alzheimer disease
gene
reagent
sample publication
sample review
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:12
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Chemicon rabbit anti-APP C-terminal antibody and mouse anti-APP (6E10) antibody were used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:45
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Proteintech Group MAPT antibody (1:1500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
total:9
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-BACE1 was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:5
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
BD Bioscience clathrin antibody was used to perform western blot in order to investigate internalization of ROR2 more
total:2
Mesenchymal stem cell-mediated functional tooth regeneration in swine. 2006 to the paper
Pharmingen/BD Bioscience R-PE conjugated monoclonal anti-human CD35 antibody was used in human mesenchymal stem cell and in flow cytometry to study the role for mesenchymal stem cell in tooth regeneration in swine. more
total:6
Endothelin A receptor blockade influences apoptosis and cellular proliferation in the developing rat kidney. 2009 to the paper
Oncogene antibodies against clusterin were used in western blot to investigate the role of endothelin systems in the regulation of physiologic renal growth and development. more
total:10
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Calbiochem rabbit anti-nicastrin antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:3
Stem cell antigen-1 localizes to lipid microdomains and associates with insulin degrading enzyme in skeletal myoblasts. 2008 to the paper
Calbiochem rabbit anti-IDE antibody was used in western blot in order to demonstrate that Sca-1 localizes to lipid microdomains in myogenic precursors and that it associates with a catalytically active intracellular messenger IDE more
total:6
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Upstate anti-Gab2 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:2
Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. 2006 to the paper
Sigma-Aldrich APP A8717 antibody was used in immunohistochemistry to study the roles for the FE65 amyloid precursor protein-interacting proteins in brain development. more
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
total:17
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Chemicon anti-Prion Protein was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
total:1
The endothelin-converting enzyme-1/endothelin-1 pathway plays a critical role in inflammation-associated premature delivery in a mouse model. 2008 to the paper
United States Biological anti-endothelin-converting enzyme-1 (ECE-1) antibody (0.5 ug/ml) was used in western blot in order to demonstrate that knockdown of ECE-1 mRNA leads to control of premature delivery in LPS-treated pregnant mice
total:8
Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime. 2010 to the paper
Millipore goat ChAT antibody was used to perform immunohistochemistry in order to clarify important roles of TDP-43 and FUS in motor neurons to the selectivity of the neurotoxicity. more
total:12
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD33 was used in 1.5ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Proteintech Group Inc anti-Dhcr24 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
total:1
Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation. 2006 to the paper
Alpha Diagnostic rabbit polyclonal antiserum (pAb, 7589, raised against a synthetic peptide, FDWEKAGTDALLST, of TTBK1308 321) was used in western blot to detect TTBK1 in mouse cortex, COS-7 cells and human HEK293 cells, and in immunocytochemistry to detect TTBK1 in COS-7 cells.
total:8
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Santa Cruz Biotechnology anti-Cdk5 (SC-173), Cdk5-pTyr-15 (SC-12918), and Cdk5-pSer-159 (SC-12919) antibodies were used to perform western blot in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 beta antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:7
Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy. 2010 to the paper
R&D Systems anti-human monoclonal/ biotinylated PGRN antibody was used to perform ELISA in order to study the progranulin's neuroprotective effect in vivo and therapeutic potential for motor axonopathy. more
total:11
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum. 2009 to the paper
Chemicon International antibodies against BDNF was used in immunohistochemistry in order to confirm the differential expression of neurotrophins in postnatal C57BL/6 mice striatum. more
total:1
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Invitrogen rabbit IgG was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models.
total:1
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. 2005 to the paper
BMA chicken BRI2 IgY polyclonal antibody was used in western blot and immunoprecipitation to investigate the binding of BRI2 to APP precursor protein.
total:1
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Sigma anti-TUBA monoclonal antibody was used to perform immunostaining in order to study the microtube density
total:2
Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death. 2005 to the paper
Santa Cruz Biotechnology anti-Pin-1 antibody was used in immunoprecipitation to study the interaction of tis21 protein with Pin-1 after phosphorylation of its Ser147 residue by p-Erk1/2. more
total:2
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Santa Cruz biotechnology anti-synoviolin mAb was used to perform immunocytochemistry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:1
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. 2005 to the paper
Calbiochem anti-APLP1 COOH-terminal polyclonal antibody was used in western blot and immunoprecipitation to investigate the binding of BRI2 to APP precursor protein.
total:5
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Upstate monoclonal anti-PP2A was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
total:2
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. 2008 to the paper
Santa Cruz Biotechnology nAChR alpha7 antibody was used in western blot in order to study the role of nAChR in the pathogenesis of choroidal neovascularization (CNV) more
total:4
ER tubules mark sites of mitochondrial division. 2011 to the paper
Abcam anti-Dnm1L was used to perform western blot in order to show that mitochondrial fission could be mediated by ER tubules. more
total:2
Apolipoprotein c1 association with hepatitis C virus. 2008 to the paper
U.S. Biologicals mouse monoclonal anti-apolipoprotein C1 antibody (A2299-59B) was used in flow cytometry to study the association of apolipoprotein C1 with hepatitis C virus. more
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:1
Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. 2010 to the paper
Abcam mouse anti-NEDD9 antibody was used to carry out immunofluorescence assays in order to investigate the role for transforming growth factor beta in regulating neuronal cell development.
total:33
Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. 2008 to the paper
Santa Cruz Biotechnology anti-alpha-syn mAb211 antibody was used to perform western blot in order to develop a cell modle of LB-associated neurodegeneration. more
total:5
Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. 2009 to the paper
Chemicon anti-Mint1 antibody was used to perform immunohistochemistry in order to study the roles of the amyloid precursor protein in peripheral and central synaptogenesis. . more
total:22
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD10 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:20
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. 2011 to the paper
Abcam anti-porin antibody was used to perform immunoprecipitation in order to reveal how viperin facilitates the infectious process. more
total:3
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal SAP antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
total:30
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.. 2009 to the paper
Epitomics rabbit monoclonal phospho-PKR antibody was used to perform western blot in order to investigate the relations between E1B-55K/E4orf6 and eIF2. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more