activated TAK1 mediates p38 MAPK activation
gene
reagent
sample publication
sample review
IKKgamma
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
IRAK
interleukin 1 receptor associated kinase 1
total:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Santa Cruz mouse anti-IRAK-1 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
MAPK11
mitogen-activated protein kinase 11
total:10
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Cell Signaling Technologies phospho-specific and total anti-p38antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
MK2
MAPK activated protein kinase 2
total:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
MKK3
mitogen-activated protein kinase kinase 3
total:15
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. 2008 to the paper
Cell Signaling Technology polyclonal rabbit MKK3 with phosphorylated serine 189 antibody was used in western blot in order to demonstrate that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human immunodeficiency virus-1 (HIV-1) in vitro more
MKK6
mitogen-activated protein kinase kinase 6
total:9
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. 2008 to the paper
Cell Signaling Technology polyclonal rabbit MKK6 with phosphorylated serine 207 antibody was used in western blot in order to demonstrate that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human immunodeficiency virus-1 (HIV-1) in vitro more
NOD1
nucleotide binding oligomerization domain containing 1
NOD2
nucleotide binding oligomerization domain containing 2
total:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 to the paper
Cayman Chemical NOD2-specific rabbit antiserum was used in immunoprecipitation and western blot to measure its expression in primary keratinocytes and transfected HEK293 cells. more
p38
mitogen-activated protein kinase 14
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1
total:5
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz goat anti-Tab1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
total:2
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TAB2 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Tak1
mitogen-activated protein kinase kinase kinase 7
total:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz mouse anti-Tak1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
TRAF6
TNF receptor associated factor 6
total:17
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF6 (H-274) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more