centrosome
gene
reagent
sample publication
sample review
total:38
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Sigma-Aldrich rabbit anti-gamma tubulin was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
total:8
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. 2011 to the paper
Abcam anti-pericentrin antibody was used to perform immunocytochemistry in order to study the secretion of natural killer cell lytic granule at the immune synapse. more
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:1
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. 2010 to the paper
Biolegend rabbit anti-ninein antibody was used to perform immunofluorescence in order to investigate SDCCAG8 loss of function during heterogeneous single-gene disorders.
total:1
A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. 2010 to the paper
Sigma-Aldrich rabbit polyclonal anti-Odf2 antibody was used to carry out immunofluorescence assays in order to investigate the role for SEPT2 as diffusion barrier in the reguation of receptor-signaling pathways in the primary cilium.
total:1
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. 2005 to the paper
Santa Cruz anti-TTK antibody (sc-540) was used in human cells and in immunoprecipitation, western blot to study the role for the effect of TTK/hMps1 on CHK2 in the regulation of DNA damage checkpoint.
total:6
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
BD Transduction Laboratories anti-BUB1B antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
total:42
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Calbiochem anti-BRCA1 monoclonal antibody was used to perform immunoprecipitation in order to study the function of apicobasal polarity and regulation of stem cell in breast cancer more
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:1
Essential role of hIST1 in cytokinesis. 2009 to the paper
Abnova anti-alpha-CEP55 antibody was used to perform western blot in order to show that the hIST1 play an important role in cytokinesis.
total:20
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth.. 2008 to the paper
Epitomics anti-ATM antibody was used for western blot in order to investigate the role of Chk2 in the regulation of HSV-1 ICP0-mediated G2/M arrest and virus growth more
total:2
Differential regulation of centrosome integrity by DNA damage response proteins. 2008 to the paper
Proteintech anti-BRIT1 antibody was used to perform immunohistochemistry in order to study the functions of MDC1 and BRIT1 in the centrosome maturation and spindle assembly. more
total:1
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Abnova mouse monoclonal anti-MCAK antibody was used to carry out immunoblotting assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres.
total:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 to the paper
BD Biosciences mouse anti-Cdc25B antibody was used in western blot to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.
total:2
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
USBiological goat anti-TACC3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:1
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Proteintech Group rabbit anti-Nde1 antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation.
total:11
Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. 2010 to the paper
Zymed anti-NPM antibody was used for western blot in order to investigate the role for activated Bax in the regulation of p53-dependent, transcription-independent neural precursor cell apoptosis. more
total:59
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
Santa Cruz anti-Chk1 monoclonal antibody was used to perform western blot in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1 infection. more
total:61
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Abcam rabbit anti-Gm130 antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
total:44
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Millipore anti-CDK4 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:2
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Zymed anti-axin antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
total:19
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 to the paper
Spring Bioscience anti SMA antibody (1:100) was used to perform immunohistochemistry in order to study the function of pAkt on posterior capsule. more
total:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Millipore rabbit anti-Clathrin antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
total:4
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 to the paper
Santa Cruz Biotechnology goat anti-NuMA polyclonal antibody was used to perform western blot and immunoprecipitation assays in order to demonstrate that the interaction of NuMA with LANA plays a great role in KSHV genome maintenance and segregation. more
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
total:55
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-cyclin E antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:53
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk2 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:23
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Rockland anti-pT232 Aurora B was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:64
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Thermo Fisher Scientific anti-cyclin B1 monoclonal antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:9
Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells. 2009 to the paper
Invitrogen rabbit polyclonal Rab11a antibody was used in western blot at 1:500 in order to investigate the function of Rab11 isoforms in regulating CFTR trafficking in T84 cells more
total:10
FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. 2010 to the paper
EMD anti-BRCA2 antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex. more
total:6
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-p55CDC antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
total:2
Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death. 2005 to the paper
Santa Cruz Biotechnology anti-Pin-1 antibody was used in immunoprecipitation to study the interaction of tis21 protein with Pin-1 after phosphorylation of its Ser147 residue by p-Erk1/2. more
total:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Santa Cruz Biotechnology CRM-1 antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more