chondrocytes
gene
reagent
sample publication
sample review
type II collagen
collagen type II alpha 1 chain
total:15
A stem cell-based approach to cartilage repair. 2012 to the paper
Abcam anti-type II collagen antibody was used to perform immunocytochemistry in order to show that kartogenin could be used to induce chondrocyte differentiation for osteoarthritis treatment. more
MMP13
matrix metallopeptidase 13
total:7
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-13 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
Sox9
SRY-box transcription factor 9
total:6
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. 2010 to the paper
Chemicon rabbit anti-Sox9 antibody (1:1000) was used in immunocytochemistry in order to investigate the role of beta-catenin in the regulation of Kras dependent reprogramming of acini into PDA preneoplastic precursors in mice. more
COL10A1
collagen type X alpha 1 chain
total:1
Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal collagen X antibody was used in immunohistochemistry to study the effects of rhSTC on collagen X expression in control and STC-treated metatarsal bones
cartilage oligomeric matrix protein
total:1
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. 2007 to the paper
Santa Cruz Biotechnology anti-COMP antibody was used in immunohistochemistry diluted at 1:200 to define the biological functions of COMP and its relationship with GEP.
ANKH
ANKH inorganic pyrophosphate transport regulator
aggrecan
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to study the expression of the ZIC family genes in different type of brain tumors. more
IL-1beta
interleukin 1 beta
total:30
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-1-beta mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
RUNX2
RUNX family transcription factor 2
total:16
Juvenile dermatomyositis calcifications selectively displayed markers of bone formation. 2009 to the paper
R&D Systems anti-Cbfa1 antibody was used to carry out immunohistochemistry assays in order to determine the presence of SIBLING protein and bone components in Juvenile Dermatomyositis pathologic calcifications. more
FGFR3
fibroblast growth factor receptor 3
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
GDF5
growth differentiation factor 5
total:2
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-GDF5 antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization. more
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
total:1
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. 2008 to the paper
Serotec ADAMTS-4 were used in western blot in order to study the effects of growth factors on the regulation of ADAMTS-4 expression
IHH
Indian hedgehog signaling molecule
total:2
Differential expression of runx2 and Indian hedgehog in cartilaginous tumors. 2007 to the paper
Santa Cruz goat polyclonal antibody C-15 against Ihh was used in immunohistochemistry to study the differential expression of runx2 and Indian hedgehog in cartilaginous tumors more
connective tissue growth factor
cellular communication network factor 2
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
ADAM15
ADAM metallopeptidase domain 15
total:4
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability. 2009 to the paper
Chemicon International ADAM-15 was used to recognize the C-terminus amino acid sequence RPAPPPPAASSLYL in order to study the mechanism of activin receptor signaling regulating prostatic epithelial cell adhesion and viability more
prostaglandin E synthase
total:9
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-mPGES-1 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
SIRT1
sirtuin 1
total:13
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-SIRT1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
MMP-3
matrix metallopeptidase 3
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
TGFB3
transforming growth factor beta 3
total:5
Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells. 2008 to the paper
Abcam rabbit anti-TGF-beta3 antibody (1:100) was used in immunocytochemistry in order to investigate the regulatory role of transforming growth factor-beta in valve interstitial cell function during wound repair more