autoimmune diseases
gene
reagent
sample publication
sample review
total:17
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
eBioscience Alexa 647 anti-FoxP3 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. 2011 to the paper
Santa Cruz anti-CTLA-4 antibody was used to perform immunocytochemistry in order to reveal the reason why CTLA-4 can inhibit CD28 stimulation. more
total:49
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 to the paper
eBioscience anti-CD25 antibody was used in flow cytometry in order to investigate the role of dendritic cells in the regulation of spontaneous fatal autoimmunity. more
total:2
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. 2009 to the paper
Chemicon C4 monoclonal antibody was used in western blot to study the role of TLS DNA polymerases eta and kappa in the regulation of naturally occurring DNA structures in human cancer cells. more
total:4
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Biomedical Technologies anti-MHC antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
total:1
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression. 2008 to the paper
Santa Cruz goat polyclonal AIRE antibody was used in western blot in order to demonstrate that AIRE binds to histone H3 through its first PHD finger (AIRE PHD1)
total:10
Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation. 2007 to the paper
Santa Cruz Biotechnology anti-Stat4 antibody was used in ChIP assay to define a mechanism for Stat4-dependent genetic programming of a Th1-associated gene. more
total:5
Targeting A20 decreases glioma stem cell survival and tumor growth. 2010 to the paper
Abcam anti-A20 antibody was used for western blot and flow cytometry to study the function of A20 in glioma stem cell survival and tumor growth. more
total:3
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
Alexis polyclonal anti-TLR7 was used to perform flow cytometry and immunohistochemistry in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:4
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend anti-B7-H1 antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
total:17
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-2 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:1
Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo. 2010 to the paper
Abcam anti-human Lnk antibody was used for immunoblotting in order to demonstrate that Lnk leads to stabilization of thrombus development in vivo through regulating integrin alphaIIbbeta3 outside-in signaling in mouse platelets.
total:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 to the paper
Novocastra Laboratories anti-HLA Class II (DR) was used to perform immunohistochemistry in order to show CD80 and CD86 may be potential nasopharyngeal carcinoma markers for clinical outcome.
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:3
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 to the paper
Santa Cruz Biotechnology TRAF1 antibody (N-19) was used to perform western blot in order to indicate an important role for the ubiquitin ligase activity of HOIP in CD40 signaling. more
total:6
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems APC-labeled anti-IL-22mAb was used to perform flow cytometry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:19
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
eBioscience anti-IL-17A mAb was used to perform flow cytometry and cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
total:2
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
Alexis monoclonal PE-conjugated anti-TLR8 antibodies and anti-TLR8 were used to perform flow cytometry and immunohistochemistry respectively in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:3
Lack of disease specificity limits the usefulness of in vitro costimulation in HIV- and HCV-infected patients. 2008 to the paper
eBioscience agonistic anti-ICOS antibody (final concentration of 1 ug/mL) was used to treat cells in order to test the effects of IL-7/IL-15, IFN-alpha, anti-ICOS, and anti-CD28 on antigen-specific T cell responses in patients infected with HCV or HIV more
total:1
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. 2006 to the paper
Alexis rabbit polyclonal anti-Nalp3 antibody (which recognizes WT, R260W, and D303N cryopyrins) was used in human cells and in immunocytochemistry to study the role of cryopyrin and pyrin in activating caspase-1.
total:46
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Beckman-coulter PE-conjugated anti-CD11b was used to perform flow cytometry in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel mouse monoclonal antibody against C5b-9 was used in ELISA to study the association of the extracellular matrix and inflammation
total:1
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Chemicon International anti-IDO monoclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma.