Transcriptional regulation of white adipocyte differentiation
gene
reagent
sample publication
sample review
total:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 to the paper
Calbiochem rabbit polyclonal antibody against adiponectin was used in western blot and immunoprecipitation to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation. more
total:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 to the paper
Karen S. L. Lam (University of Hong Kong, China) monoclonal ANGPTL4 antibody was used in ELISA to study its effect in mice
total:21
C/EBPalpha or C/EBPalpha oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-kappaB p50 bound to the bcl-2 and FLIP gene promoters. 2009 to the paper
Affinity Bioreagents mouse anti-C/EBPa antibody was used to carry out immunoprecipitation assay and western blot analysis in order to investigate the mechanism for oncoprotein C/EBPa cooperated with NF-kB p50 to inhibit apoptosis. more
total:26
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology C/EBPbeta antibody was used in ChIP assay to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs). more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:5
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK8 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-C/EBP delta antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
total:6
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Ob antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-MED1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:2
Mediator modulates Gli3-dependent Sonic hedgehog signaling. 2006 to the paper
Santa Cruz Biotechnology MED12 antibody was used in western blot to study the mechanism by which Gli proteins regulate target gene transcription in the nucleus. more
total:2
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Aviva polyclonal anti-MED17 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:4
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
BD Pharmingen monoclonal anti-MED23 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:1
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 to the paper
Santa Cruz Biotechnology Med24 antibody was used in chromatin immunoprecipitation to study the recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 by leptin and its stimulation of breast cancer cells.
total:1
High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency. 2010 to the paper
Molecular Probes anti-Complex II 70kD subunit antibody was used to perform western blot in order to study the role of the mutations in NUBPL and FOXRED1 in human complex I deficiency.
total:2
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam rabbit anti-Med6 polyclonal antibody was used to perform western blot in order to study how the Mediator initiated Gal4 transcription. more
total:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 to the paper
BD Biosciences mouse monoclonal anti-TIF2 antibody was used in western blot (1:500) and immunohistochemistry (1:500) to assess the consequences of reducing expression of the transcription intermediary factor 2 (TIF2) coactivator on prostate cancer cell growth. more
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:28
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-PPAR gamma antibody was used to carry out western blot analysis and Ch-IP assays in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 to the paper
Santa Cruz Biotechnology anti-PGC-1-alpha rabbit polyclonal antibody was used to carry out immunohistochemistry assays in order to investigate the functional role of Myc in mediating hypertrophic cardiomyopathy and heart failure. more
total:14
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Santa Cruz Biotechnology polyclonal RXRs antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways. more
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:12
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 to the paper
Affinity BioReagents anti-SRC1 antibody was used in immunoprecipitation in order to investigate the cooperation between thyroid hormone receptor beta2 and p160 coactivator PAS-B through multiple contact surfaces. more
total:9
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-SRC-3 antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more