amyotrophic lateral sclerosis
gene
reagent
sample publication
sample review
total:16
An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans. 2009 to the paper
Stressgen anti-SOD1 antibody was used in western blot in order to demonstrate that locomotor defect associated with aggregation can be found in an ALS-linked mutant SOD1. more
total:37
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps. 2010 to the paper
ABCAM anti-human TARDBP antibody(ab57105, 1.25 mg/ml) was used to perform western blot in order to introduce a new recombinase-mediated cassette exchange system that allows targeted insertion and conditional expression of any given genes. more
total:6
A yeast model of FUS/TLS-dependent cytotoxicity. 2011 to the paper
Abcam anti-FUS antibody (1:1000) was used to perform western blot in order to study the FUS/TLS-dependent cytotoxicity in yeast. more
total:3
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. 2011 to the paper
immunGlobe anti-OPTN was used to perform western blot and immunocytochemistry in order to show that Salmonella enterica growth was restricted by phosphorylation of autophagy receptor optineurin. more
total:1
RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1. 2009 to the paper
Sigma monoclonal mouse anti-TRN 1 antibody was used in blocking or activating expriments to study the effect of interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain on nucleocytoplasmic shuttling of ADAR1
total:4
Self-assembly of filopodia-like structures on supported lipid bilayers. 2010 to the paper
Axxora anti-profilin antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for how filopodia-like structures is self-assembled. more
total:3
Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. 2008 to the paper
BD-Biosciences KAP3 antibody was used in western blot (1:500) to investigate the role of kinesin-2 in pVHL mobility. more
total:2
Homeodomain transcription factor Phox2a, via cyclic AMP-mediated activation, induces p27Kip1 transcription, coordinating neural progenitor cell cycle exit and differentiation. 2006 to the paper
Chemicon peripherin antibody was used in immunohistochemistry to demonstrate the homeodomain transcription factor Phox2a coordinates cell cycle exit and differentiation by inducing p27 (Kip1) transcription. more
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
total:15
White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. 2008 to the paper
Covance anti-phosphorylated neurofilament antibody was used for western blot to elucidated the role of white matter tauopathy in frontotemporal lobar degeneration. more
total:14
The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97. 2008 to the paper
Progen Biotechnik GmbH anti-VCP/p97 monoclonal antibody was used to perform Western Blot in order to study the possible role of VCP/p97 in myelomonocytic differentiation and retrodifferentiation. more
total:14
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Santa Cruz anti-p62 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:1
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. 2011 to the paper
Abcam antibody mouse rabbit anti-CHMP2B antibody was used to perform immunohistochemistry in order to study quantification of CHMP2B on intercellular bridges at different stages.
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:7
Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy. 2010 to the paper
R&D Systems anti-human monoclonal/ biotinylated PGRN antibody was used to perform ELISA in order to study the progranulin's neuroprotective effect in vivo and therapeutic potential for motor axonopathy. more
total:20
The geometric structure of the brain fiber pathways. 2012 to the paper
Abcam mouse monoclonal anti-Neurofilament was used at 1:1000 to perform immunohistochemistry in order to show the architecture of the brain fiber pathways. more
total:1
Prox1 expression patterns in the developing and adult murine brain. 2007 to the paper
Chemicon NeuroN (1:100) antibody was used in immunohistochemistry to study the Prox1 expression patterns in the developing and adult murine brain.
total:32
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. 2010 to the paper
Sigma mouse-anti-SMN mAb was used to perform immunocytochemistry in order to clarify that TDP-43 transgenic and conditional knockout mouse models implicated a critical role of TDP-43 in pathways critical for motor neuron physiology and RNA processing. more
total:23
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
Zymed Laboratories chromogranin A antibody was used in immunohistochemistry in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:45
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Proteintech Group MAPT antibody (1:1500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more