ZBP1(DAI) mediated induction of type I IFNs
gene
reagent
sample publication
sample review
DLM 1
Z-DNA binding protein 1
IkappaBalpha
NFKB inhibitor alpha
total:117
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
Santa Cruz anti-I-kappa B alpha antibody was used to perform western blot in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
IKK alpha
component of inhibitor of nuclear factor kappa B kinase complex
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
IKKbeta
inhibitor of nuclear factor kappa B kinase subunit beta
total:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Millipore anti-IKK2 antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
IKKgamma
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
IRF-3
interferon regulatory factor 3
total:22
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Life Technologies anti-IRF-3antibody was used to perform western blot in order to study IRF-3-dependent innate immunity more
NFKB2
nuclear factor kappa B subunit 2
total:11
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
New England Biolabs anti-p52/p100 (18D10) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
NFKBIB
NFKB inhibitor beta
total:7
A critical role for CHIP in the aggresome pathway. 2009 to the paper
Santa Cruz NFKBIB antibody was used for Western blotting in order to study the critical role for CHIP in the aggresome pathway. more
p50
nuclear factor kappa B subunit 1
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
p65
RELA proto-oncogene, NF-kB subunit
total:146
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Santa Cruz anti-p65 antibody was used to perform immunofluorescence in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
RIP
receptor interacting serine/threonine kinase 1
total:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-RIP antibody was used in western blot to study the effect of repression of NF-kB and activation of AP-1 on apoptosis in prostate cancer cells. more
TBK1
TANK binding kinase 1
total:7
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. 2011 to the paper
Epitomics anti-pTBK1pS172 was used to perform western blot in order to show that Salmonella enterica growth was restricted by phosphorylation of autophagy receptor optineurin. more