adenocarcinoma
gene
reagent
sample publication
sample review
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:7
The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL. 2009 to the paper
Zymed Laboratories mouse anti-ALK (1:4000, 4C5B8) antibody was used to study the role of ALK in the pathogenesis and the treatment of anaplastic large cell lymphoma. more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:11
Low-grade gastric adenomas/dysplasias: phenotypic expression, DNA ploidy pattern, and LOH at microsatellites linked to the APC gene. 2008 to the paper
Novocastra anti-Cdx2 monoclonal antibody(1:100) was used to perform immumohistochemistry in order to study phenotypic expression, DNA ploidy pattern, and LOH of the APC gene linked microsatellites. more
total:6
Characterizing the cancer genome in lung adenocarcinoma. 2007 to the paper
Santa Cruz Biotechnology anti-NKX2-1 polyclonal antibody was used to perform western blot in order to study the chromosome copy-number alterations in primary lung adenocarcinomas. more
total:129
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Invitrogen rat anti-E-Cadherin (ECCD-2; 13-1900) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:49
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-p19 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:40
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Santa Cruz Biotechnology PE-conjugated anti-IGF-1R antibody was used in flow cytometry to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:24
Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men. 2008 to the paper
Calbiochem anti-MLH1 antibody (1:75) was used to perform western blot and immunoprecipitation in order to study the function of small ubiquitin-related modifier (SUMO) 1, SUMO-2/3 and SUMOylation. more
total:3
Tumorigenic and metastatic activity of human thyroid cancer stem cells. 2010 to the paper
Novocastra anti-TTF1 antibody was used to perform immunohistochemistry in order to find out what activities of human thyroid cancer stem cells could be potential targets to treat thyroid carcinoma. more
total:27
Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon. 2009 to the paper
Dako Cytomation anti-pan-Cytokeratin antibody was used in immunohistochemistry to define the importance and role of cortactin in HNSCC tumor progression more
total:3
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Dako anti-AMACR(13H4) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
total:21
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-OCT4 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
total:10
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 to the paper
Calbiochem anti-TERT antibody (1:350) was used to perform immunohistochemistry in order to study the function of pAkt on posterior capsule more
total:8
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 to the paper
BD Biosciences antibody to total Mcm2 was used in western blot to examine the levels of total Mcm2 in HeLa cells. more
total:26
Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation. 2014 to the paper
Santa Cruz Biotechnology anti-p63 antibody was used to perform immunohistochemistry in order to study TNFa/TNFR2 axis protective role for skin against DUOX1-mediated oxidative stress. more
total:8
Reactivity with TdT in Merkel cell carcinoma: a potential diagnostic pitfall. 2008 to the paper
Dako anti-Cytokeratin 20(Ks20.8) antibody was used to perform immunohistochemistry in order to study the spectrum of immunoreactivity with TdT in MCC. more
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
total:1
Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance. 2009 to the paper
Abgent anti-ENT1 polyclonal antibody was used to perform western blot in order to understand the ribavirin uptake and cell-based mechanisms of ribavirin resistance.
total:1
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 to the paper
Active Motif rabbit polyclonal anti-RUNX3 antibody was used in immunocytochemistry to study the interaction between E4orf6, E1B-55K, and RUNX1 and the association of the RUNX1 with centers of viral DNA and RNA synthesis.
total:2
Epithelial nitration by a peroxidase/NOX5 system mediates mosquito antiplasmodial immunity. 2012 to the paper
Sigma Aldrich rabbit monoclonal anti-NOX5 was used to perform immunohistochemistry in order to show that antiplasmodial immunity in mosquitos is mediated by peroxidase/NOX5 System-dependent epithelial nitration. more
total:5
The clinicopathological and prognostic significance of MUC-1 expression in Japanese gastric carcinomas: an immunohistochemical study of tissue microarrays. 2008 to the paper
NovoCastra anti-human MUC-4 antibody was used to perform immunohistochemistry in order to study the clinicopathological significance of MUC-1 expression in gastric carcinomas. more
total:8
Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. 2008 to the paper
Oncogene Research Products rabbit polyclonal anti-human maspin antibody was used in immunocytochemistry to determine whether DNA methylation of the maspin promoter and histone H3 dimethylation are involved in the mechanism of down regulation of maspin synthesis in human corneal stromal fibroblasts and myofibroblasts. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:8
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. 2006 to the paper
Santa cruz biotechnology anti-Muc2 antibody was used to perform mmunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. more
total:5
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
BD anti-pan-MCM antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 to the paper
Abcam rabbit polyclonal anti-GLUT1 antibody was used to perform immunoblot in order to study the roles of the glucose deprivation during the development of KRAS pathway mutation. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:3
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:33
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Novus Biologicals rabbit polyclonal anti-Survivin antibody was used to carry out western blot analysis in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:2
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Epitomics anti-Aldh1 antibody (1:150) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:9
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. 2010 to the paper
Santa Cruz Biotechnology anti-MMP7 antibody was used in immunohistochemistry to investigate the function of UPK1A in esophageal squamous cell carcinoma. more
total:19
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. 2009 to the paper
Abcam polyclonal anti-CD133 antibody was used for western blot in order to identify the role of MT1-MMP for the regulation of COX-2 expression in CD133 (+) U87 glioblastoma cells. more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:18
Valproic acid resensitizes cisplatin-resistant ovarian cancer cells. 2008 to the paper
Transduction Laboratories anti-hMSH2 antibody was used in immunocytochemistry to show the effect of VPA and cisplatin on ovarian cancer cells. more
total:2
Aquaporin-3 expression in human fetal airway epithelial progenitor cells. 2005 to the paper
Alomone rabbit polyclonal anti-aquaporin channel 3 (antiAQP3) antibody was used in immunohistochemistry and flow cytometry to study the progenitor potentialities of human fetal basal and suprabasal airway epithelial cells. more
total:10
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Neomarkers anti-MUC5AC antibody was used to perform western blot and immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
total:1
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. 2007 to the paper
Abgent Monoclonal anti-His antibody was used to perform immunoprecipitation in order to investigate the role of human Tim-Tipin complex during the UV-induced intra-S checkpoint.
total:1
Essential role of hIST1 in cytokinesis. 2009 to the paper
ProteinTech Group anti-alpha-IST1 antibody was used to perform western blot in order to show that the hIST1 play an important role in cytokinesis.
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:2
An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients. 2007 to the paper
Chemicon International mouse monoclonal anti-RRM1 (1:500) antibody was used in western blot to study the association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients more
total:6
Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML). 2008 to the paper
Calbiochem anti-AQP5 antibody was used in immunohistochemistry to study the role for human AQP5 in the progression of chronic myelogenous leukemia in paraffin sections from human bronchial carcinoma tissues and normal bone marrow. more
total:12
Tumorigenic and metastatic activity of human thyroid cancer stem cells. 2010 to the paper
Dako anti-cytokeratin 19 antibody was used to perform immunohistochemistry in order to find out what activities of human thyroid cancer stem cells could be potential targets to treat thyroid carcinoma. more
total:6
Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells. 2005 to the paper
Zymed Laboratories mouse anti-claudin-4 monoclonal antibody was used in western blot and immunoprecipitation to study that phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction carrier function in ovarian cancer cells. more
total:4
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 to the paper
Chemicon MMP-11 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury. more
total:7
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. 2010 to the paper
Invitrogen anti-ANXA1 andibody was used to perform immnunohistochemistry, western blot and ELISA in order to study the functions of Annexin A1 in the anti-inflammatory and neuroprotective role of microglia. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:129
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
AbCam anti-Ki67 was used to perform immunohistochemistry in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
total:1
The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. 2005 to the paper
Dako polyclonal S100A2 (anti-S100A2) antibody was used in immunohistochemistry, immunocytochemistry, western blot, and immunoprecipitation to study the interaction between calcium-binding protein S100A2 and p53
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:24
Estrogen receptor beta-mediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma. 2009 to the paper
GeneTex mouse monoclonal anti-ER antibody (C14C8) was used in immunohistochemistry, immunocytochemistry, and immunoprecipitation to study the effect of estrogen receptormediated nuclear interaction between IRS-1 and Rad51 on homologous recombination directed DNA repair in medulloblastoma. more
total:3
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity. 2009 to the paper
Abgent rabbit anti-DCK was used to perform western blot in order to show that resistance to cytarabine arabinoside is associated with population-specific genetic variants. more
total:1
Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators. 2005 to the paper
Cayman chemical rabbit polyclonal FP receptor antibody was used in western blot to determine FP protein expression in hUSM cells
total:37
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Chemicon anti-B-Tubulin antibody was used to perform immunohistochemistry in order to study synaptic plasticity. more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:4
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. 2009 to the paper
Abcam anti-Prdx1 antibody was used for western blot in order to investigate the role of Prdx1 in the regulation of tumorigenesis. more
total:9
RAS transformation requires CUX1-dependent repair of oxidative DNA damage. 2014 to the paper
Pierce anti-OGG1 antibody was used to perform Western Blotting in order to study CUX1-dependent repair of RAS-induced senescence. more
total:10
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics anti-VEGF antibody (1:1000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:2
Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. 2008 to the paper
Proteintech Group polyclonal anti-human SM22 alpha antibody was used for western blot in order to show that ILK can regulate airway smooth muscle differentiation. more
total:20
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Abcam anit-keratin 5 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more