blood platelets
gene
reagent
sample publication
sample review
CD41
integrin subunit alpha 2b
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
von Willebrand factor
total:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 to the paper
Serotec sheep anti-VWF was used to test von Willebrand factor (VWF) in order to research Rab27a and MyRIP's regulation to the amount and multimeric state of VWF released from endothelial cells. more
integrin beta3
integrin subunit beta 3
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
P-selectin
selectin P
total:8
Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept. 2008 to the paper
Santa Cruz Biotechnology anti-P-selectin antibody was used in immunohistochemistry at 1:500 in order to evaluate an in vivo role of TNF-alphaR1 on the pathogenesis of inflammatory diseases more
serotonin transporter
solute carrier family 6 member 4
total:2
Increased thalamocortical synaptic response and decreased layer IV innervation in GAP-43 knockout mice. 2007 to the paper
Immunostar 5-HTT antibody was used in western blot and immunohistochemistry to study the role of GAP-43 in regulating neurotransmitter release. more
CD40 ligand
total:13
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-CD40L antibody (1:200) was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
integrin alpha2
integrin subunit alpha 2
total:15
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
PEAR1
platelet endothelial aggregation receptor 1
VASP
vasodilator stimulated phosphoprotein
total:10
Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function. 2009 to the paper
Chemicon International rabbit polyclonal anti-VASP antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the roles of ADMA and DDAH in the regulation of pulmonary endothelial barrier function. more
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13
total:1
Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion. 2008 to the paper
Santa Cruz Biotechnology TTP antibody was used in immunocytochemistry in order to study the mechanism of persistent translation arrest
PPBP
pro-platelet basic protein
total:2
Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. 2010 to the paper
Santa Cruz goat polyclonal anti-PBP was used to perform western blot in order to show that function of factor H is defective in patients with systemic sclerosis and sclerodermatous GVHD. more
GP5
glycoprotein V platelet
total:3
Renewal of mural thrombus releases plasma markers and is involved in aortic abdominal aneurysm evolution. 2006 to the paper
Diagnostica Stago antibody against soluble glycoprotein V (sGPV) was used in ELISA to measure sGPV levels in plasma samples and eluates obtained from patients more
PTGS1
prostaglandin-endoperoxide synthase 1
total:12
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 to the paper
Santa Cruz anti-COX-1 antibody was used to perform western blot and immunohistochemistry in order to show that the cyclooxygenase-2 can leads to the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma. more
PF4
platelet factor 4
total:3
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. 2009 to the paper
Santa Cruz Biotechnology Mouse anti-platelet factor-4 polyclonal antibody was used to carry out western blot analysis in order to investigate the functionality of platelet TLR2 in the immune and inflammatory response. more
PAR-1
coagulation factor II thrombin receptor
total:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR1 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
ALOX12
arachidonate 12-lipoxygenase, 12S type
total:2
Role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. 2006 to the paper
Cayman Chemical 12-LO primary antibody was used in western blot to study the role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. more
factor V
coagulation factor V
total:4
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Affinity Biologicals sheep anti-factor V antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder. more
CPB2
carboxypeptidase B2
total:1
Development of sandwich-type ELISAs for the quantification of rat and murine thrombin activatable fibrinolysis inhibitor in plasma. 2008 to the paper
A. GILS (Katholieke Universiteit Leuven) TAFI antibody was used in elisa to develope an ELISA for the quantification of rat and murine TAFI in plasma.
CD36
CD36 molecule
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
tissue factor
coagulation factor III, tissue factor
total:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 to the paper
BD Biosciences tissue factor antibody (CD142, clone number HTF-1) was used in western blot to detect its expression in culture medium and cell lysate from versican G3- or vector-transfected astrocytoma cell line U87 more
F8
coagulation factor VIII
total:4
Expression of CD74, the receptor for macrophage migration inhibitory factor, in non-small cell lung cancer. 2009 to the paper
DAKO anti-Factor-VIII antibody (DAKO-EPOS) was used in immunohistochemistry to demonstrate whether the expression of CD74 is associated with the angiogenic activity and level of CXC chemokine expression in human specimens of non-small cell lung cancer. more
P2Y1
purinergic receptor P2Y1
total:2
Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments. 2008 to the paper
Alomone Labs anti-P2Y1 antibody was used in western blot to study the role for extracellular nucleotides in ectopic ossification of human spinal ligaments in human cells. more
MYH9
myosin heavy chain 9
total:3
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Sigma anti-NMHC-IIA antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
beta-tubulin
tubulin beta 1 class VI
total:25
Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. 2010 to the paper
Chemicon International mouse anti-beta tubulin antibody was used to carry out western blot analysis in order to investigate elastin-like polypeptide as carrier to target cell cycle inhibitory peptide for inhibiting ovarian cancer cell proliferation. more
CD32
Fc fragment of IgG receptor IIa
total:9
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-IgG antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
Syk
spleen associated tyrosine kinase
total:12
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.. 2008 to the paper
Santa Cruz Biotech anti-Syk antibody was used to perform western blot in order to study the interaction between NS5A and Syk. more
factor H
complement factor H
total:12
Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. 2010 to the paper
AbD Serotec mouse monoclonal anti-human FH was used to perform flow cytometry in order to show that function of factor H is defective in patients with systemic sclerosis and sclerodermatous GVHD. more
DNM3
dynamin 3
total:2
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef. 2007 to the paper
Affinity BioReagents anti-Dyn3 antibody was used in western blot in order to investigate the mechanism of how dynamin 2 (a binding partner of Nef) enhances the infectivity of HIV-1. more
EP3
prostaglandin E receptor 3
total:3
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP3 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
PDI
protein disulfide isomerase family A member 2
total:18
Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism. 2008 to the paper
Stressgen Biotechnologies anti-PDI antibody was used in immunocytochemistry in order to study the roles of RhoBTB-dependent Cul3 ubiquitin ligase complexes more
CD40
CD40 molecule
total:40
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-CD40 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
FCGR2B
Fc fragment of IgG receptor IIb
total:6
Loss of CD103+ intestinal dendritic cells during colonic inflammation. 2010 to the paper
BD Pharmingen CD32 antibody was used for FACS analysis in order to investigate possible differences in dendritic cells within intestinal tissue of mice before and after induction of colitis. more
CRP
C-reactive protein
total:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Abcam monoclonal anti-C-reactive protein (CRP) antibody was used in immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
STIM1
stromal interaction molecule 1
total:4
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Abnova anti-STIM1 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more