TNF signaling
gene
reagent
sample publication
sample review
ADAM17
ADAM metallopeptidase domain 17
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
caspase-8
caspase 8
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
FADD
Fas associated via death domain
total:19
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 to the paper
Cell Signaling Technology anti-FADD antibody was used to perform western blot in order to assess the effect of Rk1 on cell viability and telomerase activity. more
RIP
receptor interacting serine/threonine kinase 1
total:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-RIP antibody was used in western blot to study the effect of repression of NF-kB and activation of AP-1 on apoptosis in prostate cancer cells. more
TNF-alpha
tumor necrosis factor
total:68
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 to the paper
eBioscience anti-TNFa-PE or -APC antibody was used to perform flow cytometry in order to study the diffrent trafficking mechanisms of endosomal TLRs mediated by UNC93B1. more
TNFR1
TNF receptor superfamily member 1A
total:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 to the paper
Santa Cruz anti-TNFR1 antibody was used to perform western blot in order to study the mechanism that TRAF2 inhibits stress-induced cell death. more
TRAF2
TNF receptor associated factor 2
total:26
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF2 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more