cd4 positive t lymphocytes
gene
reagent
sample publication
sample review
FOXP3
forkhead box P3
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
CD4
CD4 molecule
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
IL-17
interleukin 17A
total:19
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
eBioscience anti-IL-17A mAb was used to perform flow cytometry and cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
IL7R
interleukin 7 receptor
total:6
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
PDCD1
programmed cell death 1
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
CD25
interleukin 2 receptor subunit alpha
total:49
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 to the paper
eBioscience anti-CD25 antibody was used in flow cytometry in order to investigate the role of dendritic cells in the regulation of spontaneous fatal autoimmunity. more
IFN-gamma
interferon gamma
total:62
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IFN-gamma was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
CD70
CD70 molecule
total:1
CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production. 2010 to the paper
BD Biosciences anti-CD70 antibody was used in flow cytometry in order to investigate the role of CD27 in the regulation of IL2 production.
CCR5
C-C motif chemokine receptor 5 (gene/pseudogene)
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
IL-10
interleukin 10
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
CD28
CD28 molecule
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
T bet
T-box transcription factor 21
total:1
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Becton Dickinson anti-TBET antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem.
IL-7
interleukin 7
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
ITGAE
integrin subunit alpha E
total:2
Loss of CD103+ intestinal dendritic cells during colonic inflammation. 2010 to the paper
BD Pharmingen CD103 antibody was used for FACS analysis in order to investigate possible differences in dendritic cells within intestinal tissue of mice before and after induction of colitis. more
CTLA 4
cytotoxic T-lymphocyte associated protein 4
total:6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. 2011 to the paper
Santa Cruz anti-CTLA-4 antibody was used to perform immunocytochemistry in order to reveal the reason why CTLA-4 can inhibit CD28 stimulation. more
NY ESO 1
cancer/testis antigen 1B
total:2
Selective cancer-germline gene expression in pediatric brain tumors. 2008 to the paper
Zymed mouse monoclonal anti-NY-ESO-1 antibody was used in immunohistochemistry in order to study the expression of 12 CGGs in pediatric brain tumors and to identify targets for therapeutic cancer vaccines more
APOBEC3G
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
total:2
Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome. 2008 to the paper
Abgent rabbit polyclonal anti-C2orf37 antibody was used to perform immunohistochemistry in order to study the C2orf37 Mutations mediated Woodhouse-Sakati syndrome. more
CFL2
cofilin 2
total:2
BPAG1e maintains keratinocyte polarity through beta4 integrin-mediated modulation of Rac1 and cofilin activities. 2009 to the paper
Novus Biologicals anti-cofilin antibody was used for western blot in order to investigate the role of BPAG1e in the regulation the activities of Rac 1 and Cofilin more
DCAF1
DDB1 and CUL4 associated factor 1
total:3
Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R. 2010 to the paper
Abcam anti-vprbr was used to perform western blot in order to study the chromosome copy-number alterations in cell cycle G2. more
interleukin 2
total:17
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-2 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
HLA B
major histocompatibility complex, class I, B
total:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
PharMingen anti-HLA-B antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes