cos cells
gene
reagent
sample publication
sample review
total:52
Overcoming mutation-based resistance to antiandrogens with rational drug design. 2013 to the paper
Upstate anti-AR (PG-21) antibody was used to perform ChIP in order to study the rational drug design for castration-resistant prostate cancer without mutation-based resistance to antiandrogens. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:1
Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation. 2005 to the paper
Novocastra Laboratories monoclonal anti-TSHr antibody (AA 211 414) was used in immunocytochemistry to study TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy
total:4
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Affinity Biologicals sheep anti-factor V antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder. more
total:1
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Abcam polyclonal PAX 9 antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer.
total:40
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO1 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:20
Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus. 2009 to the paper
BD rat monoclonal antibodies against mouse Gr-l were used in flow immunocytometry to investigate the role of the migrant cDCs in the regulation of CD11c, MHC II, and CD86. more
total:3
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
ABCAM anti-FOXL2 antibody was used in immunocytochemistry in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more
total:1
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 to the paper
AbD Serotec rabbit anti-secretin receptor polyclonal antibody (1:1000) was used in western blot and immunohistochemistry to study secretin-receptor and secretin-receptor-variant expression in gastrinomas
total:4
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Abgent rabbit anti-JNK3 antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:7
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO2/3 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:5
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. 2007 to the paper
Affinity BioReagents anti-Cdc37 antibody was used in western blot in order to investigate the functions of Hsp40-related J-domain proteins DJA1, DJA2, and DJA4 during mitochondrial import. more
total:1
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 to the paper
Cell Signaling Technology phospho-Erk1 and Erk2 (phospho-p42/p44 MAPK) antibody was used in western blot in order to demonstrate that continuous GH induces CYP2C12 expression by activating Erk1 and Erk2 via the GHR
total:2
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. 2005 to the paper
Upstate Biotechnology GluR6 antibody was used in western blot to study cell-autonomous role of TrkB in the establishment of hippocampal Schaffer collateral synapses. more
total:2
ASIC3 in muscle mediates mechanical, but not heat, hyperalgesia associated with muscle inflammation. 2007 to the paper
Chemicon ASIC3 antibody was used in immunohistochemistry and elisa to study the role of ASIC3 in the development of cutaneous mechanical hyperalgesia induced by muscle inflammation. more
total:4
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. 2006 to the paper
Alpha Diagnostic monoclonal anti-OAT1 antibody was used in immunohistochemistry (diluted 1:500) to study the role of OAT1 in the "classical" organic anion secretory pathway. more
total:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 to the paper
Santa Cruz rabbit anti-Dbl antibody was used to perform immunoprecipitation and western blot in order to show that Nm23-H1 negatively regulate cell migration and tumor metastasis by modulating the activity of Dbl1.
total:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 to the paper
Affinity BioReagents polyclonal anti-beta arrestin 2 antibody was used in human embryonic kidney (HEK) 293 cells and in western blot to study the role of G protein-coupled receptor kinase site serine cluster in beta-arrestin-dependent beta2AR internalization and desensitization. more
total:1
Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. 2007 to the paper
Chemicon 1H9 antibody against ataxin-3 and 1C2 antibody directed against expanded polyglutamines were used in western blot and immunohistochemistry to study nuclear localization of ataxin-3 and its role in the manifestation of symptoms in SCA3
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:10
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
Santa Cruz anti-UBC9 antibody was used in western blot in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more
total:6
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Assay Biotech anti-phospho-HDAC5 (Ser498) antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 to the paper
BD Biosciences mouse monoclonal anti-TIF2 antibody was used in western blot (1:500) and immunohistochemistry (1:500) to assess the consequences of reducing expression of the transcription intermediary factor 2 (TIF2) coactivator on prostate cancer cell growth. more
total:2
Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. 2008 to the paper
Cell Signaling Technology anti-Smad6 antibody was used in western blot to elucidate the anti-mitogenic effect of a proteasome inhibitor in relation to BMP signalling in colon cancer. more
total:3
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Eps15 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
total:112
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-ERa antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:2
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GLA polyclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease. more
total:1
Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. 2009 to the paper
Abgent anti-Duox2 rabbit antibody was used to perform western blot in order to study the regulation of the localization of functional Duox-DuoxA heterodimers.
total:3
RhoE Is required for keratinocyte differentiation and stratification. 2009 to the paper
Millipore mouse monoclonal anti-RhoE antibody (4) was used in western blot to study the role for RhoE in keratinocyte differentiation and stratification more
total:20
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Santa Cruz Biotechnology anti-ERBB4 antibody was used in immunoprecipitation and western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:3
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-BMP-RIB was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
total:1
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. 2006 to the paper
Cell Signaling Technology rabbit polyclonal antibodies to Mst1 were used in western blot to detect Mst1 in human 293T and U2OS cell lines.
total:2
PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. 2007 to the paper
BD Transduction Laboratories anti-GGA3 monoclonal antibody was used to perform immunocytochemistry in order to investigate the relations between PI4P and GGA. more
total:1
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein. 2006 to the paper
Zymed Laboratories anti-SUMO3 antibody was used in western blot to detect SUMO3 in HEK293 cells co-transfected with His-SUMO isoforms (SUMO1, SUMO2, and SUMO3) and full-length human tau or alpha-synuclein.