bone resorption
gene
reagent
sample publication
sample review
RANKL
TNF superfamily member 11
total:7
Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils. 2007 to the paper
R&D Systems monoclonal anti-human OPG antibody was used in elisa to study differential expression of RANK, RANK-L, and osteoprotegerin from patients with rheumatoid arthritis. more
ACP5
acid phosphatase 5, tartrate resistant
total:1
Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study. 2006 to the paper
Novocastra Laboratories Ltd. TRAP monoclonal antibody against against the N-terminal portion of human TRAP (clone: 26E5, subtype: IgG2b) was used in immunocytochemistry and immunohistochemistry to study the TRAP expression in various malignant and benign breast, ovarian, and melanoma tissues.
osteoprotegerin
TNF receptor superfamily member 11b
total:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 to the paper
R&D Systems sandwich ELISA kit in which mouse anti-human OPG was employed as capture antibody and a biotinylated goat anti-human OPG used for detection to determine the concentration of OPG in the conditional medium of human vascular smooth muscle cells. more
DKK1
dickkopf WNT signaling pathway inhibitor 1
total:5
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 to the paper
Abcam goat anti-human Dkk-1 anti-body was used to perform immunohistochemistry in order to investigate the expression alteration of dickkopfs (Dkks) and kremen2 (Krm2) in gastrointestinal cancer. more
TNFRSF11A
TNF receptor superfamily member 11a
total:2
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Abcam anti-RANK monoclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
osteocalcin
bone gamma-carboxyglutamate protein
total:2
Juvenile dermatomyositis calcifications selectively displayed markers of bone formation. 2009 to the paper
R&D Systems anti-OC antibody was used to carry out immunohistochemistry assays in order to determine the presence of SIBLING protein and bone components in Juvenile Dermatomyositis pathologic calcifications. more
type I collagen
collagen type I alpha 1 chain
total:21
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Abcam anti-collagen I antibody was used to perform immunohistochemistry and immunocytochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
IGF-1
insulin like growth factor 1
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
IL-6
interleukin 6
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more