atherosclerosis
gene
reagent
sample publication
sample review
phospholipid transfer protein
total:4
Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression. 2006 to the paper
Novus Biologicals polyclonal rabbit anti-mouse PLTP antibody was used in immunohistochemistry to assesse the impact of macrophage-derived phospholipid transfer protein (PLTP) on lesion development in hypercholesterolemic mice. more
apoA-I
apolipoprotein A1
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
ABCG1
ATP binding cassette subfamily G member 1
total:6
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-ABCG1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
SR-BI
scavenger receptor class B member 1
total:11
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-SR-B1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
ABCA1
ATP binding cassette subfamily A member 1
total:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Abcam mouse monoclonal anti-ABCA1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
CD36
CD36 molecule
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
CRP
C-reactive protein
total:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Abcam monoclonal anti-C-reactive protein (CRP) antibody was used in immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
LIPG
lipase G, endothelial type
total:1
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. 2009 to the paper
Novus Biologicals polyclonal anti-human EL antibody was used to carry out western blot analysis in order to clarify whether loss-of-function mutations in LIPG are associated with increased HDL-C levels.
apolipoprotein B
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
MCP-1
C-C motif chemokine ligand 2
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
myeloperoxidase
total:7
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. 2010 to the paper
Calbiochem anti-MPO (475915) antibody was used to perform immunohistochemistry in order to study the role of myeloperoxidase in the pathophysiology of atrial fibrillation. more
ICAM-1
intercellular adhesion molecule 1
total:30
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 to the paper
R&D systems anti-ICAM-1 antibody was used to perform immunocytochemistry in order to study the remodelling of cortical actin at natural killer cell immune synapses. more
endothelin 1
total:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 to the paper
R&D systems rat anti-human ET-1 antibody (3G10) was used in immunohistochemistry to examine the distribution of eNOS and ET-1 in relation to vascular density represented by the endothelial marker CD31-immunoreactivity in skin tissue from amputated limbs of patients with CRPS. more
NOX1
NADPH oxidase 1
total:1
Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart. 2007 to the paper
Transduction Laboratory antibody against Nox-1 was used in western blot to detect Nox-1 expression in human myocardial tissues.
FABP4
fatty acid binding protein 4
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
CX3CR1
C-X3-C motif chemokine receptor 1
total:3
Selective human endothelial cell activation by chemokines as a guide to cell homing. 2009 to the paper
EBioscience anti-chemokine (C-X3-C motif) receptor 1 rabbit IgG was used for flow cytometry in order to demonstrate that chemokines could activate human endothelial cell selectively as a guide to cell homing. more
CYBA
cytochrome b-245 alpha chain
total:4
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 to the paper
Novus Biologicals mouse anti-p22phox monoclonal antibody was used to perform Western blotting assays in order to study the molecular mechanisms of C-reactive protein in inhibiting cholesterol efflux from human foam cells. more
AGER
advanced glycosylation end-product specific receptor
NR4A3
nuclear receptor subfamily 4 group A member 3
adiponectin
adiponectin, C1Q and collagen domain containing
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
PLA2G2A
phospholipase A2 group IIA
total:5
Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16. 2005 to the paper
Upstate mouse monoclonal sPLA2 antibody was used in western blot to identify vitamin A-responsive genes in ocular surface epithelia. more
eNOS
nitric oxide synthase 3
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
PTX3
pentraxin 3
total:2
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Axxora PTX3 antibody (1:500) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity. more
hsp60
heat shock protein family D (Hsp60) member 1
total:21
Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. 2008 to the paper
Santa Cruz polyclonal anti-Hsp60 was used to perform immunocytochemistry in dilution 1:500 in order to show that acetylshikonin and analogues induce apoptosis through orphan nuclear receptor Nur77-mediated apoptotic pathway in cancer cells. more
P-selectin
selectin P
total:8
Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept. 2008 to the paper
Santa Cruz Biotechnology anti-P-selectin antibody was used in immunohistochemistry at 1:500 in order to evaluate an in vivo role of TNF-alphaR1 on the pathogenesis of inflammatory diseases more
PCSK9
proprotein convertase subtilisin/kexin type 9
total:2
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 to the paper
Abcam goat anti-human PCSK9 polyclonal antibody (catalog #:Ab28770) was used to perform antibody-blocking experiments in order to demonstrate that PCSK9 specific antibodies can reverse the PCSK9-mediated down-regulation of cell-surface LDLRs. more
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
total:1
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. 2008 to the paper
Serotec ADAMTS-4 were used in western blot in order to study the effects of growth factors on the regulation of ADAMTS-4 expression