Unfolded Protein Response (UPR)
gene
reagent
sample publication
sample review
total:7
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Calbiochem anti-ATF3(c-19) antibody was used to perform western blot in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
total:11
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
Santa Cruz Biotechnologies anti-CREB-2 antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Abcam anti-ATP6V0D1 was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:47
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Abcam GRP78/BiP rabbit polyclonal (1:25) was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:39
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Stressgen anti-calreticulin antibody was used in western blot and immunocytochemistry to study the formation requirement of efficient hepatitis C virus particle. more
total:17
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
ABR Affinity BioReagents anti-CHOP was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:43
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Abcam anti-eIF2alpha was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:2
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. 2006 to the paper
Santa Cruz Biotechnology anti-IRE1alpha antibody was used in western blot to study the mechanism by which ER stress activates NF-kappaB and its role in regulation of ER stress-induced cell death in human cells. more
total:3
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. 2009 to the paper
Abcam membrin antibody was used in immunocytochemistry in order to investigate the role of SNARE complex containing VAMP7 and Vti1a in the regulation of a novel traffic pathway to the cell surface in both neuronal and non-neuronal cells. more
total:10
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Stressgen anti-GRP94 was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:23
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 alpha antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:1
Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer. 2010 to the paper
Proteintech Inc rabbit anti-human HDGF antibody(1:100) was used to perform immunohistochemistry in order to study the role of overexpressed HDGF in prognosis in Chinese patients with liver cancer.
total:2
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Abgent anti-Herp antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:57
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Santa Cruz lamin A/C goat polyclonal (1:1000)was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:14
The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-PERK antibody was used in immunoprecipitation in order to demonstrate that UVB-induced eIF2 phosphorylation is regulated by NOS. more
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:2
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Santa Cruz biotechnology anti-synoviolin mAb was used to perform immunocytochemistry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
total:1
Functional dissection of human and mouse POT1 proteins. 2009 to the paper
Sigma rabbit anti-humanTPP1 (1151) antibody was used in western blot in order to investigate the function of single-stranded telomeric DNA associated protein-POT1 in human and mice.
total:3
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
BioLegend anti-XBP1s antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
total:3
Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1. 2009 to the paper
Santa Cruz Biotechnology Miz-1 (N17) was used in coimmunoprecipitation assays in order to study the mechanism of Gfi-1 repressing CDKN2B and then encoding p15INK4B through interaction with Miz-1 more