analysis reveals distinct features of the Nox4-p22 phox complex. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-Nox4 (7843) polyclonal antibody was used to perform western blot and immunocytochemistry in order to study the interaction of the key regulatory p22phox subunit with Nox4. more
total:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 to the paper
R&D systems rat anti-human ET-1 antibody (3G10) was used in immunohistochemistry to examine the distribution of eNOS and ET-1 in relation to vascular density represented by the endothelial marker CD31-immunoreactivity in skin tissue from amputated limbs of patients with CRPS. more
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
total:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 to the paper
BD Biosciences tissue factor antibody (CD142, clone number HTF-1) was used in western blot to detect its expression in culture medium and cell lysate from versican G3- or vector-transfected astrocytoma cell line U87 more
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:11
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. 2006 to the paper
Santa Cruz Biotechology anti-p110 gamma antibody was used in western blot in order to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 to the paper
Santa Cruz anti-Flk-1 antibody was used to perform immunoprecipitation in order to reveal the critical role of prorenin receptor and vacuolar H+-ATPase-mediated acidification in Wnt signaling. more
total:10
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-13 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR1 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
total:146
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Santa Cruz anti-p65 antibody was used to perform immunofluorescence in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:10
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
Stressgen anti-HO-1 antibody (1:500) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more