Tumore necrosis facto receptor superfamily
gene
reagent
sample publication
sample review
CD27
CD27 molecule
total:12
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. 2011 to the paper
Beckman Coulter anti-CD27-APC-AlexaFluor700 was used to perform flow cytometry in order to show that HIV neutralizing antibodies evolved to recognize an invariant viral structure. more
CD40
CD40 molecule
total:40
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-CD40 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
Fas
Fas cell surface death receptor
total:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology FAS antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
lymphotoxin beta receptor
total:2
Parenteral nutrition impairs gut-associated lymphoid tissue and mucosal immunity by reducing lymphotoxin Beta receptor expression. 2006 to the paper
R&D Systems goat anti-LTbetaR antibody was used in western blot to determine the effects of parenteral nutrition (PN) on LTbetaR in gut-associated lymphoid tissue. more
p75NTR
nerve growth factor receptor
total:17
Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. 2008 to the paper
Novus Biologicals anti-p75NTR antibody was used to perform immunocytochemistry in order to show that cellular phenotype can be changed after exposure to acid and bile salt in Barrett's epithelial cell line. more
TNFR1
TNF receptor superfamily member 1A
total:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 to the paper
Santa Cruz anti-TNFR1 antibody was used to perform western blot in order to study the mechanism that TRAF2 inhibits stress-induced cell death. more
TNFR2
TNF receptor superfamily member 1B
total:14
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Stressgen Bioreagents TNFR2 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
TNFRSF6B
TNF receptor superfamily member 6b
total:2
Epstein-Barr virus transcription activator Rta upregulates decoy receptor 3 expression by binding to its promoter.. 2007 to the paper
BioLegend DcR3 antibody was used in western blot to demonstrate enhanced DcR3 expression upon EBV reactivation in P3HR1 cells and in EBV-infected 293 cells. more
CD30
TNF receptor superfamily member 8
total:10
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
Immunotech/Coulter anti-CD30 antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes more
4 1BB
TNF receptor superfamily member 9
total:3
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Santa Cruz Biotechnology polyclonal anti-CD137/4-1 BB(N-16) antibody was used to perform flow cytometric analysis in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
DR4
TNF receptor superfamily member 10a
total:10
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Diaclone mouse monoclonal anti-DR4 antibody (B-N28) was used to perform western blot in order to study the function of the natural product honokiol. more
DR5
TNF receptor superfamily member 10b
total:15
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 to the paper
eBioscience rabbit polyclonal anti-DR5 antibody was used in flow cytometry in order to investigate the roles of Fas ligand and TRAIL in the regulation of murine thymic graft-versus-host disease. more
TNFRSF10C
TNF receptor superfamily member 10c
total:1
Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. 2005 to the paper
Alexis anti-DcR1 (HS301) antibody was used in flow cytometry to study the biological function of TRAIL induced apoptosis in human colon cells.
TNFRSF10D
TNF receptor superfamily member 10d
total:3
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. 2010 to the paper
Stressgen DcR2 antibody was used in immunohistochemistry in order to show the importance of protection of the ATM-mediated DDR-p53 signaling pathway for breast cancer prevention. more
TNFRSF11A
TNF receptor superfamily member 11a
total:2
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Abcam anti-RANK monoclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
osteoprotegerin
TNF receptor superfamily member 11b
total:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 to the paper
R&D Systems sandwich ELISA kit in which mouse anti-human OPG was employed as capture antibody and a biotinylated goat anti-human OPG used for detection to determine the concentration of OPG in the conditional medium of human vascular smooth muscle cells. more
TNFRSF12A
TNF receptor superfamily member 12A
total:1
Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi's sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression. 2010 to the paper
Cell Signaling anti-TWEAKR antibody was used to perform western blot in order to study the mechanism by which KSHV miRNA prevented TWEAK-induced apoptosis and proinflammatory response.
TACI
TNF receptor superfamily member 13B
total:3
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. 2009 to the paper
Peprotech EC biotinylated polyclonal goat anti-human TACI antibody was used to carry out flow cytometry analysis in order to evaluate the genetic, immunologic, and clinical condition of patients with different TNFRSF13B variants. more
BCMA
TNF receptor superfamily member 17
total:2
Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. 2005 to the paper
R&D Systems anti BCMA antibody was used in western blot and flow cytometry to study graft-versus-tumor response in patients with multiple myeloma more
GITR
TNF receptor superfamily member 18
total:3
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-GITR antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more