chromatin
gene
reagent
sample publication
sample review
HOTAIR
HOX transcript antisense RNA
CTCF
CCCTC-binding factor
total:10
Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity. 2009 to the paper
Upstate rabbit polyclonal Ab anti-Ctcf was used in western blot in order to show that Parp1 and ADP-ribose polymers localize on the Dnmt1 promoter and Parp1 can protect its unmethylated state. more
PSIP1
PC4 and SFRS1 interacting protein 1
total:8
Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins. 2010 to the paper
R&D Systems anti-LEDGF/ p75 antibody was used to perform immunoprecipitation, immunocytochemistry, and western blot in order to study the regulation of HIV-1 DNA integration by viral Rev and cellular LEDGF/p75s interplay. more
H2AC20
H2A clustered histone 20
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
BRG1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
total:13
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB4 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
KDM1A
lysine demethylase 1A
total:4
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-LSD1 antibody was used to carry out immunoprecipitation assay and ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
BRD4
bromodomain containing 4
total:2
Association of bovine papillomavirus E2 protein with nuclear structures in vivo. 2005 to the paper
Abgent anti-Brd4 C terminus antibody was used to perform immunocytochemistry in order to study the interaction between E2 protein and structures in the nucleus. . more
RNF20
ring finger protein 20
total:1
Histone ubiquitination associates with BRCA1-dependent DNA damage response. 2009 to the paper
Bethyl anti-RNF20 antibody was used in immunoprecipitation in order to confirm that histone ubiquitination cause DNA damage.
PCNA
proliferating cell nuclear antigen
total:84
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Santa Cruz anti-PCNA was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
H2BC21
H2B clustered histone 21
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
CBX3
chromobox 3
total:5
Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins. 2009 to the paper
Proteintech Group anti-HP1 gamma antibody was used to perform western blot and immunohistochemistry in order to study the function of HP1 proteins in the alternative lengthening of telomeres-associated PML bodies by p53/p21. more
H3
H3 clustered histone 14
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
H3-4
H3.4 histone
total:17
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Millipore rabbit anti-pHH3 was used at 1:500 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
H3C1
H3 clustered histone 1
total:6
Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. 2011 to the paper
Abcam anti-dimethylated H3K9 antibody was used to perform ChIP in order to reveal the link between Clr4 and RNA quality control machinery. more
H2AZ1
H2A.Z variant histone 1
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
CBX5
chromobox 5
total:7
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 to the paper
Santa Cruz anti-HP1 antibody was used to perform western blot in order to study the DNA damage and response by UV. more
KCNQ1OT1
KCNQ1 opposite strand/antisense transcript 1
H4-16
H4 histone 16
total:4
Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones.. 2010 to the paper
Millipore anti-H4cit 3 antibody was used to perform western blot in order to study the role of PAD2 in citrullination of canine mammary epithelial cell histones. more
TP53BP1
tumor protein p53 binding protein 1
total:19
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Novus Biologicals polyclonal anti-53BP1 was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
CDT1
chromatin licensing and DNA replication factor 1
total:3
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Proteintech Group Cdt1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
HMGN1
high mobility group nucleosome binding domain 1
total:4
Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. 2006 to the paper
Michael Bustin (National Institutes of Health) anti-HMGN1 antibody was used in immunohistochemistry to study the expression relationship between HMGN1 and Sox9. more
Suz12
SUZ12 polycomb repressive complex 2 subunit
total:9
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-SUZ12 antibody was used to carry out ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more
H1-4
H1.4 linker histone, cluster member
total:2
The cell cycle timing of centromeric chromatin assembly in Drosophila meiosis is distinct from mitosis yet requires CAL1 and CENP-C. 2012 to the paper
Chemicon mouse anti-pan-histone antibody was used to perform immunostaining in order to study the cell cycle timing of CID assembly in mitosis and meiosis. more
CDC7
cell division cycle 7
total:1
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 to the paper
Neomarker Cdc7 antibody was used in immunoprecipitation to isolate Cdc7 from HeLa cells and in western blot to examine Cdc7 levels in HeLa.
KDM4A
lysine demethylase 4A
total:1
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. 2010 to the paper
Diagenode H3K9me3 antibody (# pAb-056-050) was used to perform ChIP assays in order to clarify that a KRAB domain-containing ZNF is involved in recruitment of the KAP1 and SETDB1 to specific regions of the human genome.
HDAC1
histone deacetylase 1
total:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-HDAC1 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
ATRX
ATRX chromatin remodeler
total:3
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. 2010 to the paper
Santa Cruz Biotechnology anti-ATRX was used to perform western-blot and immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3. more
FOXA1
forkhead box A1
total:4
Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium. 2009 to the paper
Santa Cruz FOXA1 antibody was used in western blot and immunohistochemistry to incubate membranes in order to investigate the role of TEAD1 and its cofactors YAP65 and FOXA2 in the regulation of the dysgenesis of the pigment epithelium. more
TOPBP1
DNA topoisomerase II binding protein 1
total:6
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-TopBp1 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
RAD18
RAD18 E3 ubiquitin protein ligase
total:1
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Bethyl anti-Rad18 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses.
H2AX
H2A.X variant histone
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
p300
E1A binding protein p300
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
DOT1L
DOT1 like histone lysine methyltransferase
total:1
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. 2008 to the paper
Bethyl anti-DOT1L antibody (A300-954A or 953A) was used in ChIP assay to study the recruitment of DOT1L and the patterning of mono-, di-, and trimethylation of H3K79 under dynamic conditions in human HEK293T cells.
TRIM28
tripartite motif containing 28
total:3
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. 2010 to the paper
Abcam KAP1 antibody (#ab3831) was used to perform ChIP assays in order to clarify that a KRAB domain-containing ZNF is involved in recruitment of the KAP1 and SETDB1 to specific regions of the human genome. more
MCM2
minichromosome maintenance complex component 2
total:8
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 to the paper
BD Biosciences antibody to total Mcm2 was used in western blot to examine the levels of total Mcm2 in HeLa cells. more
H4
H4 clustered histone 14
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
PARP
poly(ADP-ribose) polymerase 1
total:175
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-PARP1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more